This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy. Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these. Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding. This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery
The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.
This book offers remarkable coverage of liver cancer from etiology to prevention and treatment. It provides an updated and new vision of this major cancer that continues to affect hundreds of thousands of people and remains one of the leading causes of cancer deaths around the world. To ensure the high quality of this book, important insights are included and rigorously discussed in a simple and authentic way. The book includes detailed and updated descriptions of the main causes of liver cancer and also the prevention and treatment of this disease. This book is a relevant source of knowledge, very useful for researchers, medical doctors, medical residents, students, healthcare providers, public health decision makers, and all individuals interested in the prevention of this disease.
Dx/Rx: Liver Cancer is a quick and practical reference guide containing all aspects of the diagnosis and therapy of hepatocellular carcinoma (HCC), prognostic and staging systems, clinical management, molecular biology, current controversies, and future insights. Organized into a condensed, bulleted format, this concise reference offers precise and up-to-date information on the epidemiology, classification, diagnosis, treatment, and risk factors for cancers of the liver. Presented in a handy, easy-to-read format, Dx/Rx: Liver Cancer is a must-have resource for oncologists, internists, primary care physicians, and other health care professionals on the ward or in the clinic.
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Navigate the complexities of liver cancer with "Liver Cancer: A Comprehensive Resource for Patients and Families." This essential guide is a beacon of knowledge, empathy, and support, offering in-depth insights into every aspect of liver cancer, from understanding the disease to managing life during and after treatment. Understanding Liver CancerThe book begins with a foundational overview of liver cancer, detailing its types and prevalence, and discussing the risk factors involved. This sets the stage for a deeper exploration and understanding of the disease. The Liver's Anatomy and FunctionLearn about the liver's critical role in the body, how it functions, and the impact liver cancer has on these vital processes. This section lays the groundwork for understanding the challenges and treatment approaches for liver cancer. Causes and Early DetectionDelve into the causes and risk factors of liver cancer, including genetic and environmental aspects. Understand the importance of early detection and the various diagnostic tests and imaging techniques used in identifying liver cancer. Navigating Treatment OptionsExplore comprehensive treatment approaches, from surgical options to chemotherapy, radiation, and innovative therapies like targeted therapy and immunotherapy. This section provides crucial information for making informed decisions about care and treatment. Living with Liver CancerAddress the day-to-day challenges of living with liver cancer, including symptom management, dietary changes, and coping with emotional and psychological impacts. This section offers practical advice for patients and caregivers alike. Palliative Care and Quality of LifeUnderstand the principles and goals of palliative care, focusing on improving the quality of life and managing symptoms effectively. It also discusses navigating end-of-life decisions with dignity and compassion. Emotional and Psychological SupportFind guidance on coping with the emotional impact of liver cancer. Learn about the importance of support systems, counseling, and the role of community and support groups in the healing journey. Special ConsiderationsGain insights into how liver cancer affects different populations, including considerations for pediatric and elderly patients, and the unique aspects of liver cancer in men and women. Advances in Research and TreatmentStay informed about the latest in liver cancer research and emerging treatments. This section highlights the importance of clinical trials and the future possibilities in liver cancer treatment. Nutrition, Physical Activity, and CaregivingDiscover the importance of nutrition and physical activity in managing liver cancer. Additionally, this book provides invaluable resources and strategies for caregivers, emphasizing the importance of their role and self-care. Advocacy and AwarenessUnderstand the importance of promoting liver health, advocating for liver cancer research, and building a supportive community to aid in awareness and support. "Liver Cancer: A Comprehensive Resource for Patients and Families" is more than a book; it's a guide to navigating the challenging journey of liver cancer. It's an indispensable resource, offering comfort, clarity, and hope to those affected by this disease.
Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications. Provides the latest information on liver cancer research Offers outstanding and original reviews on a range of topics focused on liver cancer Serves as an indispensable reference on liver cancer for researchers and students alike
This essential book is a compendium of papers written by an international team of world-renowned experts, who cover topics in their respective areas of expertise. Presenting the most up-to-date knowledge of hepatocellular carcinoma, it covers all topics ? including those more controversial ones ? in this rapidly advancing field, from epidemiology to prevention, from molecular biology to gross pathology, from screening to atypical presentation, from diagnosis to treatment, and from assessment to choice of appropriate treatment. This volume is therefore an important contribution to the field of hepatocellular carcinoma.
