BradyGames'Jak II Official Strategy Guidefeatures detailed maps, with call-outs for items. Strategies for completing every mission, plus every Precursor Orb is unearthed. Tactics to master every one of Jak's moves and attacks. Haven City and its surroundings are explored completely, plus all game secrets revealed! This product is available for sale in North America only.
Naughty Dog are responsible for developing some of the most iconic games of this generation including Crash Bandicoot, Jak and Daxter and Uncharted. Now they invite you on a 30-year retrospective tour with this beautifully designed volume. Charting their 30-year history from being the precocious pup of the gaming world, to their current status as one of the industry's pedigree breeds, The Art of Naughty Dog is a comprehensive guide to one of the most influential game developers in the world. This volume collects decades of production art, essays and inside stories.
The Guide of the Year for the Game of the Year As the action heats up in Haven City, let us lead you safely through the mayhem. This complete Official Guide comprehensively details all missions, secrets, characters (including Daxter's many leading ladies), enemies, items, vehicles, and mini-games. Such invaluable information is spiced up by the frank and uncensored views of the World's Most Popular Ottsel, as well as the odd sarcastic remarks form Pecker, the World's Most Machiavellian Monkaw. Dare you miss out? -Flowcharts for every mission for optimal game orientation -All missions detailed in a step-by-step walkthrough, complete with helpful screenshots -Comprehensive maps of every mission, featuring locations of enemies and items -Extended back cover folds out for easy access to map key. Also works as a handy scoop for Monkaw droppings A dedicated secrets chapter reveals: -Where to find every single Precursor Orb -What to do with those precious Skull Gems -Complete details of all bonus missions -All you need to know about the hidden Secrets menu This definitive Jak 3TM companion features amazing exclusive artwork, high resolution screenshots, interviews with developer Naughty Dog in a dedicated 'Behind the Scenes' section, not to mention all you need to know about Jak and Daxter's adventures to date. Loaded with special information from the game's creators, this guide features all you'll ever need to know about Jak 3 . . . and more
Forget the 10,000 hour rule— what if it’s possible to learn the basics of any new skill in 20 hours or less? Take a moment to consider how many things you want to learn to do. What’s on your list? What’s holding you back from getting started? Are you worried about the time and effort it takes to acquire new skills—time you don’t have and effort you can’t spare? Research suggests it takes 10,000 hours to develop a new skill. In this nonstop world when will you ever find that much time and energy? To make matters worse, the early hours of practicing something new are always the most frustrating. That’s why it’s difficult to learn how to speak a new language, play an instrument, hit a golf ball, or shoot great photos. It’s so much easier to watch TV or surf the web . . . In The First 20 Hours, Josh Kaufman offers a systematic approach to rapid skill acquisition— how to learn any new skill as quickly as possible. His method shows you how to deconstruct complex skills, maximize productive practice, and remove common learning barriers. By completing just 20 hours of focused, deliberate practice you’ll go from knowing absolutely nothing to performing noticeably well. Kaufman personally field-tested the methods in this book. You’ll have a front row seat as he develops a personal yoga practice, writes his own web-based computer programs, teaches himself to touch type on a nonstandard keyboard, explores the oldest and most complex board game in history, picks up the ukulele, and learns how to windsurf. Here are a few of the simple techniques he teaches: Define your target performance level: Figure out what your desired level of skill looks like, what you’re trying to achieve, and what you’ll be able to do when you’re done. The more specific, the better. Deconstruct the skill: Most of the things we think of as skills are actually bundles of smaller subskills. If you break down the subcomponents, it’s easier to figure out which ones are most important and practice those first. Eliminate barriers to practice: Removing common distractions and unnecessary effort makes it much easier to sit down and focus on deliberate practice. Create fast feedback loops: Getting accurate, real-time information about how well you’re performing during practice makes it much easier to improve. Whether you want to paint a portrait, launch a start-up, fly an airplane, or juggle flaming chainsaws, The First 20 Hours will help you pick up the basics of any skill in record time . . . and have more fun along the way.
JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies and cancer. This book provides comprehensive insights into the latest basic and clinical developments in the field. The first part reviews recent findings and new technologies pertaining to basics of Jak-Stat function. The second part describes the evolution of Jak-Stat signaling and the role of the pathway in invertebrate organisms. The third part focuses on Jak-Stat signaling in hematopoietic cells under both physiological and pathophysiological conditions. Finally, chapters in the fourth section describe the relationship of Jak-Stat signaling to various states of disease, particularly infection, leukemias and solid cancers. The book is intended for all scientists in molecular biology, biochemistry and cell biology dealing with biomedical issues.
BradyGames' Ape Escape 2 Official Strategy Guidefeatures a step-by-step walkthrough to guide players through every environment. Coverage of each delinquent monkey, and all mini-games. Expert boss tactics, plus complete item and vehicle lists. Game secrets revealed, and more!
This book reviews current understanding of the biological roles of the signal transducer and activator of transcription (STAT) proteins and their dysregulation in diseases. STAT proteins were named after their role as signal transducers and activators of transcription. STAT proteins are highly conserved among species, thus reflecting the importance