Adverse Effects of Pertussis and Rubella Vaccines
Adverse Effects of Pertussis and Rubella Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1991-02-01

Total Pages: 382

ISBN-13: 0309103681

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Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.

Maternal Immunization
Maternal Immunization

Author: Elke Leuridan

Publisher: Academic Press

Published: 2019-11-26

Total Pages: 396

ISBN-13: 0128145838

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Immunization during pregnancy with currently recommended vaccines prevents infection in the mother, the unborn fetus, and the young infant, and there is an increasing focus from different stakeholders to use this approach for other infections of importance to protect these vulnerable groups. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of vaccines in pregnancy, safety, immunogenicity (immunology), timing to vaccinate, repeat doses, protective effects in the mother, fetus, and infant, and public acceptance and implementation, of existing and of future vaccines. - Provides an overview of a quickly evolving topic. This will benefit the reader who wishes to rapidly become informed and up-to-date with new developments in this field - Suitable to a broad audience: scientific researchers, obstetricians, gynecologists, neonatologists, vaccinators, pediatricians, students, and industry. Maternal vaccination impacts a wide range of specialists - Allows health care professionals/researchers to gain insight into other aspects of vaccination in pregnancy outside of their specialism - Is coauthored by specialists from multiple disciplines, providing a diverse view of the subject, increasing its interest and appeal - Creates awareness of the current developments in this area of medicine and of the potential of maternal vaccination to improve the health of mothers and infants worldwide

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published: 1993

Total Pages: 704

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.

Pertussis
Pertussis

Author: Pejman Rohani

Publisher: Oxford University Press

Published: 2018-12-06

Total Pages: 288

ISBN-13: 0192539868

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Pertussis, or whooping cough, is a respiratory disease caused primarily by infection with the bacterium Bordetella pertussis. It remains among the leading causes of death amongst vaccine-preventable diseases worldwide and recent years have seen its alarming re-emergence in many regions (including the U.S. and much of Europe), despite sustained high levels of vaccine coverage. The causes of the resurgence remain contentious, in part due to inherent complexities of the pathogen's biology, in part due to pronounced variation in the treatment and prevention strategies between different countries and regions, and in part due to long-standing disagreement amongst scientific researchers studying pertussis. This edited volume brings together expert knowledge from disparate fields with the overall aim of synthesizing the current understanding of this critically important, global pathogen.

Adverse Effects of Vaccines
Adverse Effects of Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-04-26

Total Pages: 894

ISBN-13: 0309214351

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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

A Shot in the Dark
A Shot in the Dark

Author: Harris Livermore Coulter

Publisher: Penguin

Published: 1991-01-01

Total Pages: 268

ISBN-13: 9780895294630

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Every week, tens of thousands of children across America are injected with the DPT (diphtheria-pertussis-tetanus) vaccine. The law requires it, and most children will get four DPT shots before they are two years old. But what if one of the components of the vaccine was not safe? What if it caused not only pain, swelling, screaming, and high fever, but also shock, convulsions, brain damage, and even death? And, to make matters worse, what if there were a safer alternative but parents didn't know about it? Wouldn't the government require the drug manufacturers to produce the safer vaccine to protect the lives of the children who might otherwise suffer the shot's crippling side effects? The answer is, unfortunately, no. A Shot in the Dark is a chilling account of just how dangerous the whole-cell pertussis vaccine (the "P" part of the DPT shot) has proven to be. It provides accurate research into the history of the vaccine's development and usage. It exposes the roles played by the FDA and drug companies. It tells the tragic stories of the young victims of the vaccine. This book is also a guide for rightfully concerned parents who are looking for answers to important questions. What are the warning signs to look for to tell if your child is likely to be sensitive to the vaccine? What should parents ask their doctors about the vaccine and their child's medical profile? What is being done, here and in other countries, to combat this frightening situation? What can parents do now to help? A Shot in the Dark is a responsible, eye-opening look at a potential problem that every parent of every young child living in this country must face. Armed with the facts in this important book, parents will be able to make informed decisions about their real medical options. Book jacket.