Adverse Effects of Pertussis and Rubella Vaccines
Adverse Effects of Pertussis and Rubella Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1991-02-01

Total Pages: 382

ISBN-13: 0309103681

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Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published: 1993

Total Pages: 704

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.

Maternal Immunization
Maternal Immunization

Author: Elke Leuridan

Publisher: Academic Press

Published: 2019-11-26

Total Pages: 396

ISBN-13: 0128145838

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Immunization during pregnancy with currently recommended vaccines prevents infection in the mother, the unborn fetus, and the young infant, and there is an increasing focus from different stakeholders to use this approach for other infections of importance to protect these vulnerable groups. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of vaccines in pregnancy, safety, immunogenicity (immunology), timing to vaccinate, repeat doses, protective effects in the mother, fetus, and infant, and public acceptance and implementation, of existing and of future vaccines. - Provides an overview of a quickly evolving topic. This will benefit the reader who wishes to rapidly become informed and up-to-date with new developments in this field - Suitable to a broad audience: scientific researchers, obstetricians, gynecologists, neonatologists, vaccinators, pediatricians, students, and industry. Maternal vaccination impacts a wide range of specialists - Allows health care professionals/researchers to gain insight into other aspects of vaccination in pregnancy outside of their specialism - Is coauthored by specialists from multiple disciplines, providing a diverse view of the subject, increasing its interest and appeal - Creates awareness of the current developments in this area of medicine and of the potential of maternal vaccination to improve the health of mothers and infants worldwide

Recent Developments in Prophylactic Immunization
Recent Developments in Prophylactic Immunization

Author: Francis J. Zucker

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 351

ISBN-13: 9400910673

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It has been said that "never in the history of human progress has a better and cheaper method of preventing illness been developed than immunization". This is well illustrated by the WHO Expanded Programme on Immunization (EPI) which in developing countries is now preventing nearly a million deaths annually from measles, pertussis and neonatal tetanus, and for which there is a commitment by the WHO and UNICEF to protect all children by immunization by the end of the decade. This enormous undertaking will be facilitated by the rapid advances in molecular biology and recombinant DNA technology, in the understanding of immunological mechanisms and by the production and application of monoclonal antibodies so that the structure and location of important antigenic determinants or epitopes can be determined. Chemical synthesis of oligopeptides has been simplified, and computer programmes and X-ray crystallography provide the tools for the determination of three-dimensional structure of proteins, so that the structure and location of important antigenic determinants or epitopes can be predicted. These techniques have opened the way to the improvement of existing vaccines and to the development and production of new vaccines against infections for which vaccines are not available. New vaccines under development include vaccines against hepatitis B, hepatitis A, malaria, vaccines for typhoid, cholera, rota virus infection and other diarrhoeal diseases, leprosy, rabies, the acquired immune deficiency syndrome (AIDS), rubella, EB virus, schistosomiasis and other infections. These recent developments are discussed in the volume by internationally recognized experts assembled from several countries.

Bacterial Infections of Humans
Bacterial Infections of Humans

Author: Alfred S. Evans

Publisher: Springer

Published: 2013-04-18

Total Pages: 727

ISBN-13: 1475711409

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This is a companion volume to Viral Infections of Humans: Epidemiology and Control. The apparent success of that book in bridging the gap between texts on basic microbiology and those on clinical infectious diseases led to editing this one on bacterial infections, the chapters of which are organized in exactly the same format of 12 units: introduction, historical background, methodology, biological characteristics of the organism, descriptive epidemiology, mechanisms and routes of transmission, pathogenesis and im munity, patterns of host response, control and prevention, unresolved problems, references, and suggested reading. The purpose of this book is to provide a description and understanding of the pathogenesis of infection and disease both within the community and within the individual. This is done in the belief that a variety of factors in both the external and the internal environment, and in the nature of the infectious agent, influence exposure, the development of infection, and the pattern of the host response. An understanding of the epidemiology and pathogenesis of these processes forms the basis for approaches to control and prevention. The first two chapters of this book deal with general epidemiological concepts and with surveillance.

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques

Author: JUCKER

Publisher: Birkhäuser

Published: 2013-03-07

Total Pages: 540

ISBN-13: 3034891547

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In the first years of the existence of this series of monographs, during the so-called "Golden Age" of drug research, the majority of the pa pers published were mainly concerned with the traditional domains of drug research, namely chemistry, pharmacology, toxicology and pre clinical investigations. The series' aim was to give coverage to impor tant areas of research, to introduce new active substances with thera peutic potential and to call attention to unsolved problems. This objective has not changed. The table of contents of the present volume makes evident, however, that the search for new medicines has become increasingly complex, and additional, new disciplines have entered the research arena. The series now includes reviews on bio chemical, biological, immunological, physiological and medicinal aspects of drug research. Researchers actively engaged in the various scientific fields forming the entity of drug research can benefit from the wealth of knowledge and experience of the respective authors, and will be assisted in their endeavour to discover new pharmaceutical agents. Those simply wanting to keep abreast of new developments in the complex, multi-discipline science can turn to the "Progress in Drug Research" volumes as an almost encyclopaedic source of information without having to consult the innumerable original publications. Volume 32 contains 12 reviews, a subject index, an index for the close to 400 articles published in the series so far, and an author and titles index for all 32 volumes.