Immune Response and the Eye
Immune Response and the Eye

Author: Jerry Y. Niederkorn

Publisher: Karger Medical and Scientific Publishers

Published: 2007-01-01

Total Pages: 357

ISBN-13: 3805581874

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In memory of J. Wayne Streilein, the pioneer in ocular immunology The second edition of Immune Response and the Eye' highlights recent insights into the dangerous compromise' between the immune system and the eye, which protects the eye against pathogens while limiting inflammation and immune-mediated injury to ocular tissues with little or no regenerative potential. It discusses the broad spectrum of physiological, immunological, anatomical, and biochemical adaptations that conspire to closely regulate the tone and tenor of immune responses in the eye. This volume further describes immune-mediated diseases that occur when the compromise between the immune system and the eye is breached. This breakdown in immune privilege threatens the vision of millions each year. Finally, recent advances in ocular immunology are presented, which offer potential therapeutic applications in corneal and retinal transplantation and in the management of blinding autoimmune diseases of the eye. Eye researchers, ophthalmologists and immunologists will appreciate the state-of-the-art and authoritative information presented in Immune Response and the Eye'

Immunology, Inflammation and Diseases of the Eye
Immunology, Inflammation and Diseases of the Eye

Author: Darlene A. Dartt

Publisher: Academic Press

Published: 2011-02-26

Total Pages: 451

ISBN-13: 012381975X

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This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more. - The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology - Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers - The best researchers in the field provide their conclusions in the context of the latest experimental results

Immune Response and the Eye
Immune Response and the Eye

Author: J. Wayne Streilein

Publisher: Karger Medical and Scientific Publishers

Published: 1999-01-01

Total Pages: 239

ISBN-13: 3805568932

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In this book, the physiologic bases of ocular immune privilege and the distinctive systemic immune responses elicited by eye derived antigens are described. Several chapters discuss the pathogeneses of these disorders which arise from infections, autoimmunity, and neoplasms. Finally, chapters devoted to corneal and retinal transplantation describe attempts to exploit ocular immune privilege to promote graft survival and thereby cure blindness. Ophthalmologists, both clinicians and physician scientists, general and tumor immunologists, transplantation biologists and anyone seeking to understand the immunopathogenic diseases that threaten vision will appreciate the information presented in this book.

Whitcup and Nussenblatt's Uveitis
Whitcup and Nussenblatt's Uveitis

Author: Scott M. Whitcup

Publisher: Elsevier Health Sciences

Published: 2021-03-31

Total Pages: 432

ISBN-13: 0323789595

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Comprehensive and readable, Whitcup and Nussenblatt's Uveitis, 5th Edition, covers every aspect of this complex subspecialty in a single convenient volume. This clinically relevant guide covers the medical, pharmacological, and surgical treatment of uveitis in a visually rich, full-color format, offering a complete overview for today's clinicians. New and updated case studies, key points boxes, and more than 400 images and graphics highlight major clinical points and provide insight into real situations that you can apply in practice. - Features multiple chapters on diagnostic approach to help you meet the challenge of making accurate diagnoses. - Reflects advancements and new developments on all aspects of uveitis including new medical and surgical treatments. - Covers key topics such as the use of PCR in diagnostic testing, cataract surgery in patients with uveitis, the use of OCT in diagnosis and treatment, new infectious causes of uveitis (including Zika and Ebola), and novel treatments for inflammatory eye disease. - Includes new clinical photographs, illustrations, and OCT images throughout. - Reviews new randomized clinical trials of new uveitis therapy, as well as the approach to patients with HIV and HIV-associated ocular diseases including CMV retinitis and immune recovery uveitis. - Provides expanded information on masquerade syndromes with important tips on diagnosis and management of intraocular lymphoma.

Janeway's Immunobiology
Janeway's Immunobiology

Author: Kenneth Murphy

Publisher: Garland Science

Published: 2010-06-22

Total Pages:

ISBN-13: 9780815344575

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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Mucosal Vaccines
Mucosal Vaccines

Author: Hiroshi Kiyono

Publisher: Elsevier

Published: 1996-10-23

Total Pages: 501

ISBN-13: 0080537057

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This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. - Provides the latest views on mucosal vaccines - Applies basic principles to the development of new vaccines - Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases - Unique and user-friendly organization

Ocular Therapeutics
Ocular Therapeutics

Author: Thomas Yorio

Publisher: Academic Press

Published: 2011-04-28

Total Pages: 537

ISBN-13: 0080556779

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Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.* Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.* Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases.* Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway.* New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States

Complications in Uveitis
Complications in Uveitis

Author: Francesco Pichi

Publisher: Springer Nature

Published: 2020-01-27

Total Pages: 276

ISBN-13: 3030283925

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This book will focus for the first time on how to avoid complications of uveitis, or how to deal with them either surgically or medically. Its uniqueness lies in the fact that all other books available on the subject of uveitis concentrate on pathogenesis, natural course, diagnosis and treatment of the uveitic entity itself, barely touching complications arising from inflammation. This book will be divided in chapters, each of them concentrating on a particular portion of the eye, from front to back, and how it can get affected by complications from inflammation. Inflammatory diseases causing these complications will be just superficially touched, the main focus will be the pathogenesis of the actual complication, prevention and treatment. Every chapter will be introduced by a section by a uveitis specialist on how inflammation can cause that particular complication, and how we can avoid it. Then a specialist in the sector (cornea surgeon, glaucoma surgeon, etc) will describe management of the complication. This multi-disciplinary approach to complications of uveitis will provide to the readers the tools to prevent them, or to correctly manage the. It will be a book mainly directed to uveitis specialist but that could also interest other specialists.

Common Eye Infections
Common Eye Infections

Author: Imtiaz Chaudhry

Publisher: BoD – Books on Demand

Published: 2013-05-08

Total Pages: 268

ISBN-13: 953510926X

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Since ocular infections are one of the most frequent occurrences in ophthalmology, the treatment for these infections must be fast, precise and effective. In order to address this goal, it is important to identify and characterize the culprit microorganisms involved in the pathogenesis of ocular infections. Clinical diagnosis of ocular infections can be confirmed by several techniques based on microbiological test of ocular samples. Some of these techniques include classic microbiological testing in which it is necessary to isolate microorganisms to characterize them by biochemical analysis which require significant resources and timing.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field
Military Strategies for Sustainment of Nutrition and Immune Function in the Field

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1999-05-13

Total Pages: 722

ISBN-13: 0309173183

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Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.