IFM’99
IFM’99

Author: Keijiro Araki

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 480

ISBN-13: 1447108515

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Formal methods have been established as the rigorous engineering methodology for the system development. Applying formal methods to a large and complex system development often requires the modelling of different aspects of such a system. For instance, complex systems (such as integrated avionics systems, engine control software) can involve functional and timing requirements that must be eventually implemented as executing code on a communicating distributed topology. This book contains the papers presented at the First International Workshop on Integrated Formal Methods, held at the University of York in June 1999. The conference provided a forum for the discussion of theoretical aspects of combing behavioural and state-based formalisms and practical solutions to the industrial problems of this approach.

Myeloma Therapy
Myeloma Therapy

Author: Sagar Lonial

Publisher: Springer Science & Business Media

Published: 2009-01-01

Total Pages: 674

ISBN-13: 1597455644

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Therapeutic options for patients with myeloma have dramatically changed over the past 10 years. Beginning with the advances in therapy resulting from the use of high-dose therapy and autologous bone marrow or stem cell tra- plant, we have more than doubled the median survival for patients as a whole, and have now have a wealth of different biology -based treatment approaches for our patients in all disease stages. This book represents state-of-the-art information from many of the leaders in the plasma cell disorders world. Sections focusing on disease pathogenesis and biology, chemotherapy-based approaches, immune -based therapies, currently approved novel agents, developing targets, supportive care, and other plasma cell disorders provides a comprehensive collection and an excellent resource in this time of rapid change in clinical and preclinical disease knowledge. It is important to realize that these changes did not occur in a vacuum. Partnerships between academic institutions, the pharmaceutical industry, patient advocacy groups, the National Cancer Institute, community onco- gists, and ultimately our patients worked closely together to realize these advances, and to effect the radical changes in therapy we have witnessed over the past few years. This book would not have been possible without contri- tions from each of the gifted scientists and clinicians who worked tirelessly to prepare their individual chapters all the while maintaining commitment to the scientific and clinical mission of advancing care.

Multiple Myeloma
Multiple Myeloma

Author: Thomas Moehler

Publisher: Springer Science & Business Media

Published: 2011-04-21

Total Pages: 349

ISBN-13: 3540857729

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Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Multiple Myeloma
Multiple Myeloma

Author: Roman Hajek

Publisher: BoD – Books on Demand

Published: 2013-04-10

Total Pages: 338

ISBN-13: 9535110837

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This book does not provide a comprehensive overview of Multiple Myeloma but a collection of chapters with in-depth information of distinct hot topics in the diagnostic, research and therapeutic fields. The dynamics of testing new drugs for multiple myeloma treatment in clinical trials is breathtaking. Scientific discoveries have uncovered complicated pathogenesis of multiple myeloma; complicated reactions to treatment lead to the creation of super cocktails. Curability of multiple myeloma is a question that is being discussed by the entire professional myeloma world. Improvement of prognosis is a fact which is most important from a patient's perspective. We believe that this book could be of interest to medical professionals specializing in hematooncology, researchers, as well as many others.

Multiple Myeloma
Multiple Myeloma

Author: Morie A. Gertz

Publisher: Springer Science & Business Media

Published: 2013-10-01

Total Pages: 311

ISBN-13: 1461485207

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This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

Wintrobe's Clinical Hematology
Wintrobe's Clinical Hematology

Author: John P. Greer

Publisher: Lippincott Williams & Wilkins

Published: 2018-11-19

Total Pages: 7970

ISBN-13: 1496367138

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Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. This extensive title, which combines scientific principles with up-to-date clinical procedures, has been thoroughly updated for the fourteenth edition. You’ll find in-depth material on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them.

Myeloma
Myeloma

Author: Stephen A. Schey

Publisher: Cambridge University Press

Published: 2013-12-05

Total Pages: 307

ISBN-13: 1107010578

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Myeloma is the second-most common hematologic cancer, accounting for approximately 1 percent of all cancers and 2 percent of all deaths from cancer. In recent years there have been major and significant advances in the diagnosis, imaging, molecular pathogenesis, and therapy of myeloma. This book describes these advances in a single, practical volume, placing them in the context of daily clinical practice. Different myeloma subtypes are discussed in individual chapters, integrating etiology, pathogenesis, molecular pathology, histology, and therapy in a single place for each condition. The book begins by discussing epidemiology, imaging techniques, pathogenesis, and other general considerations. Conditions covered in detail include multiple myeloma, POEMS syndrome, Castleman's syndrome, Waldenstrom's macroglobulinemia, amyloidosis and MGUS. Featuring color illustrations, and written and edited by leading authorities in the field, Myeloma provides readers with the information they need to diagnose and manage these complex disorders.

Postgraduate Haematology
Postgraduate Haematology

Author: Anthony R. Green

Publisher: John Wiley & Sons

Published: 2010-11-01

Total Pages: 1076

ISBN-13: 1405191805

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The textbook of choice for trainees in haematology Over five editions Postgraduate Haematology has built a reputation as an extremely practical, user-friendly, reliable source of information for examination preparation and clinical practice. Completely revised to reflect the latest research in the field, this edition continues to provide trainees with up-to-date knowledge on the pathogenesis, clinical and laboratory features, and management of blood disorders. It covers the significant advances which have occurred in the application of cytogenetics and molecular genetics in the diagnosis, classification and understanding of haematological disorders. Coupled with the expertise of 34 new contributors from across Europe, the editors have been joined by Professor Anthony Green, from the University of Cambridge, and they have reorganised the book into 52 accessible chapters. Postgraduate Haematology is richly illustrated throughout with over 200 colour illustrations including line drawings, photomicrographs of blood cells and tissues, and algorithms to help aid treatment decision making. It is an indispensable resource for trainees and an essential read for all specialists who are interested in updating their knowledge.

Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation

Author: Robert J. Soiffer

Publisher: Springer Science & Business Media

Published: 2008-11-14

Total Pages: 734

ISBN-13: 1597454389

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Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.

Manual of Hematopoietic Cell Transplantation and Cellular Therapies - E-Book
Manual of Hematopoietic Cell Transplantation and Cellular Therapies - E-Book

Author: Qaiser Bashir

Publisher: Elsevier Health Sciences

Published: 2022-12-23

Total Pages: 608

ISBN-13: 0323798349

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Led by authors from MD Anderson's Stem Cell Transplantation and Cellular Therapy Department, the world's largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies. - Addresses hematologic conditions including leukemia, lymphoma, and myeloma. - Offers guidance on hematopoietic cell transplantation for solid tumors. - Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications. - Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT. - Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference. - Offers team-based, clinically-focused coverage from world-renowned leaders in the field.