'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine
'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

Author: Nosheen Masood

Publisher: Springer Nature

Published: 2020-03-20

Total Pages: 498

ISBN-13: 9811510679

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This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.

Understanding Neighbourhood Dynamics
Understanding Neighbourhood Dynamics

Author: Maarten van Ham

Publisher: Springer Science & Business Media

Published: 2012-09-27

Total Pages: 291

ISBN-13: 9400748531

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This rare interdisciplinary combination of research into neighbourhood dynamics and effects attempts to unravel the complex relationship between disadvantaged neighbourhoods and the life outcomes of the residents who live therein. It seeks to overcome the notorious difficulties of establishing an empirical causal relationship between living in a disadvantaged area and the poorer health and well-being often found in such places. There remains a widespread belief in neighbourhood effects: that living in a poorer area can adversely affect residents’ life chances. These chapters caution that neighbourhood effects cannot be fully understood without a profound understanding of the changes to, and selective mobility into and out of, these areas. Featuring fresh research findings from a number of countries and data sources, including from the UK, Australia, Sweden and the USA, this book offers fresh perspectives on neighbourhood choice and dynamics, as well as new material for social scientists, geographers and policy makers alike. It enriches neighbourhood effects research with insights from the closely related, but currently largely separate, literature on neighbourhood dynamics.

The Art of Structuring
The Art of Structuring

Author: Katrin Bergener

Publisher: Springer

Published: 2019-01-25

Total Pages: 535

ISBN-13: 3030062341

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Structuring, or, as it is referred to in the title of this book, the art of structuring, is one of the core elements in the discipline of Information Systems. While the world is becoming increasingly complex, and a growing number of disciplines are evolving to help make it a better place, structure is what is needed in order to understand and combine the various perspectives and approaches involved. Structure is the essential component that allows us to bridge the gaps between these different worlds, and offers a medium for communication and exchange. The contributions in this book build these bridges, which are vital in order to communicate between different worlds of thought and methodology – be it between Information Systems (IS) research and practice, or between IS research and other research disciplines. They describe how structuring can be and should be done so as to foster communication and collaboration. The topics covered reflect various layers of structure that can serve as bridges: models, processes, data, organizations, and technologies. In turn, these aspects are complemented by visionary outlooks on how structure influences the field.

Statistics of Financial Markets
Statistics of Financial Markets

Author: Szymon Borak

Publisher: Springer Science & Business Media

Published: 2013-01-11

Total Pages: 266

ISBN-13: 3642339298

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Practice makes perfect. Therefore the best method of mastering models is working with them. This book contains a large collection of exercises and solutions which will help explain the statistics of financial markets. These practical examples are carefully presented and provide computational solutions to specific problems, all of which are calculated using R and Matlab. This study additionally looks at the concept of corresponding Quantlets, the name given to these program codes and which follow the name scheme SFSxyz123. The book is divided into three main parts, in which option pricing, time series analysis and advanced quantitative statistical techniques in finance is thoroughly discussed. The authors have overall successfully created the ideal balance between theoretical presentation and practical challenges.

The Semantic Web – ISWC 2019
The Semantic Web – ISWC 2019

Author: Chiara Ghidini

Publisher: Springer Nature

Published: 2019-10-17

Total Pages: 794

ISBN-13: 303030793X

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The two-volume set of LNCS 11778 and 11779 constitutes the refereed proceedings of the 18th International Semantic Web Conference, ISWC 2019, held in Auckland, New Zealand, in October 2019. The ISWC conference is the premier international forum for the Semantic Web / Linked Data Community. The total of 74 full papers included in this volume was selected from 283 submissions. The conference is organized in three tracks: for the Research Track 42 full papers were selected from 194 submissions; the Resource Track contains 21 full papers, selected from 64 submissions; and the In-Use Track features 11 full papers which were selected from 25 submissions to this track.

Advanced Engineering Optimization Through Intelligent Techniques
Advanced Engineering Optimization Through Intelligent Techniques

Author: R. Venkata Rao

Publisher: Springer

Published: 2019-07-09

Total Pages: 836

ISBN-13: 9811381968

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This book comprises select peer-reviewed papers presented at the International Conference on Advanced Engineering Optimization Through Intelligent Techniques (AEOTIT) 2018. The book combines contributions from academics and industry professionals, and covers advanced optimization techniques across all major engineering disciplines like mechanical, manufacturing, civil, automobile, electrical, chemical, computer and electronics engineering. Different optimization techniques and algorithms such as genetic algorithm (GA), differential evolution (DE), simulated annealing (SA), particle swarm optimization (PSO), artificial bee colony (ABC) algorithm, artificial immune algorithm (AIA), teaching-learning-based optimization (TLBO) algorithm and many other latest meta-heuristic techniques and their applications are discussed. This book will serve as a valuable reference for students, researchers and practitioners and help them in solving a wide range of optimization problems.