History of the Pancreas: Mysteries of a Hidden Organ
History of the Pancreas: Mysteries of a Hidden Organ

Author: John M. Howard

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 763

ISBN-13: 1461505550

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Never before has a comprehensive history of the pancreas like History of the Pancreas been published. It not only is a historical review of the science of medicine, it is liberally interspersed with anecdotal vignettes of the researchers who have worked on this organ. Much of it, such as the discovery of the duct of Wirsüng, of the islets of Langerhans, of insulin, gastrin and their tumors, reads like the adverture, which it is. This book, divided into 14 chapters, is written in a narrative style and is easily readable, as glimpses of the investigators, those who failed as well as those who succeeded, adds both perspective and human interest. Each chapter is completely referenced, totaling over 1500 references. As a reference book for students, teachers, investigators, writers, its detailed hjistorical documentation is unique. From the pre-Christian era of Asia Minor, to Greece, Rome, Europe and America, to the explosive progress in Japan, the history is there. History of the Pancreas: Mysteries of a Hidden Organ fills a gap.

History of the Pancreas: Mysteries of a Hidden Organ
History of the Pancreas: Mysteries of a Hidden Organ

Author: John M. Howard

Publisher: Springer

Published: 2002-11-30

Total Pages: 758

ISBN-13: 9780306467424

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Never before has such a history of the pancreas been presented. From antiquity until today, "rediscovery", translation and sequential presentation, in step with cultural changes in society, make this a unique contribution. Only from the perspective of the two octogenarian-authors could such a narrative have been produced. Discoveries resulting either from chance observation or careful scientific inquiry "come alive" as the authors present not only the people who made them but the setting in which they occurred. Key Features: *From the pre-Christian era of Asia Minor, to Greece, Rome, Europe and America, to the explosive progress in Japan, the dreams, near-misses and great discoveries have been traced to their sources. *The great discoveries of the anatomists, Wirsüng, Santorini, Oddi, Vater and their colleagues have been recreated from their original reports. *Physiology is traced through the discovery of the digestive enzymes; the islets, by the Berlin student for whom they were named; the hormones, beginning with the dramatic discoveries of insulin, gastrin and their fascinating tumors. *Diseases of the pancreas, particularly pancreatitis and cancer, but also congenital anomalies and trauma, are described from the era preceding the microscope to the dawn of the 21st Century. *The explosive developments of imaging, diagnosis and pancreatic transplantation are presented, leading to the development of the challenging field of Pancreatology - its science and clinical practice. *Finally the authors, having spent many years distilling the contribution of the giants of the past and present, present a thought provoking Chapter entitled "Lessons from History and their Application to the Future".

Diseases of the Abdomen and Pelvis 2018-2021
Diseases of the Abdomen and Pelvis 2018-2021

Author: Juerg Hodler

Publisher: Springer

Published: 2018-03-20

Total Pages: 262

ISBN-13: 3319750194

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This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

The Exocrine Pancreas
The Exocrine Pancreas

Author: Stephen Pandol

Publisher: Morgan & Claypool Publishers

Published: 2011

Total Pages: 66

ISBN-13: 1615041389

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The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.

The Pancreas
The Pancreas

Author: Hans G. Beger

Publisher: John Wiley & Sons

Published: 2018-04-23

Total Pages: 1218

ISBN-13: 1119188393

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This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high-quality illustrations, line drawings, and radiographs that provide a step-by-step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations. Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non-surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors. The most encyclopedic book on the pancreas—providing outstanding and clear guidance for the practicing clinician Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management Completely updated with brand new chapters Over 500 downloadable illustrations An editor and author team of high international repute who present global best-practice The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.

The Discovery of Insulin
The Discovery of Insulin

Author: Michael Bliss

Publisher: University of Toronto Press

Published: 2017-06-22

Total Pages: 524

ISBN-13: 1487516746

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The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Pancreatitis
Pancreatitis

Author: David B. Adams

Publisher: John Wiley & Sons

Published: 2017-02-02

Total Pages: 336

ISBN-13: 1118924924

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Pancreatitis: medical and surgical management provides gastroenterologists and GI surgeons, both fully qualified and in training, with a focused, evidence-based approach to the most exciting developments in the diagnosis and clinical management of pancreatitis. Focusing mainly on the rapidly changing and innovative medical and surgical strategies to manage the disease, new surgical procedures such as endoscopic biliary intervention and minimally invasive necrosectomy to exciting new medical therapies like Antiprotease, Lexipafant, probiotics and enzyme treatment are all discussed. Full colour throughout, with over 250 colour illustrations and with reference to the latest clinical guidelines from the AGA, ACG and UEGW at all times, it is an essential consultation tool for all those managing patients with this increasingly common condition.

Unveiling Diabetes - Historical Milestones in Diabetology
Unveiling Diabetes - Historical Milestones in Diabetology

Author: V. Jörgens

Publisher: Karger Medical and Scientific Publishers

Published: 2020-08-06

Total Pages: 318

ISBN-13: 3318067342

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A history of diabetology told by renowned contributors, many have themselves already become a part of diabetes history. A must-have for every diabetologist! Diabetologists, diabetes educators, and many interested readers will appreciate this book. What is more, countless celebrations are planned for the 100th anniversary of the discovery of insulin: this book provides numerous illustrations, accounts of personal experiences, and critical remarks on the history of diabetology – in addition to the history of insulin. It spans an arc from antiquity to the work of Claude Bernard, Paul Langerhans, Josef von Mering, Apollinaire Bouchardat, Oskar Minkowski, E.P. Joslin, and F.M. Allen. The history of insulin is presented from the perspective of diabetologists from Scotland, Spain, Germany, and Poland. The history of oral antidiabetics is told by Harald Lebovitz, and the chapter about glitazones by Edwin Gale reads like a spy novel! Pierre Lefèbvre describes the work of the diabetologist Jean Pirart and the history of glucagon. Sir George Alberti has provided a chapter about the therapy of ketoacidosis, to which he himself made groundbreaking contributions. Nephropathy is presented by Hans-Henrik Parving, and Eva Kohner, Ronald Klein and Barbara E.K. Klein have contributed a chapter on retinopathy. Other contemporary topics such diabetes in pregnancy, diabetes technology, psychosocial aspects of diabetes, and the history of the EASD and ADA are also included in this book.

Surgical Treatment of Pancreatic Diseases
Surgical Treatment of Pancreatic Diseases

Author: Walter Siquini

Publisher: Springer Science & Business Media

Published: 2010-05-30

Total Pages: 526

ISBN-13: 8847008565

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Pancreatic diseases are a crucial issue not only because of their epidemiological significance, and their anatomical and metabolic complexity, but also because of the different treatment options available and their implications for surgery. Due to the slow but steady increase in the incidence of pancreatitis and pancreatic cancer, these diseases are today a real challenge for the surgeon. This volume presents the state of the art of surgery in the treatment of inflammatory and neoplastic pancreatic diseases, describing in detail the different approaches and their most relevant technical aspects. Also described are conventional and interventional radiology, operative endoscopy and endoscopic ultrasonography (which has recently acquired a diagnostic role), and adjuvant and neoadjuvant therapy for treatment or palliation: for only a multidisciplinary approach can produce a global vision, a winning strategy for the optimization of results. Along with the texts, all written by experts, the volume includes color images and drawings. It will prove itself a very useful tool in clinical practice.