High Resolution Imaging in Microscopy and Ophthalmology

High Resolution Imaging in Microscopy and Ophthalmology

Author: Josef F. Bille

Publisher: Springer

Published: 2019-08-13

Total Pages: 411

ISBN-13: 3030166384

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This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.


Fluorescence Lifetime Imaging Ophthalmoscopy

Fluorescence Lifetime Imaging Ophthalmoscopy

Author: Martin Zinkernagel

Publisher: Springer

Published: 2019-07-29

Total Pages: 123

ISBN-13: 3030228789

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This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.


Anterior Segment Optical Coherence Tomography

Anterior Segment Optical Coherence Tomography

Author: Roger F. Steinert

Publisher: SLACK Incorporated

Published: 2008

Total Pages: 204

ISBN-13: 9781556428081

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High-speed anterior segment optical coherence tomography (OCT) offers a non-contact method for high resolution cross-sectional and three-dimensional imaging of the cornea and the anterior segment of the eye. As the first text completely devoted to this topic, Anterior Segment Optical Coherence Tomography comprehensively explains both the scientific principles and the clinical applications of this exciting and advancing technology. Anterior Segment Optical Coherence Tomography enhances surgical planning and postoperative care for a variety of anterior segment applications by expertly explaining how abnormalities in the anterior chamber angle, cornea, iris, and lens can be identified and evaluated using the Visante OCT(TM). Inside Anterior Segment Optical Coherence Tomography, Dr. Roger Steinert and Dr. David Huang, along with 22 of the field's leading professionals, provide a wealth of useful clinical and physiological material about this new diagnostic imaging technique. Valuable images are included to assist in the pre- and postoperative assessment of various anterior segment disorders. Additionally, this unique resource contains detailed information on biometric measurements to enhance diagnostic capability. On the leading edge of anterior segment imaging: - Mapping of corneal thickness and keratoconus evaluation - Measurement of LASIK flap and stromal bed thickness - Visualization and measurement of anterior chamber angle and diagnosis of narrow angle glaucoma - Measuring the dimensions of the anterior chamber and assessing the fit of intraocular lens implants - Visualizing and measuring the results of corneal implants and lamellar procedures - Imaging through corneal opacity to see internal eye structures With the increase in popularity of anterior chamber imaging, and anterior segment OCT proving to be the best tool for high resolution biometry, Anterior Segment Optical Coherence Tomography is a must-have for anterior segment, refractive, cornea, and glaucoma surgeons.


Optical Coherence Tomography

Optical Coherence Tomography

Author: Wolfgang Drexler

Publisher: Springer Science & Business Media

Published: 2008-12-10

Total Pages: 1346

ISBN-13: 3540775501

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Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.


High Resolution Imaging in Microscopy and Ophthalmology

High Resolution Imaging in Microscopy and Ophthalmology

Author: Josef F. Bille

Publisher:

Published: 2019

Total Pages: 407

ISBN-13: 9783030166397

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This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology - New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.


Multiphoton Microscopy and Fluorescence Lifetime Imaging

Multiphoton Microscopy and Fluorescence Lifetime Imaging

Author: Karsten König

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2018-01-22

Total Pages: 785

ISBN-13: 311043007X

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This monograph focuses on modern femtosecond laser microscopes for two photon imaging and nanoprocessing, on laser tweezers for cell micromanipulation as well as on fluorescence lifetime imaging (FLIM) in Life Sciences. The book starts with an introduction by Dr. Wolfgang Kaiser, pioneer of nonlinear optics and ends with the chapter on clinical multiphoton tomography, the novel high resolution imaging technique. It includes a foreword by the nonlinear microscopy expert Dr. Colin Sheppard. Contents Part I: Basics Brief history of fluorescence lifetime imaging The long journey to the laser and its use for nonlinear optics Advanced TCSPC-FLIM techniques Ultrafast lasers in biophotonics Part II: Modern nonlinear microscopy of live cells STED microscopy: exploring fluorescence lifetime gradients for super-resolution at reduced illumination intensities Principles and applications of temporal-focusing wide-field two-photon microscopy FLIM-FRET microscopy TCSPC FLIM and PLIM for metabolic imaging and oxygen sensing Laser tweezers are sources of two-photon effects Metabolic shifts in cell proliferation and differentiation Femtosecond laser nanoprocessing Cryomultiphoton imaging Part III: Nonlinear tissue imaging Multiphoton Tomography (MPT) Clinical multimodal CARS imaging In vivo multiphoton microscopy of human skin Two-photon microscopy and fluorescence lifetime imaging of the cornea Multiscale correlative imaging of the brain Revealing interaction of dyes and nanomaterials by multiphoton imaging Multiphoton FLIM in cosmetic clinical research Multiphoton microscopy and fluorescence lifetime imaging for resection guidance in malignant glioma surgery Non-invasive single-photon and multi-photon imaging of stem cells and cancer cells in mouse models Bedside assessment of multiphoton tomography


High Resolution Imaging in Microscopy and Ophthalmology

High Resolution Imaging in Microscopy and Ophthalmology

Author: Josef F Bille

Publisher:

Published: 2020-10-09

Total Pages: 410

ISBN-13: 9781013275227

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This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology - New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.


Image Analysis and Modeling in Ophthalmology

Image Analysis and Modeling in Ophthalmology

Author: Eddie Y. K. Ng

Publisher: CRC Press

Published: 2014-02-11

Total Pages: 402

ISBN-13: 1466559381

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Successful thermal modeling of the human eye helps in the early diagnosis of eye abnormalities such as inflammation, cataracts, diabetic retinopathy, and glaucoma-all leading causes of blindness. This book presents a unified work of eye imaging and modeling techniques that have been proposed and applied to ophthalmologic problems. It delves into various morphological, texture, higher order spectra, and wavelet transformation techniques used to extract important diagnostic features from images, which can then be analyzed by a data scientist for automated diagnosis.


Atlas of Anterior Segment Optical Coherence Tomography

Atlas of Anterior Segment Optical Coherence Tomography

Author: Jorge L. Alió

Publisher: Springer Nature

Published: 2020-10-31

Total Pages: 267

ISBN-13: 3030533743

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Part of the Essentials in Ophthalmology series, this atlas is designed to comprehensively cover optical coherence tomography of the anterior segment of the eye. The aim is to improve knowledge of the fundamentals of OCT technology for anterior segment, clarify the differences with posterior segment OCT and emphasize the immense relevance and usefulness that anterior segment OCT study has for diagnosis, therapeutic orientation, surgical guidance, and improvement in patient management. Atlas of Anterior Segment Optical Coherence Tomography is organized into comprehensive chapters on the following topics: fundamentals, technologies and technological differences among platforms, application of OCT, corneal OCT angiography, as well as case-based chapters. Numerous highly-detailed figures, illustrations and photographs make this an ideal resource for the corneal specialist seeking further instruction on this cutting-edge technology. The case-based chapters include such conditions as bowman dystrophies, trauma, cataract, glaucoma, sclera, refractive surgery, ocular infections, and are structured to facilitate the consultant surgeon by providing practical information applicable to practical cases in their practice.


OCT Atlas

OCT Atlas

Author: Nagahisa Yoshimura

Publisher: Springer

Published: 2014-06-24

Total Pages: 0

ISBN-13: 9783642386244

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OCT provided a great advantage over other diagnostic modalities, as it could noninvasively provide tomographic images of the retina of a living eye. As a result, a number of new findings in retinal diseases were made using the time-domain OCT. OCT has now become an essential medical equipment OCT has now become an essential medical equipment in ophthalmic care and quality textbooks describing the functionality of OCT are very important in the education of young ophthalmologists and eye care personnel. In this book are chosen high quality OCT images of rather common diseases as well as images of several rare diseases.