Vaccines: A Biography

Vaccines: A Biography

Author: Andrew W. Artenstein

Publisher: Springer Science & Business Media

Published: 2009-12-11

Total Pages: 403

ISBN-13: 1441911081

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Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natural, historical context. The book traces the lineage – the “biography” – of individual vaccines, originating with deeply rooted medical problems and evolving to an eventual conclusion. Nonetheless, these are not “biographies” in the traditional sense; they do not trace an individual’s growth and development. Instead, they follow an idea as it is conceived and dev- oped, through the contributions of many. These are epic stories of discovery, of risk-takers, of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, “by standing on the shoulders of giants. ” One grant reviewer described the book’s concept as “triumphalist”; although meant as an indictment, this is only partially inaccurate.


The Politics of Knowledge in Inclusive Development and Innovation

The Politics of Knowledge in Inclusive Development and Innovation

Author: David Ludwig

Publisher: Routledge

Published: 2021-10-15

Total Pages: 296

ISBN-13: 1000478726

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This book develops an integrated perspective on the practices and politics of making knowledge work in inclusive development and innovation. While debates about development and innovation commonly appeal to the authority of academic researchers, many current approaches emphasise the plurality of actors with relevant expertise for addressing livelihood challenges. Adopting an action-oriented and reflexive approach, this volume explores the variety of ways in which knowledge works, paying particular attention to dilemmas and controversies. The six parts of the book address the complex interplay of knowledge and politics, starting with the need for knowledge integration in the first part and decolonial perspectives on the politics of knowledge integration in the second part. The following three parts focus on the practices of inclusive development and innovation through three major themes of learning for transformative change, evidence, and digitisation. The final part of the book addresses the governance of knowledge and innovation in the light of political struggles about inclusivity. Exploring conceptual and practical themes through case studies from the Global North and South, this book will be of great interest to students, scholars, and practitioners researching and working in development studies, epistemology, innovation studies, science and technology studies, and sustainability studies more broadly.


Injury Research

Injury Research

Author: Guohua Li

Publisher: Springer Science & Business Media

Published: 2012-01-06

Total Pages: 672

ISBN-13: 1461415985

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Injury is recognized as a major public health issue worldwide. In most countries, injury is the leading cause of death and disability for children and young adults age 1 to 39 years. Each year in the United States, injury claims about 170,000 lives and results in over 30 million emergency room visits and 2.5 million hospitalizations. Injury is medically defined as organ/tissue damages inflicted upon oneself or by an external agent either accidentally or deliberately. Injury encompasses the undesirable consequences of a wide array of events, such as motor vehicle crashes, poisoning, burns, falls, and drowning, medical error, adverse effects of drugs, suicide and homicide. The past two decades have witnessed a remarkable growth in injury research, both in scope and in depth. To address the tremendous health burden of injury morbidity and mortality at the global level, the World Health Organization in 2000 created the Department of Injury and Violence Prevention, which has produced several influential reports on violence, traffic injury, and childhood injury. The biennial World Conference on Injury Control and Safety Promotion attracts a large international audience and has been successfully convened nine times in different countries. In the United States, the National Center for Injury Prevention and Control became an independent program of the federal Centers for Disease Prevention and Control in 1997. Since then, each state health department has created an office in charge of injury prevention activities and over a dozen universities have established injury control research centers. This volume will fill an important gap in the scientific literature by providing a comprehensive and up-to-date reference resource to researchers, practitioners, and students working on different aspects of the injury problem and in different practice settings and academic fields.


Cardiac Anesthesia

Cardiac Anesthesia

Author: Fawzy G. Estafanous

Publisher: Lippincott Williams & Wilkins

Published: 2001

Total Pages: 1072

ISBN-13: 9780781721950

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The thoroughly updated Second Edition of this highly acclaimed text provides a concise yet comprehensive reference on the clinical and scientific principles of cardiovascular and thoracic anesthesia. The foremost authorities in cardiac anesthesia cover topics particular to this specialized field, such as extracorporeal circulation, transesophageal echocardiography, the physiology and pharmacology of anticoagulation, cardiac catheterization, invasive cardiology, and congenital heart disease. Ideal for residents, fellows, and practicing anesthesiologists, this important text provides comprehensive, practical guidance for all aspects of cardiac anesthesia.


Adult Reconstruction

Adult Reconstruction

Author: Daniel J. Berry

Publisher: Lippincott Williams & Wilkins

Published: 2007

Total Pages: 476

ISBN-13: 9780781796385

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Written by leading experts from the Mayo Clinic, this volume of our Orthopaedic Surgery Essentials Series presents all the information residents need on hip, knee, shoulder, and elbow reconstruction in adults. It can easily be read cover to cover during a rotation or used for quick reference before a patient workup or operation. The user-friendly, visually stimulating format features ample illustrations, algorithms, bulleted lists, charts, and tables. Coverage of each region includes physical evaluation and imaging, evaluation and treatment of disorders, and operative treatment methods. The extensive coverage of operative treatment includes primary and revision arthroplasty and alternatives to arthroplasty.


Yeast Genetics

Yeast Genetics

Author: Jeffrey S. Smith

Publisher: Humana Press

Published: 2014-09-12

Total Pages: 378

ISBN-13: 9781493913640

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Yeast Genetics: Methods and Protocols is a collection of methods to best study and manipulate Saccharomyces cerevisiae, a truly genetic powerhouse. The simple nature of a single cell eukaryotic organism, the relative ease of manipulating its genome and the ability to interchangeably exist in both haploid and diploid states have always made it an attractive model organism. Genes can be deleted, mutated, engineered and tagged at will. Saccharomyces cerevisiae has played a major role in the elucidation of multiple conserved cellular processes including MAP kinase signaling, splicing, transcription and many others. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Yeast Genetics: Methods and Protocols will provide a balanced blend of classic and more modern genetic methods relevant to a wide range of research areas and should be widely used as a reference in yeast labs.


Women at War in the Borderlands of the Early American Northeast

Women at War in the Borderlands of the Early American Northeast

Author: Gina M. Martino

Publisher: UNC Press Books

Published: 2018-03-23

Total Pages: 233

ISBN-13: 1469641003

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Across the borderlands of the early American northeast, New England, New France, and Native nations deployed women with surprising frequency to the front lines of wars that determined control of North America. Far from serving as passive helpmates in a private, domestic sphere, women assumed wartime roles as essential public actors, wielding muskets, hatchets, and makeshift weapons while fighting for their families, communities, and nations. Revealing the fundamental importance of martial womanhood in this era, Gina M. Martino places borderlands women in a broad context of empire, cultural exchange, violence, and nation building, demonstrating how women's war making was embedded in national and imperial strategies of expansion and resistance. As Martino shows, women's participation in warfare was not considered transgressive; rather it was integral to traditional gender ideologies of the period, supporting rather than subverting established systems of gender difference. In returning these forgotten women to the history of the northeastern borderlands, this study challenges scholars to reconsider the flexibility of gender roles and reveals how women's participation in transatlantic systems of warfare shaped institutions, polities, and ideologies in the early modern period and the centuries that followed.


Joint Arthroplasty

Joint Arthroplasty

Author: Shinichi Imura

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 428

ISBN-13: 4431685294

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The introduction of total joint arthroplasty throughout the world has contributed manifold benefits to patients who suffer from joint diseases. Concurrently, however, there has been an increase in revision surgery. Many orthopedic surgeons agree that durability of prostheses is an eternal problem. In particular, periprosthetic osteolysis recently has been identified as one of the serious problems affecting prosthetic dura bility. To improve durability, osteolysis and many other problems must be investi gated and solved both experimentally and clinically with respect to such aspects as prosthetic material, design, and biological and biomechanical behavior. This book comprises 37 papers that were presented by orthopedic surgeons and biomedical engineers at the 28th Annual Meeting of the Japanese Society for Replace ment Arthroplasty, held in March 1998 in Kanazawa, Japan. The volume is thus a compilation of the latest knowledge about the pathogenesis and reduction of osteolysis and wear, newly developed total hip prostheses, and other current topics of total knee arthroplasty. We earnestly hope that this book will be of benefit to clinicians and researchers, and that it will contribute to the creation of more durable total joint prostheses in the future. SHINICHI IMURA v Contents Preface .................... '" .. .. .. ... . .. .. .. . ... .. . . .. . ... . . .. . V List of Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XI . . . . . . . . . . . . Part 1 Wear and Pathogenesis of Osteolysis Friction and Wear of Artificial Joints: A Historical Review N. AKAMATSU ................................................ , 3 Matrix Degradation in Osteoclastic Bone Resorption Under Pathological Conditions .