Read and Download eBook Full
Author: Gordon M. Shepherd
Publisher: Oxford University Press
Published: 2018
Total Pages: 625
ISBN-13: 0190636114
DOWNLOAD EBOOKIn order to focus on principles, each chapter in this work is brief, organized around 1-3 wiring diagrams of the key circuits, with several pages of text that distil the functional significance of each microcircuit
Author: Gordon Shepherd
Publisher: Oxford University Press
Published: 2010-09-22
Total Pages: 535
ISBN-13: 0199780331
DOWNLOAD EBOOKMicrocircuits are the specific arrangements of cells and their connections that carry out the operations unique to each brain region. This resource summarizes succinctly these circuits in over 40 regions - enabling comparisons of principles across both vertebrates and invertebrates. It provides a new foundation for understanding brain function that will be of interest to all neuroscientists. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Author: Sten Grillner
Publisher: MIT Press
Published: 2006
Total Pages: 471
ISBN-13: 0262072785
DOWNLOAD EBOOKLeading neuroscientists discuss the function of microcircuits, functional modules that act as elementary processing units bridging single cells to systems and behavior. Microcircuits, functional modules that act as elementary processing units bridging single cells to systems and behavior, could provide the link between neurons and global brain function. Microcircuits are designed to serve particular functions; examples of these functional modules include the cortical columns in sensory cortici, glomeruli in the olfactory systems of insects and vertebrates, and networks generating different aspects of motor behavior. In this Dahlem Workshop volume, leading neuroscientists discuss how microcircuits work to bridge the single cell and systems levels and compare the intrinsic function of microcircuits with their ion channel subtypes, connectivity, and receptors, in order to understand the design principles and function of the microcircuits. The chapters cover the four major areas of microcircuit research: motor systems, including locomotion, respiration, and the saccadic eye movements; the striatum, the largest input station of the basal ganglia; olfactory systems and the neural organization of the glomeruli; and the neocortex. Each chapter is followed by a group report, a collaborative discussion among senior scientists. Contributors Lidia Alonso-Nanclares, Hagai Bergman, Maria Blatow, J. Paul Bolam, Ansgar Büschges, Antonio Caputi, Jean-Pierre Changeux, Javier DeFelipe, Carsten Duch, Paul Feinstein, Stuart Firestein, Yves Frégnac, Rainer W. Friedrich, C. Giovanni Galizia, Ann M. Graybiel, Charles A. Greer, Sten Grillner, Tadashi Isa, Ole Kiehn, Minoru Kimura, Anders Lanser, Gilles Laurent, Pierre-Marie Lledo, Wolfgang Maass, Henry Markram, David A. McCormick, Christoph M. Michel, Peter Mombaerts, Hannah Monyer, Hans-Joachim Pflüger, Dietmar Plenz, Diethelm W. Richter, Silke Sachse, H. Sebastian Seung, Keith T. Sillar, Jeffrey C. Smith, David L. Sparks, D. James Surmeier, Eörs Szathmáry, James M. Tepper, Jeff R. Wickens, Rafael Yuste
Author: Gordon M. Shepherd
Publisher: Columbia University Press
Published: 2016-11-22
Total Pages: 297
ISBN-13: 0231542879
DOWNLOAD EBOOKIn his new book, Gordon M. Shepherd expands on the startling discovery that the brain creates the taste of wine. This approach to understanding wine's sensory experience draws on findings in neuroscience, biomechanics, human physiology, and traditional enology. Shepherd shows, just as he did in Neurogastronomy: How the Brain Creates Flavor and Why It Matters, that creating the taste of wine engages more of the brain than does any other human behavior. He clearly illustrates the scientific underpinnings of this process, along the way enhancing our enjoyment of wine. Neuroenology is the first book on wine tasting by a neuroscientist. It begins with the movements of wine through the mouth and then consults recent research to explain the function of retronasal smell and its extraordinary power in creating wine taste. Shepherd comprehensively explains how the specific sensory pathways in the cerebral cortex create the memory of wine and how language is used to identify and imprint wine characteristics. Intended for a broad audience of readers—from amateur wine drinkers to sommeliers, from casual foodies to seasoned chefs—Neuroenology shows how the emotion of pleasure is the final judge of the wine experience. It includes practical tips for a scientifically informed wine tasting and closes with a delightful account of Shepherd's experience tasting classic Bordeaux vintages with French winemaker Jean-Claude Berrouet of the Chateau Petrus and Dominus Estate.
Author: and Director NIBS Neuroscience Program University of Southern California Larry W. Swanson Milo Don and Lucille Appleman Professor of Biological Sciences
Publisher: Oxford University Press, USA
Published: 2002-10-23
Total Pages: 283
ISBN-13: 0198026463
DOWNLOAD EBOOKDepending on your point of view the brain is an organ, a machine, a biological computer, or simply the most important component of the nervous system. How does it work as a whole? What are its major parts and how are they interconnected to generate thinking, feelings, and behavior? This book surveys 2,500 years of scientific thinking about these profoundly important questions from the perspective of fundamental architectural principles, and then proposes a new model for the basic plan of neural systems organization based on an explosion of structural data emerging from the neuroanatomy revolution of the 1970's. The importance of a balance between theoretical and experimental morphology is stressed throughout the book. Great advances in understanding the brain's basic plan have come especially from two traditional lines of biological thought-- evolution and embryology, because each begins with the simple and progresses to the more complex. Understanding the organization of brain circuits, which contain thousands of links or pathways, is much more difficult. It is argued here that a four-system network model can explain the structure-function organization of the brain. Possible relationships between neural networks and gene networks revealed by the human genome project are explored in the final chapter. The book is written in clear and sparkling prose, and it is profusely illustrated. It is designed to be read by anyone with an interest in the basic organization of the brain, from neuroscience to philosophy to computer science to molecular biology. It is suitable for use in neuroscience core courses because it presents basic principles of the structure of the nervous system in a systematic way.
Author: Chris Eliasmith
Publisher: Oxford University Press
Published: 2013-04-16
Total Pages: 475
ISBN-13: 0199794693
DOWNLOAD EBOOKHow to Build a Brain provides a detailed exploration of a new cognitive architecture - the Semantic Pointer Architecture - that takes biological detail seriously, while addressing cognitive phenomena. Topics ranging from semantics and syntax, to neural coding and spike-timing-dependent plasticity are integrated to develop the world's largest functional brain model.
Author: Gordon Shepherd
Publisher: Columbia University Press
Published: 2013-07-16
Total Pages: 286
ISBN-13: 0231159110
DOWNLOAD EBOOKLeading neuroscientist Gordon M. Shepherd embarks on a paradigm-shifting trip through the "human brain flavor system," laying the foundations for a new scientific field: neurogastronomy. Challenging the belief that the sense of smell diminished during human evolution, Shepherd argues that this sense, which constitutes the main component of flavor, is far more powerful and essential than previously believed. Shepherd begins Neurogastronomy with the mechanics of smell, particularly the way it stimulates the nose from the back of the mouth. As we eat, the brain conceptualizes smells as spatial patterns, and from these and the other senses it constructs the perception of flavor. Shepherd then considers the impact of the flavor system on contemporary social, behavioral, and medical issues. He analyzes flavor's engagement with the brain regions that control emotion, food preferences, and cravings, and he even devotes a section to food's role in drug addiction and, building on Marcel Proust's iconic tale of the madeleine, its ability to evoke deep memories. Shepherd connects his research to trends in nutrition, dieting, and obesity, especially the challenges that many face in eating healthily. He concludes with human perceptions of smell and flavor and their relationship to the neural basis of consciousness. Everyone from casual diners and ardent foodies to wine critics, chefs, scholars, and researchers will delight in Shepherd's fascinating, scientific-gastronomic adventures.
Author: David J. Linden
Publisher: Yale University Press
Published: 2018-04-24
Total Pages: 399
ISBN-13: 030023547X
DOWNLOAD EBOOKEssays that explore quirky, counterintuitive aspects of brain function and “make us realize that what goes on in our minds is nothing short of magical” (Scientific American). Neuroscientist David J. Linden approached leading brain researchers and asked each the same question: “What idea about brain function would you most like to explain to the world?” Their responses make up this one-of-a-kind collection of popular science essays that seeks to expand our knowledge of the human mind and its possibilities. The contributors, whose areas of expertise include human behavior, molecular genetics, evolutionary biology, and comparative anatomy, address a host of fascinating topics ranging from personality to perception, to learning, to beauty, to love and sex. The manner in which individual experiences can dramatically change our brains’ makeup is explored. Professor Linden and his contributors open a new window onto the landscape of the human mind and into the cutting-edge world of neuroscience with a fascinating, enlightening compilation that science enthusiasts and professionals alike will find accessible and enjoyable. “Scientists who can effectively communicate science are rare, but here are forty of the best, describing with clarity and enthusiasm the latest in brain research and its impact on our lives.” —Gordon M. Shepherd, co-editor of Handbook of Brain Microcircuits
Author: John J. Huang
Publisher: Lippincott Williams & Wilkins
Published: 2012-03-28
Total Pages: 272
ISBN-13: 145114878X
DOWNLOAD EBOOKThe Ocular Inflammatory Disease and Uveitis Manual is a practical, concise clinical reference for resident and practicing ophthalmologists and optometrists treating uveitis patients and an excellent review for the OKAP exam and ophthalmology and optometry boards. Designed for quick point-of-care reference, the book features numerous full-color photographs and bulleted how-to instructions for workup and treatment of each disorder. The state-of-the-art coverage of medical and surgical treatment includes drugs expected to be approved in 2010. The manual is organized into anterior, intermediate, and posterior disease, plus separate sections for corneal and sclera inflammation and infection masquerading syndromes. All topics are further divided into autoimmune and infectious sections, for quick lookup of a disorder.
Author: Edmund T. Rolls
Publisher: Oxford University Press
Published: 2016
Total Pages: 979
ISBN-13: 0198784856
DOWNLOAD EBOOKThis book provides insights into the principles of operation of the cerebral cortex. These principles are key to understanding how we, as humans, function. The book includes Appendices on the operation of many of the neuronal networks described in the book, together with simulation software written in Matlab.
