Green Toxicology
Green Toxicology

Author: Alexandra Maertens

Publisher: Royal Society of Chemistry

Published: 2022-02-01

Total Pages: 225

ISBN-13: 1839164409

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Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.

Green Chemistry Strategies for Drug Discovery
Green Chemistry Strategies for Drug Discovery

Author: Emily A. Peterson

Publisher: Royal Society of Chemistry

Published: 2015-06-30

Total Pages: 338

ISBN-13: 1849739617

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The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Edited by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Currently employed as well as emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery. Moreover, important surrounding issues such as intellectual property are included. This book will serve as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.

Principles and Methods of Toxicology, Fifth Edition
Principles and Methods of Toxicology, Fifth Edition

Author: A. Wallace Hayes

Publisher: CRC Press

Published: 2007-09-25

Total Pages: 2304

ISBN-13: 9780849337789

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Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.

Information Resources in Toxicology
Information Resources in Toxicology

Author: P.J. Bert Hakkinen

Publisher: Academic Press

Published: 2009-08-19

Total Pages: 1553

ISBN-13: 0080920039

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This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the "hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. - International in scope, with contributions from over 30 countries - Numerous key references and relevant Web links - Concise narratives about toxicologic sub-disciplines - Valuable appendices such as the IUPAC Glossary of Terms in Toxicology - Authored by experts in their respective sub-disciplines within toxicology

Clinical Environmental Health and Toxic Exposures
Clinical Environmental Health and Toxic Exposures

Author: John Burke Sullivan

Publisher: Lippincott Williams & Wilkins

Published: 2001

Total Pages: 1348

ISBN-13: 9780683080278

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Now in its revised and updated Second Edition, this volume is the most comprehensive and authoritative text in the rapidly evolving field of environmental toxicology. The book provides the objective information that health professionals need to prevent environmental health problems, plan for emergencies, and evaluate toxic exposures in patients.Coverage includes safety, regulatory, and legal issues; clinical toxicology of specific organ systems; emergency medical response to hazardous materials releases; and hazards of specific industries and locations. Nearly half of the book examines all known toxins and environmental health hazards. A Brandon-Hill recommended title.

Environmental Toxicology and Chemistry
Environmental Toxicology and Chemistry

Author: Donald G. Crosby

Publisher: Oxford University Press on Demand

Published: 1998

Total Pages: 336

ISBN-13: 9780195117134

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Although they are two aspects of the same subject, environmental toxicology and environmental chemistry are usually presented as though they are entirely separate from one another; even their practitioners often seem unaware of the connections. Environmental Toxicology and Chemistry is the first text to tie these subjects closely together, demonstrating the immediate relevance of each subject to the other while also providing basic, easily understandable introductions to both areas. This unique work presents their principles and applications through numerous illustrative examples and special topics that highlight current environmental concerns. It provides up-to-date as well as historical examples of both subjects and includes discussions of ecotoxicology, epidemiology, predictive methods, and other topics not covered in similar texts. It also includes invertebrates and nonmammal vertebrates, plants, and microorganisms, as well as humans and other mammals. The first five chapters place chemicals in the environment; the following five provide the biological and toxicological settings; and the remaining six chapters offer examples of specific chemicals, their toxic effects and significance, and predictions of fate and toxicity. Each chapter concludes with a discussion of a related topic of particular public and scientific interest, such as chemical carcinogens, pesticide residues, or hazardous wastes. Ideal for advanced undergraduate and graduate students in environmental toxicology courses, Environmental Toxicology and Chemistry offers a timely, comprehensive introduction to the principles of toxicology as they apply to our environment. It is also useful for professionals and practitioners in a wide range of environmentally related fields and businesses.

Green Chemistry and Applications
Green Chemistry and Applications

Author: Aide Sáenz-Galindo

Publisher: CRC Press

Published: 2020-11-26

Total Pages: 292

ISBN-13: 1000220087

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Green chemistry is a work tool that can be applied in different areas such as medicine, materials, polymers, food, organic chemistry, etc., since it was propounded in the early 2000s. It has become a viable alternative for care, remediation and protection of the environment and has been implemented worldwide. In this book the twelve principles of green chemistry are presented in a simple way, with examples of the applications of green chemistry in numerous areas showcasing it as an ideal alternative for environmental care. It also provides information on current research being implemented at the pilot plant and industrial level. The book demonstrates the importance of the use of renewable raw materials, the use of catalysis and the implementation of alternative energy sources such as the use of microwaves and ultrasound in different separation and chemical processes.

Toxic Cyanobacteria in Water
Toxic Cyanobacteria in Water

Author: Ingrid Chorus

Publisher: CRC Press

Published: 2021-03-08

Total Pages: 701

ISBN-13: 1000262049

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Cyanobacterial toxins are among the hazardous substances most widely found in water. They occur naturally, but concentrations hazardous to human health are usually due to human activity. Therefore, to protect human health, managing lakes, reservoirs and rivers to prevent cyanobacterial blooms is critical. This second edition of Toxic Cyanobacteria in Water presents the current state of knowledge on the occurrence of cyanobacteria and cyanotoxins as well as their impacts on health through water-related exposure pathways, chiefly drinking-water and recreational activity. It provides scientific and technical background information to support hazard identification, assessment and prioritisation of the risks posed by cyanotoxins, and it outlines approaches for their management at each step of the water-use system. It sets out key practical considerations for developing management strategies, implementing efficient measures and designing monitoring programmes. This enables stakeholders to evaluate whether there is a health risk from toxic cyanobacteria and to mitigate it with appropriate measures. This book is intended for those working on toxic cyanobacteria with a specific focus on public health protection. It intends to empower professionals from different disciplines to communicate and cooperate for sustainable management of toxic cyanobacteria, including public health workers, ecologists, academics, and catchment and waterbody managers. Ingrid Chorus headed the department for Drinking-Water and Swimming-Pool Hygiene at the German Environment Agency. Martin Welker is a limnologist and microbiologist, currently with bioMérieux in Lyon, France.

Living with a Green Heart
Living with a Green Heart

Author: Gay Browne

Publisher: Citadel

Published: 2019-03-26

Total Pages: 290

ISBN-13: 0806539003

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“If you want one of the shortest, fastest routes to getting toxic chemicals out of your life, get behind the wheel of Gay Browne’s Living with a Green Heart and you’ll get there in no time flat.” —Ken Cook, President, Environmental Working Group In an increasingly toxic world, the paths to environmental health and personal well-being run parallel. The journey begins with a few small steps. Is the damage we’re doing to our planet literally leaving you sick, sore, and gasping for air? Want to take back our inalienable rights to clean air, clean water, and healthy food? In this quietly revolutionary book, environmental pioneer and founder of Greenopia, Gay Browne, shares a roadmap for making incremental changes that will not only transform your life, but heal the world we share. From the home to the office, from the foods we eat to the clothes we wear, here are actions you can take today that will improve your Personal Environmental Health, and help you stop feeling overwhelmed, reduce illness, improve sleep, mood, and focus, and start making a difference, including: *Make conscious choices when shopping, and support companies with good environmental stewardship and healthy products. *Test your water for harmful chemicals, install an affordable water filtration system, and reduce your water use by utilizing water more efficiently. *Work with your doctor to create a personal plan for detoxing your body. *Use only non-toxic and organic household products, and choose organic, eco-friendly fabrics made by sustainable and fair trade certified companies. *Choose the method of transportation that makes the lightest carbon footprint. With these and many other actions, Gay Browne’s work has taught her that even the smallest change for the better, faithfully practiced, can have an immense positive impact on our minds, bodies, and spirits—not to mention the planet.