Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-07-02

Total Pages: 287

ISBN-13: 0309132975

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It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.


Sex Itself

Sex Itself

Author: Sarah S. Richardson

Publisher: University of Chicago Press

Published: 2013-12-13

Total Pages: 320

ISBN-13: 022608471X

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Human genomes are 99.9 percent identical—with one prominent exception. Instead of a matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome called the Y. Tracking the emergence of a new and distinctive way of thinking about sex represented by the unalterable, simple, and visually compelling binary of the X and Y chromosomes, Sex Itself examines the interaction between cultural gender norms and genetic theories of sex from the beginning of the twentieth century to the present, postgenomic age. Using methods from history, philosophy, and gender studies of science, Sarah S. Richardson uncovers how gender has helped to shape the research practices, questions asked, theories and models, and descriptive language used in sex chromosome research. From the earliest theories of chromosomal sex determination, to the mid-century hypothesis of the aggressive XYY supermale, to the debate about Y chromosome degeneration, to the recent claim that male and female genomes are more different than those of humans and chimpanzees, Richardson shows how cultural gender conceptions influence the genetic science of sex. Richardson shows how sexual science of the past continues to resonate, in ways both subtle and explicit, in contemporary research on the genetics of sex and gender. With the completion of the Human Genome Project, genes and chromosomes are moving to the center of the biology of sex. Sex Itself offers a compelling argument for the importance of ongoing critical dialogue on how cultural conceptions of gender operate within the science of sex.


The Plasticity of Sex

The Plasticity of Sex

Author: Marianne Legato J

Publisher: Academic Press

Published: 2020-05-20

Total Pages: 318

ISBN-13: 0128159685

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The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior provides a comprehensive view on the development of human sexuality. As there has been a crescendo of interest over the past several decades about the nature and diversity of human sexuality, this reference brings the evidence-based research into one place. The emergence of issues surrounding gender identity, genital ambivalence and the transition from one sex to another is striking, with the public and treating physicians alike clamoring for an evidence-based, comprehensive treatment of human sexuality and all its variations. This is a must-have reference for biomedical researchers in endocrinology, neuroscience, development biology, medical students, residents, and practicing physicians from all medical areas. Winner of the 2021 PROSE Award in Biomedicine from the Association of American Publishers!


Gene Worship

Gene Worship

Author: Gisela T. Kaplan

Publisher: Other Press, LLC

Published: 2003

Total Pages: 312

ISBN-13: 9781590510346

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The authors criticise the new, genetic explanations for human behaviour. They describe the theory of biology, and the reality in which a gendered world and the women's biology and the consequences are described. In the chapter 'Perpetuity' they discuss the gay and queer gene.


Sex Differences in the Brain

Sex Differences in the Brain

Author: Jill B. Becker

Publisher: Oxford University Press

Published: 2007-12-04

Total Pages: 506

ISBN-13: 0198042558

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Within the basic and clinical biomedical research community, there is increasing recognition that differences between males and females across the lifespan affect an individual's health, his/her development of disease, signs and symptoms of pathophysiology, and response to therapy. This book is intended as a resource for scientists, clinicians, and students of the nervous system and behavior- a trove of practical information about how to study sex differences in the brain as well as a discussion of what is already known on the topic.


The Better Half

The Better Half

Author: Sharon Moalem

Publisher: Penguin UK

Published: 2020-04-07

Total Pages: 288

ISBN-13: 0241396905

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An award-winning physician and scientist makes the game-changing case that genetic females are stronger than males at every stage of life 'A powerful antidote to the myth of a "weaker sex"' Gina Rippon, author of The Gendered Brain From birth, genetic females are better at fighting viruses, infections and cancer. They do better at surviving epidemics and famines. They live longer, and even see the world in a wider variety of colours. These are the facts; they are simply stronger than men at every stage of life. Why? And why are we taught the opposite? Drawing on his wide-ranging experience and cutting-edge research as a medic, geneticist and specialist in rare diseases, Dr Sharon Moalem reveals how the answer lies in our genetics: the female's double XX chromosomes offer a powerful survival advantage. And he calls for a long-overdue reconsideration of our one-size-fits-all view of the body and medicine - a view that still frames women through the lens of men. Revolutionary, captivating and utterly persuasive, The Better Half will make you see women, men and the survival of our species anew. 'Brilliant, original and groundbreaking, highly readable and genuinely useful' Daily Mail


The Material Gene

The Material Gene

Author: Kelly E. Happe

Publisher: NYU Press

Published: 2013-05-06

Total Pages: 305

ISBN-13: 0814790690

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Winner of the 2014 Diamond Anniversary Book Award Finalist for the 2014 National Communications Association Critical and Cultural Studies Division Book of the Year Award In 2000, the National Human Genome Research Institute announced the completion of a “draft” of the human genome, the sequence information of nearly all 3 billion base pairs of DNA. Since then, interest in the hereditary basis of disease has increased considerably. In The Material Gene, Kelly E. Happe considers the broad implications of this development by treating “heredity” as both a scientific and political concept. Beginning with the argument that eugenics was an ideological project that recast the problems of industrialization as pathologies of gender, race, and class, the book traces the legacy of this ideology in contemporary practices of genomics. Delving into the discrete and often obscure epistemologies and discursive practices of genomic scientists, Happe maps the ways in which the hereditarian body, one that is also normatively gendered and racialized, is the new site whereby economic injustice, environmental pollution, racism, and sexism are implicitly reinterpreted as pathologies of genes and by extension, the bodies they inhabit. Comparing genomic approaches to medicine and public health with discourses of epidemiology, social movements, and humanistic theories of the body and society, The Material Gene reworks our common assumption of what might count as effective, just, and socially transformative notions of health and disease.


Mean Genes

Mean Genes

Author: Terry Burnham

Publisher: Basic Books

Published: 2012-10-02

Total Pages: 274

ISBN-13: 0465046983

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Short, sassy, and bold, Mean Genes uses a Darwinian lens to examine the issues that most deeply affect our lives: body image, money, addiction, violence, and the endless search for happiness, love, and fidelity. But Burnham and Phelan don't simply describe the connections between our genes and our behavior; they also outline steps that we can take to tame our primal instincts and so improve the quality of our lives. Why do we want (and do) so many things that are bad for us? We vow to lose those extra five pounds, put more money in the bank, and mend neglected relationships, but our attempts often end in failure. Mean Genes reveals that struggles for self-improvement are, in fact, battles against our own genes -- genes that helped our cavewoman and caveman ancestors flourish but that are selfish and out of place in the modern world. Why do we like junk food more than fruit? Why is the road to romance so rocky? Why is happiness so elusive? What drives us into debt? An investigation into the biological nature of temptation and the struggle for control, Mean Genes answers these and other fundamental questions about human nature while giving us an edge to lead more satisfying lives.


Major Sex-Determining Genes

Major Sex-Determining Genes

Author: S. Ohno

Publisher: Springer Science & Business Media

Published: 2013-03-08

Total Pages: 239

ISBN-13: 3642812619

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Upon wresting the control of the earth from the Titans, Zeus assigned the task of creating living creatures to two Titan brothers who had sided with him in the epic battle just concluded. Because Epimetheus, who had been endowed only with hindsight, had the first hand in this creation, all the good attributes were exhaus ted by the time the lion, the elephant and other animals were created. When the time came for the creation of man, there were precious few materials left to work with. Not surprisingly, man was made weak and naked. Prometheus took pity on this miscreation and gave man the use of fire. For this foresight, Zeus meted out horrible punishment, binding Prometheus to a rocky pillar in the Caucasas Moun tains and letting a vulture consume his liver daily. It seems to me that the ancient Greeks in their unfathomable wisdom under stood the essence of the evolutionary process very well. Had Escherichia coli of 200 million years or so ago been endowed with the foresight to anticipate the eventual emergence of and subsequent dominance by mammals of this Earth, they would no doubt have equipped themselves, in anticipation of the coming cer tainty, with the lac operon to deal with lactose in the suckling mammalian infant's gut. Had they been able to do so, the actual emergance of mammals would have exerted no selective pressure upon existing E. COLI.


Gender and Genetics

Gender and Genetics

Author: Kate Reed

Publisher: Routledge

Published: 2012-05-16

Total Pages: 210

ISBN-13: 1135197202

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Prenatal screening for genetic disorders is becoming an increasingly widespread phenomenon across the globe. While studies have highlighted the importance of women’s experiences of such screening, little is known about men’s roles and direct involvement in this process. With a focus on the experiences of both women and men, this text offers an innovative and passionate account of the gendered nature of prenatal screening. Drawing on interview data with pregnant women and their male partners in a UK city, Reed provides a compelling analysis of maternal and paternal roles in prenatal screening. Through this analysis, the book raises important issues around genetics, gender and screening practice. With a focus on the gendered production of ‘good’ and ‘bad’ genes, the book explores differences between visual technologies and blood screening. It also explores the gendered nature of genetic responsibility and the impact this has on parenting roles. Extending its arguments into other key debates in prenatal genetics – including a focus on the impact of screening on other types of stratification, including ethnicity and class – Reed provides an original and comprehensive analysis of some of the most pressing concerns in the field to date. This book will be of interest to students and scholars of the sociology of health and illness, science and technology studies, gender studies, feminist bioethics and medical anthropology, as well as professionals in the fields of midwifery and genetic counselling.