Gasotransmitters: novel regulators of ion channels and transporters

Gasotransmitters: novel regulators of ion channels and transporters

Author: Wolfgang G. Clauss

Publisher: Frontiers E-books

Published: 2013-04-23

Total Pages: 74

ISBN-13: 2889191141

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Gasotransmitters

Gasotransmitters

Author: Rui Wang

Publisher: Royal Society of Chemistry

Published: 2018-06-29

Total Pages: 316

ISBN-13: 1782629246

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Gasotransmitters are gas molecules produced endogenously in prokaryotic and eukaryotic cells for signalling purposes. This book provides, for the first time, a comprehensive description and systematic look at all gasotransmitters, established or proposed, since their detection in 2002. The content and scope covers the production, metabolism, and signalling roles of gasotransmitters. Conceptual advances, scientific discoveries and newly developed techniques described in this book influence our understanding of fundamental molecular and cellular events in biology and medicine. This book serves as the state-of-the-art book for undergraduate and graduate students as well as post-doctoral fellows in biomedical disciplines and toxicologists studying the toxic mechanisms of gasotransmitters in the environment. It will also be welcomed by researchers in university and research institutes, government agencies, pharmaceutical and medical instrument industry, and clinical practice.


The Gastrointestinal System

The Gastrointestinal System

Author: Po Sing Leung

Publisher: Springer Science & Business

Published: 2014-04-29

Total Pages: 370

ISBN-13: 9401787719

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Gastrointestinal (GI) physiology is a fundamental subject that is indispensable not only for undergraduate but also for graduate courses. The audience include, but are not limited to, medical, pharmacy, nursing, human biology, Chinese medicine, and science students, as well as other health-related subject students. The overall objectives of this textbook are to present basic concepts and principles of GI physiology and, more importantly, to convey an understanding of how to apply this knowledge to abnormal GI physiology in the clinical context. As such, the basic knowledge of GI physiology and its application in the form of clinical case studies should be grasped, which are critical for professional examinations and bedside, as well as for general practice in the future. In this handbook, we aim to achieve these elements by covering the breadth of GI, pancreatic, hepatobiliary, and nutritional physiology. Moreover, we include relevant scenario-based clinical case in each chapter so as to evaluate whether the students can apply the basic GI they learn to the clinical setting.


Gasotransmitters Signaling in Plants under Challenging Environment

Gasotransmitters Signaling in Plants under Challenging Environment

Author: Tariq Aftab

Publisher: Springer Nature

Published: 2023-11-25

Total Pages: 331

ISBN-13: 3031430298

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Abiotic stressors, such as drought, extreme temperatures, heavy metals, or high salinity, are causing huge crop losses worldwide. These abiotic stressors are expected to become more extreme, less predictable, and more widespread in the near future. The harm of abiotic stresses includes the disruption of cellular redox homeostasis, reactive oxygen species (ROS) production, and oxidative stress in the plant. Plants have different mechanisms to fight stress, and these mechanisms are responsible for maintaining the required homeostasis in plants. Research on gasotransmitters is rapidly expanding and knowledge regarding the potential of gasotransmitters in biology and medicine is accumulating. Over the past few decades, the roles of these signaling molecules, especially NO and H2S, have been extensively studied for their application in plants. Recently, the emissions of endogenous gasotransmitters in plants have been widely studied and analyzed, thereby providing information to facilitate our understanding of new gasotransmitters signaling pathways. Given the multidimensional role of these signaling molecules, research over the past decades in mitigating abiotic stresses in plant biology and from an agriculture point of view, we intend to bring forth a comprehensive volume “Gasotransmitters Signaling in Plants under Challenging Environment". We are hopeful that this comprehensive volume will furnish the requisite of all those who are working or have an interest in the proposed topic


Signal Transduction and the Gasotransmitters

Signal Transduction and the Gasotransmitters

Author: Rui Wang

Publisher: Springer Science & Business Media

Published: 2004-06-11

Total Pages: 372

ISBN-13: 1592598064

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Gasotransmitters-principally nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)-are endogenous signaling molecules that play a significant role in the biomedical, clinical, and health sciences, as well as in population health studies. In Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine, a panel of distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing their signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels. Included in the array of different mechanisms for the interaction of NO, CO, and H2S are channel phosphorylation, S-nitrosylation, carboxylation, sulfuration, and altered cellular redox status. The authors also offer guidance and suggestions for exploring and further characterizing other still unknown gasotransmitters. Authoritative and comprehensive, Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine offers clinical scientists and physicians not only a deeper understanding, but also a cutting-edge review, of the critically important field of gasotransmitter biology and medicine.


Sulfur Metabolism in Plants

Sulfur Metabolism in Plants

Author: Luit J. De Kok

Publisher: Springer Science & Business Media

Published: 2012-06-19

Total Pages: 276

ISBN-13: 9400744501

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This proceedings volume contains the invited and a selection of the contributed papers of the 8th International Workshop on Sulfur Metabolism in Higher Plants, which was held at Department of Forest and Ecosystem Science, University of Melbourne, Water Street, Creswick, Victoria 3363, Australia from November 22-27, 2010. Content of the volume shows that the understanding of sulfur metabolism in plants and the interaction of the environment are rapidly progressing. This volume covers various aspects of the regulation of sulfate uptake and assimilation in plants, from a cellular to a whole plant level, and additionally emphasizes interactions with other minerals. Moreover the significance of sulfur metabolism in biotic and abiotic stress responses, in food security and quality, and in relation to interactions with global change factors is discussed in detail.


Neuroscience in the 21st Century

Neuroscience in the 21st Century

Author: Donald W. Pfaff

Publisher: Springer

Published: 2016-10-27

Total Pages: 0

ISBN-13: 9781493934737

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Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.


Cell Physiology Source Book

Cell Physiology Source Book

Author: Nicholas Sperelakis

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 1262

ISBN-13: 0080574556

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This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics


Gray's Anatomy E-Book

Gray's Anatomy E-Book

Author: Susan Standring

Publisher: Elsevier Health Sciences

Published: 2021-05-22

Total Pages: 2602

ISBN-13: 0702077070

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Susan Standring, MBE, PhD, DSc, FKC, Hon FAS, Hon FRCS Trust Gray’s. Building on over 160 years of anatomical excellence In 1858, Drs Henry Gray and Henry Vandyke Carter created a book for their surgical colleagues that established an enduring standard among anatomical texts. After more than 160 years of continuous publication, Gray’s Anatomy remains the definitive, comprehensive reference on the subject, offering ready access to the information you need to ensure safe, effective practice. This 42nd edition has been meticulously revised and updated throughout, reflecting the very latest understanding of clinical anatomy from the world’s leading clinicians and biomedical scientists. The book’s acclaimed, lavish art programme and clear text has been further enhanced, while major advances in imaging techniques and the new insights they bring are fully captured in state of the art X-ray, CT, MR and ultrasonic images. The accompanying eBook version is richly enhanced with additional content and media, covering all the body regions, cell biology, development and embryogenesis – and now includes two new systems-orientated chapters. This combines to unlock a whole new level of related information and interactivity, in keeping with the spirit of innovation that has characterised Gray’s Anatomy since its inception. Each chapter has been edited by international leaders in their field, ensuring access to the very latest evidence-based information on topics Over 150 new radiology images, offering the very latest X-ray, multiplanar CT and MR perspectives, including state-of-the-art cinematic rendering The downloadable Expert Consult eBook version included with your (print) purchase allows you to easily search all of the text, figures, references and videos from the book on a variety of devices Electronic enhancements include additional text, tables, illustrations, labelled imaging and videos, as well as 21 specially commissioned ‘Commentaries’ on new and emerging topics related to anatomy Now featuring two extensive electronic chapters providing full coverage of the peripheral nervous system and the vascular and lymphatic systems. The result is a more complete, practical and engaging resource than ever before, which will prove invaluable to all clinicians who require an accurate, in-depth knowledge of anatomy.


Regulation of Coronary Blood Flow

Regulation of Coronary Blood Flow

Author: Michitoshi Inoue

Publisher: Springer Science & Business Media

Published: 2013-11-09

Total Pages: 330

ISBN-13: 4431683674

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Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.