Function and Regulation of Monoamine Enzymes
Author: Earl Usdin
Publisher: Springer
Published: 2015-12-30
Total Pages: 932
ISBN-13: 1349062766
DOWNLOAD EBOOKRead and Download eBook Full
Author: Earl Usdin
Publisher: Springer
Published: 2015-12-30
Total Pages: 932
ISBN-13: 1349062766
DOWNLOAD EBOOKAuthor: Claudia Binda
Publisher: Springer Nature
Published: 2022-09-28
Total Pages: 259
ISBN-13: 1071626434
DOWNLOAD EBOOKThis detailed book examines the main methods to study mammalian monoamine oxidases (MAOs), ranging from cell biology to computational chemistry. Beginning with techniques on how to obtain pure samples of MAO A and MAO B, the volume continues by covering assays and techniques used to measure MAO enzymatic activity and perform inhibition studies, methods to address cellular localization and function of MAOs, either in cell lines or in animal models, as well as computational methods applied to rational drug design approaches that are used to develop new MAO inhibitors. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoamine Oxidase: Methods and Protocols serves as a vital resource for scientists who are interested in studying MAOs and other similar amine oxidase enzymes.
Author: Hajime Yasuhara
Publisher: VSP
Published: 1993-01-01
Total Pages: 260
ISBN-13: 9789067641463
DOWNLOAD EBOOKMonoamine oxidase (MAO), a mitochondrial enzyme which metabolizes monoamines in both the central nervous system and peripheral tissues, plays an important role in the regulation of neuronal activities by controlling the concentrations of monoamines. During the past three decades the enzymological properties of MAO have been studied extensively. The most exciting and important advances in these studies have been the determination of the nucleotide sequence coding two forms of human MAO (MAO-A and MAO-B), and the involvement of MAO in potent dopaminergic neurotoxicity of MPTP, which had led to the acceleration of aetiological studies of Parkinson's disease. Other aspects of MAO studies have been the application of selective and safe MAO inhibitors in the treatment of depression and Parkinson's disease as well as the correlation between MAO and several psychiatric and neurodegenerative disorders.
Author: Thomas Peter Singer
Publisher:
Published: 1979
Total Pages: 576
ISBN-13:
DOWNLOAD EBOOKAuthor: Earl Usdin
Publisher:
Published: 1981
Total Pages: 961
ISBN-13:
DOWNLOAD EBOOKAuthor: Norman Weiner
Publisher: Marcel Dekker
Published: 1977
Total Pages: 1034
ISBN-13:
DOWNLOAD EBOOKAuthor: Earl Usdin
Publisher:
Published: 1981
Total Pages: 0
ISBN-13:
DOWNLOAD EBOOKAuthor: Conference on Structure and Function of Monoamine (1977)
Publisher:
Published: 1977
Total Pages: 996
ISBN-13:
DOWNLOAD EBOOKAuthor: A. J. Sleight
Publisher:
Published: 1988
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor:
Publisher: Academic Press
Published: 2011-10-05
Total Pages: 298
ISBN-13: 0123864682
DOWNLOAD EBOOKPublished since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. In this volume, invited experts provide authoritative reviews on various aspects of Monoamine Oxidase and its Inhibitors. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist