Fibrin Sealant in Operative Medicine
Fibrin Sealant in Operative Medicine

Author: G. Schlag

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 172

ISBN-13: 3642713599

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Fibrin plays a prominent role in wound healing. It has a hemostatic effect, induces cellular response to wound damage, ' and, by forming strands to build a matrix, assists in neovascularization and fibroblast proliferation. The concept of using clotting substances from human blood for wound manage ment and to achieve hemostasis in bleeding parenchymatous organs can be traced to 1909, when Bergel [1] reported on the hemostatic effect of fibrin powder. In 1915, Grey [3] employed fibrin to control bleeding in neurosurgical operations of the brain. A year later, Harvey [4] used fibrin patches to stop bleeding from parenchy matous organs in general surgery. It took more than two decades for this ingenious idea to be rediscovered. In 1940, Young and Medawar [8] reported on experimental nerve anastomosis by sealing. Similarly, Tarlov and Benjamin [7] reunited nerves with plasma clots in 1943. Tarlov improved the results obtained with clot anastomosing of nerves by avoiding tension at the nerve stumps. In 1944, Cronkite et al. [2] reported on an initial series of eight cases in which fibrinogen and thrombin had been used successfully for anchoring skin grafts.

Fibrin Sealing in Surgical and Nonsurgical Fields
Fibrin Sealing in Surgical and Nonsurgical Fields

Author: Günther Schlag

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 323

ISBN-13: 3642792278

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These eight volumes, which developed out of the international congress "Update and Future Trends in Fibrin Sealing in Surgical and Nonsurgical Fields" held in November 1992, present the state of the art in fibrin sealing. Initially, fibrin sealant played an important role in surgery. During the past few years, it has been increasingly applied nonsurgically and we can now say that it has become an integral component of medical treatment. The doubts which have been raised by nonusers about the efficacy of fibrin sealant are no longer valid. The correct indication and technique continue to be basic prerequisites for effective treatment. Even today - 20 years after fibrin sealant was first used - the three most prominent effects of fibrin sealant are still hemostasis, sealing of the wound, and support of wound healing. The problems posed by the transmission of viral infections have gained substantially in importance because of the potential transmission of AIDS via fibrin sealant. Fortunately, this is so unlikely today that it no longer represents a cause for concern, which does not mean, however, that research in this field can be discontinued.

Consultative Hemostasis and Thrombosis E-Book
Consultative Hemostasis and Thrombosis E-Book

Author: Craig S. Kitchens

Publisher: Elsevier Health Sciences

Published: 2013-02-20

Total Pages: 843

ISBN-13: 1455733296

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A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.

Progress in Fibrin Sealing
Progress in Fibrin Sealing

Author: Hans-Werner Waclawiczek

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 237

ISBN-13: 3642483623

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This volume presents the experimental and clinical assessment of fibrin sealing in endoscopy. It is based on a Symposium held in Salzburg, December 1988 and updates information availabe since the first symposium held in Vienna, 1985. Results show that, since fibrin sealing came into clinical use 13 years ago, it has become an accepted tool in many fields of surgery and increased postoperative safety. The indications and limitations of new methods are discussed here, specifically, fibrin sealing for the endoscopic closure of broncho-pleural and gastro-intestinal fistulae, for the endoscopic hemostasis of bleeding gastro-duodenal ulcers, and for the occlusion of the pancreatic duct.

Surgical Adhesives & Sealants
Surgical Adhesives & Sealants

Author: David H. Sierra

Publisher: CRC Press

Published: 2020-03-06

Total Pages: 276

ISBN-13: 1000673219

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Surgical tissue adhesives are an ancient idea, going back to the beginnings of recorded history. The concept of adhering, rather than suturing, packing, or stapling planes of tissue is attractive, in that it is fast-acting and assures complete closure. Numerous technologies have been tried; some with limited success, others outright failures. In short, the perfect adhesive does not exist. Limitations occur in a number of areas: strength, toxicity, degradation, and safety. It is also important to keep in mind that "one size fits all" does not apply to adhesives in surgical applications any more than it does in day-to-day application. As one would not use paper glue to seal a bathtub, one would presumably not apply an adhesive onto tendons, which is suitable for sealing corneas. The properties required of an adhesive for each indication are quite different. Over the last twenty-five years, advances have been made in a wide range of technologies targeting some embodiment of a practical and safe adhesive. Foremost and successful among these are cyanoacrylates, marine adhesive proteins, and fibrin-based sealants. Another promising adhesive technology is laser solders, a mixture of polypeptides and proteoglycans, which integrates with the repair site when laser energy is applied. In light of these advances in the field, the Symposium for Surgical Tissue Adhesives was organized and held at the Atlanta Hyatt from October 8-10, 1993. The goal was to bring together these far-flung technologies in a comprehensive and cohesive manner. Presentations by investigators from around the world described the history of adhesives in medicine, current technologies, laboratory characterizations, and application developments, as well as regulatory aspects and clinical applications. We felt that as many viewpoints as possible, however conflicting, were important to present in order to give the most complete picture of the state of the art of surgical adhesives.

Blood Banking and Transfusion Medicine
Blood Banking and Transfusion Medicine

Author: Christopher D. Hillyer

Publisher: Elsevier Health Sciences

Published: 2006-10-18

Total Pages: 910

ISBN-13: 0702036250

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Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. - Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. - Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics - Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. - Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Pterygium
Pterygium

Author: John Hovanesian

Publisher: CRC Press

Published: 2024-06-01

Total Pages: 184

ISBN-13: 1040142974

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Pterygium surgery often presents a challenge to ophthalmic surgeons due to a high tendency for tissue re-growth. Pterygium: Techniques and Technologies for Surgical Success details the latest advances in ocular surface surgery, as well as new methods to overcome the traditional complications of pterygium surgery. Dr. John A. Hovanesian and his contributors address pterygium surgery through a detailed compilation of intraoperative and postoperative patient management. Pterygium: Techniques and Technologies for Surgical Success includes step-by-step details on a wide range of treatment therapies, such as: • Use of fibrin tissue adhesive • Conjunctival autograft techniques, including wide margin autograft • Amniotic membrane techniques and pearls • Mitomycin and 5FU Adjuncts • Conjunctival Chalasis • Postoperative complications management, including the surgical approach to recurrences Pterygium: Techniques and Technologies for Surgical Success is an indispensible resource for ophthalmic surgeons, residents, fellows, and assisting staff who must keep up with the latest ocular procedures regarding pterygium surgery.

Blood Use in Cardiac Surgery
Blood Use in Cardiac Surgery

Author: N. Friedel

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 317

ISBN-13: 3662061198

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Cardiac surgery has developed dramatically since the first open-he art operations were performed in the mid 1950s. Although the improvement of surgical technique, extracorporeal circulation, and postoperative management has contributed to a marked reduction of morbidity and mortality, the development of cardiac surgery to its present state would not have been possible without blood substitution by homologous donor blood. Only 20 years ago, open-heart operations required an average of 8 units of blood preserves. The excessive need of donor blood in those early days was mainly due to premature surgical technique, insecure control of anticoagulation, severe blood trauma by extracorporeal circulation, and the lack of retransfusion technologies that would have allowed the reuse of shed mediastinal blood. The introduction of new technologies, such as normovolemic hemodilution, in traoperative autotransfusion, postoperative return of shed mediastinal blood, and predonation of autologous blood has greatly reduced donor blood requirements. At present the majority of routine coronary artery surgical procedures can be performed without any blood transfusion. Blood loss, however, may be considerable in patients undergoing complex valve surgery or reoperations, as they often require several units of transfused blood. Blood conservation has now become an area of major interest for the cardiac surgeon. This increased concern is caused by infectious complications of blood transfusion, in particular hepatitis and, more recently, AIDS.

Abdominal Wall Hernias
Abdominal Wall Hernias

Author: Robert Bendavid

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 814

ISBN-13: 1441985743

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Abdominal Wall Hernias is the most up-to-date, comprehensive reference available on all aspects of hernia repair. It includes state-of-the-art approaches to conventional open repairs using tissue-to-tissue techniques, the use of prosthetic mesh, minimally invasive approaches, the repair of recurrent and massive hernias, pertinent anatomy, basic science, and emerging biomaterials. The authors present a full spectrum of procedures to enable readers to gain a broad knowledge of the multifaceted repair of hernias. Richly illustrated, this book is a vital resource for all general surgeons and surgeons-in-training.

Endoscopy
Endoscopy

Author: Günther Schlag

Publisher: Springer Science & Business Media

Published: 2013-11-21

Total Pages: 131

ISBN-13: 3642791654

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The last volume in the series Fibrin Sealing in Surgical and Nonsurgical Fields discusses various uses of fibrin glue in endoscopic surgery. During the last years fibrin sealant has been established in the treatment of gastrointestinal ulcers and esophageal fistulae.