Read and Download eBook Full
Author: Kunlin Jin
Publisher: Bentham Science Publishers
Published: 2010-05-13
Total Pages: 121
ISBN-13: 1608050017
DOWNLOAD EBOOK"This Ebook compiles the efforts of 20 experts in the field to review the latest advances in experimental stroke, with its strong emphasis on neurogenesis, angiogenesis and neuroprotection after cerebral ischemic stroke. It also provides current data for p"
Author: Ulrich Dirnagl
Publisher: Humana Press
Published: 2010-07-08
Total Pages: 0
ISBN-13: 9781607617495
DOWNLOAD EBOOKIn view of the numerous failures of clinical trials aimed at improving stroke therapy, the role and potential benefit of experimentally modeling focal cerebral ischemia in rodents has been debated. When methods of systematic review and metaanalyis are applied, however, it turns out that experimental models actually faithfully predicted the negative outcomes of clinical trials. In addition, thrombolysis and neuroprotection by hypothermia, first described in animal models, are key examples of treatment modalities that have made it successfully into clinical practice. In Rodent Models of Stroke, an international consortium of authors aims at critically addressing the issues on a very practical level, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. The structure and content of the book reflect both the authors’ longstanding expertise in experimental and clinical stroke research and their roles in training the scientific community in the tools of the trade. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used, well-honed approaches in the field today. Stimulating and easy-to-use, Rodent Models of Stroke will help its readers understand the limitations and the opportunities of modeling stroke in rodents and enable them to conduct experiments which will not only improve our understanding of the pathophysiology of this devastating disorder but also serve as the basis for developing new highly effective treatments.
Author: Chung Y. Hsu
Publisher: Karger Medical and Scientific Publishers
Published: 1998
Total Pages: 176
ISBN-13: 3805565607
DOWNLOAD EBOOK'... Provides an admirable review of current knowledge regarding experimental stroke research, and outlines the problems and some solutions in the clinical application of such knowledge.'
Author:
Publisher: ScholarlyEditions
Published: 2013-07-22
Total Pages: 36
ISBN-13: 1481658689
DOWNLOAD EBOOKExperimental Stroke: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Additional Research in a compact format. The editors have built Experimental Stroke: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Experimental Stroke: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Paul A. Lapchak
Publisher: Springer
Published: 2017-01-12
Total Pages: 795
ISBN-13: 3319453459
DOWNLOAD EBOOKA critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. In 5 sections, the proposed volume will explore historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the recent bench-side research.
Author: Paul A. Lapchak
Publisher: Springer
Published: 2017-12-20
Total Pages: 567
ISBN-13: 9811058040
DOWNLOAD EBOOKThis book mainly discusses the current status of stroke transnational research and allows the reader to understand the interplay of common comorbidities in the stroke population such as diabetes and hypertension, and provides insight into stroke targets to promote cell survival, angiogenesis, neurogenesis, and most importantly, functional recovery after stroke. Throughout the world, stroke is still a leading cause of mortality and morbidity; each year approximately 15 million people worldwide suffer from stroke. Stroke is now the leading cause of death and disability in China. Large communities of stroke survivors are eagerly awaiting scientific advances in transnational stroke research that would offer neuroprotective therapeutics for acute stroke management, or rehabilitation and regenerative strategies utilizing novel stem cell-based approaches. While research is ongoing, the Editors have compiled this volume to help the further understanding of the pathophysiology of stroke and to review and identify future potential biomarkers. The book is written for students, researchers and physicians in neurosciences, neurology and neuroradiology.
Author: Paul A. Lapchak
Publisher: Springer Science & Business Media
Published: 2012-03-23
Total Pages: 926
ISBN-13: 1441995293
DOWNLOAD EBOOKThis volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.
Author: Amit Kumar Tripathi
Publisher: Springer Nature
Published: 2021-03-30
Total Pages: 115
ISBN-13: 9813366796
DOWNLOAD EBOOKThis book summarizes various tools and techniques used to provide insights into the cellular and molecular pathophysiology of stroke. It also presents rodent animal models to help shed light on the pathophysiology of ischemic stroke. Presenting the latest information on the different types of stroke, including embolic, filament, photothrombotic, and bilateral common carotid artery, the book also describes techniques that are used for confirmation of stroke surgery, such as laser speckle imaging (LSI) and laser Doppler flowmetry (LDF), and discusses the non-human primates that are used in stroke surgery, cerebral venous sinuous thrombosis, and neurobehavioral assessment. Lastly, it analyzes various neuroprotective agents to treat and prevent ischemic stroke, and examines the challenges and advances in treating and preventing acute ischemic stroke.
Author: Hugh S. Markus
Publisher: Oxford Medical Publications
Published: 2003
Total Pages: 362
ISBN-13: 0198515863
DOWNLOAD EBOOKStroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
Author:
Publisher: ScholarlyEditions
Published: 2013-07-22
Total Pages: 51
ISBN-13: 148166493X
DOWNLOAD EBOOKExperimental Stroke: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Additional Research in a compact format. The editors have built Experimental Stroke: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Experimental Stroke: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
