Experimental Developmental Biology

Experimental Developmental Biology

Author: Laura R. Keller

Publisher: Academic Press

Published: 1999

Total Pages: 130

ISBN-13: 9780124039704

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This work is designed for use as a lab manual in college-level courses in developmental biology or animal development. In each exercise, students examine gametes and developing embryos of a single species, and also perform several experiments to probe its developmental process.


Key Experiments in Practical Developmental Biology

Key Experiments in Practical Developmental Biology

Author: Manuel Marí-Beffa

Publisher: Cambridge University Press

Published: 2005-03-24

Total Pages: 412

ISBN-13: 9780521833158

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Originally published in 2005, this unique resource presents 27 easy-to-follow laboratory exercises for use in student practical classes in developmental biology. These experiments provide key insights into developmental questions, and many of them are described by the leaders in the field who carried out the original research. This book intends to bridge the gap between experimental work and the laboratory classes taken at the undergraduate and post-graduate levels. All chapters follow the same format, taking the students from materials and methods, through results and discussion, so that they learn the underlying rationale and analysis employed in the research. The book will be an invaluable resource for graduate students and instructors teaching practical developmental biology courses. Chapters include teaching concepts, discussion of the degree of difficulty of each experiment, potential sources of failure, as well as the time required for each experiment to be carried out in a class with students.


Experimental Design for Biologists

Experimental Design for Biologists

Author: David J. Glass

Publisher: CSHL Press

Published: 2007

Total Pages: 211

ISBN-13: 0879697350

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The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.


Laboratory Exercises in Developmental Biology

Laboratory Exercises in Developmental Biology

Author: Yolanda P. Cruz

Publisher: Academic Press

Published: 2012-12-02

Total Pages: 254

ISBN-13: 0323137776

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This intensive manual provides students with valuable information and insights into animal development at the organismal, cellular, and subcellular levels. The book uses both descriptive and investigative approaches that emphasize techniques, key experiments, and data analysis. - Provides a broad introductory view of developmental systems - Teaches both classical embryology and modern experimental approaches - Contains seventeen laboratory exercises, written in step-by-step style - Organized with additional notes to students and preparators - Lists questions and references for each exercise - Special chapters give introductions to the scientific process, use of the microscope, and the writing of scientific papers - Illustrated with detailed line drawings


Experiments in Molecular Biology

Experiments in Molecular Biology

Author: Robert J. Slater

Publisher: Springer Science & Business Media

Published: 1986-07-08

Total Pages: 386

ISBN-13: 0896030822

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Text clean and bright, binding tight, only flaw is a blank bookplate from a chemical company pasted on the front free endpaper."" An excellent experimental guide to molecular biology, offering detailed protocols ranging from chemical to microbiological methods. The format is sufficiently versatile to serve either a short workshop or a full academic year biochemistry laboratory. Each of the 25 experiments included is presented in a chapter with background information, a list of materials the experimenter will encounter, a detailed protocol, information needed to interpret and discuss the result.


Dynamics of Development: Experiments and Inferences

Dynamics of Development: Experiments and Inferences

Author: Paul A. Weiss

Publisher: Academic Press

Published: 2013-09-17

Total Pages: 639

ISBN-13: 1483270602

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Dynamics of Development: Experiments and Inferences provides an understanding of the dynamic order of living systems. This book presents a methodical approach to the unrestricted exploration of all the aspects that a living system offers, which is evaluated logically through experiment and inference. Organized into five parts encompassing 24 chapters, this book begins with an overview of the adaptive features of the nervous system. This text then examines the molecular control of cellular activity. Other chapters focus on resolving the fragments of the chemical endowment of the cell. This book discusses as well the mechanisms of respiration and photosynthesis, which have been connected with arrays of macromolecular complexes in definite sequential order. The final chapter deals with the fundamental principle of neural intercommunication. This book is a valuable resource for biochemists, biologists, zoologists, neurophysiologists, and scientists. Students and research workers interested in the dynamic order of living systems will also find this book useful.


Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Author: National Research Council

Publisher: National Academies Press

Published: 2000-12-21

Total Pages: 348

ISBN-13: 0309070864

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Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.


Landmark Experiments in Molecular Biology

Landmark Experiments in Molecular Biology

Author: Michael Fry

Publisher: Academic Press

Published: 2016-06-10

Total Pages: 572

ISBN-13: 012802108X

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Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. - Includes detailed analysis of classically designed and executed experiments - Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries - Provides critical analysis of the history of molecular biology to inform the future of scientific discovery - Examines the machinery of inheritance and biological information handling


The Molecular Biology of Cell Determination and Cell Differentiation

The Molecular Biology of Cell Determination and Cell Differentiation

Author: Leon W. Browder

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 448

ISBN-13: 146156817X

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This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, which is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is comprised of chapters selected to provide the conceptual basis for a comprehensive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of developmental biology should understand the experimental back ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful. The creative process then generates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery.