Evaluation of Immunoassay Methods for Prolactin in Body Fluids

Evaluation of Immunoassay Methods for Prolactin in Body Fluids

Author: D. A. Dilley

Publisher:

Published: 1966

Total Pages: 36

ISBN-13:

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A practical immunologic assay to detect the hormone, prolactin, in body fluids was evaluated. Prolactin content was assayed using positive antiprolactin sera prepared in rabbits and test samples of serum, urine, and urinary extract from a borane exposed female monkey in micro-Ouchterlony gel diffusion and agglutination inhibition tests. The gel diffusion test gave qualitative results while the agglutination inhibition test allowed quantitation of prolactin content. Results of the later test indicated a possible difference in pre- and postborane exposure prolactin content of monkey urine. Further work in this area will need to be done to clarify this preliminary evidence and to expand on its applicability to human exposure to boranes.


Knobil and Neill's Physiology of Reproduction

Knobil and Neill's Physiology of Reproduction

Author: Ernst Knobil

Publisher: Gulf Professional Publishing

Published: 2006

Total Pages: 1780

ISBN-13: 9780125154017

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The 3rd edition, the first new one in ten years, includes coverage of molecular levels of detail arising from the last decade's explosion of information at this level of organismic organization. There are 5 new Associate Editors and about 2/3 of the chapters have new authors. Chapters prepared by return authors are extensively revised. Several new chapters have been added on the topic of pregnancy, reflecting the vigorous investigation of this topic during the last decade.The information covered includes both human and experimental animals; basic principels are sought, and information at the organismic and molecular levels are presented. *The leading comprehensive work on the physiology of reproduction*Edited and authored by the world's leading scientists in the field*Is a synthesis of the molecular, cellular, and organismic levels of organization*Bibliogrpahics of chapters are extensive and cover all the relevant literature


Prolactin: Physiology and Clinical Significance

Prolactin: Physiology and Clinical Significance

Author: D.F. Horrobin

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 245

ISBN-13: 9401096953

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I first became interested in prolactin a little over two years ago. I was then working in Nairobi and I knew nothing about the hormone apart from its role in lactation. Professor Mohammed Hyder of the Department of Zoology in the University of Nairobi was interested in the endocrine mechanisms which enable Tilapia fish to adapt to water with a very high electrolyte content. He invited me to a seminar given by Professor Howard Bern which was largely concerned with the role prolactin plays in fluid and electrolyte balance in sub-mammalian vertebrates. This inspired me to begin a programme of research into the roles prolactin plays in man and other animals. Very few physiologists or clinicians seem aware of the multifarious effects of prolactin in mammals. This book therefore aims to give a comprehensive account of the mammalian physiology of prolactin and to make suggestions about its possible role in diseases ranging from cancer to mental illness. The two subjects which have been previously widely covered, the roles of prolactin in lactation and in rat mammary cancer, are presented relatively briefly though with a full list of references. Other subjects are dealt with more extenSively and I hope that many research workers and clinicians may find the book helpful.