Ending Medical Reversal

Ending Medical Reversal

Author: Vinayak K. Prasad

Publisher: Johns Hopkins University Press

Published: 2019-05-14

Total Pages: 276

ISBN-13: 1421429047

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Why medicine adopts ineffective or harmful medical practices only to abandon them—sometimes too late. Medications such as Vioxx and procedures such as vertebroplasty for back pain are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients. In Ending Medical Reversal, Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors' offices and hospitals is truly effective.


Malignant

Malignant

Author: Vinayak K. Prasad

Publisher: Johns Hopkins University Press

Published: 2020-04-21

Total Pages: 304

ISBN-13: 1421437635

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This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer—and how we can avoid repeating the policy and practice mistakes of the past.


The End of Alzheimer's

The End of Alzheimer's

Author: Dale Bredesen

Publisher: Penguin

Published: 2017-08-22

Total Pages: 322

ISBN-13: 0735216207

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The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.


Ending Aging

Ending Aging

Author: Aubrey de Grey

Publisher: Macmillan + ORM

Published: 2007-09-04

Total Pages: 452

ISBN-13: 1429931833

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MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.


The Danger Within Us

The Danger Within Us

Author: Jeanne Lenzer

Publisher: Little, Brown

Published: 2017-12-12

Total Pages: 306

ISBN-13: 0316343781

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Did you know... Medical interventions have become the third leading cause of death in America. An estimated 10 percent of Americans are implanted with medical devices -- like pacemakers, artificial hips, cardiac stents, etc. The overwhelming majority of high-risk implanted devices have never undergone a single clinical trial. In The Danger Within Us, award-winning journalist Jeanne Lenzer brings these horrifying statistics to life through the story of one working class man who, after his "cure" nearly kills him, ends up in a battle for justice against the medical establishment. His crusade leads Lenzer on a journey through the dark underbelly of the medical device industry, a fascinating and disturbing world that hasn't been written about before. What Lenzer exposes will shock readers: rampant corruption, elaborate cover-ups, shameless profiteering, and astonishing lack of oversight, all of which leads to dangerous devices (from artificial hips to pacemakers) going to market and into our bodies. In the vein of America's Bitter Pill and A Civil Action, The Danger Within Us is a stirring call for reform and a must-read for anyone who cares about the future of American healthcare. "Before you get anything implanted in your body, read this book."-Shannon Brownlee, author of Overtreated


The End of Diabetes

The End of Diabetes

Author: Joel Fuhrman, M.D.

Publisher: Harper Collins

Published: 2012-12-26

Total Pages: 258

ISBN-13: 0062219995

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The New York Times bestselling author of Eat to Live and Super Immunity and one of the country’s leading experts on preventive medicine offers a scientifically proven, practical program to prevent and reverse diabetes—without drugs. At last, a breakthrough program to combat the rising diabetes epidemic and help millions of diabetics, as well as those suffering with high blood pressure and heart disease. Joel Fuhrman, M.D. Research director of the Nutritional Research Foundation, shows you how to live a long, healthy, and happy life—disease free. He offers a complete health transformation, starting with a diet with a high nutrient-per-calorie ratio that can be adapted for individual needs. Dr. Fuhrman makes clear that we don’t have to “control” diabetes. Patients can choose to follow better nutritional guidelines that will control it for them, even before they have lost excess weight. The end result is a medical breakthrough—a comprehensive reversal of the disease.


10 Things I Wish I’d Learned in Medical School

10 Things I Wish I’d Learned in Medical School

Author: A.J. Seiffertt D.O.

Publisher: Balboa Press

Published: 2019-04-29

Total Pages: 253

ISBN-13: 1982225254

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This book is a practical guide to practicing sustainable health and medicine, and is a must read for anyone interested in building their understanding of their own health, the current healthcare system, and the health of our shared planet. Each chapter includes information about topics such as our microbiome, sleep patterns, food, sustainable farming, exercise, meditation, and preparing for the end of life. Every step of the way there are practical suggestions about how people of all ages can start to be more proactive about their health, encouraging sustainable practices and policies across social and economic strata. These ideas from Dr. Seiffertt’s Osteopathic Internal Medicine practice are helpful no matter what stage of life or health you find yourself in, whether you have just been diagnosed with cancer, a chronic illness like diabetes, or simply don’t feel as healthy as you might: living in greater health is always possible.


Malignant

Malignant

Author: Vinayak K. Prasad

Publisher: JHU Press

Published: 2020-04-21

Total Pages: 304

ISBN-13: 1421437643

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How hype, money, and bias can mislead the public into thinking that many worthless or unproven treatments are effective. Each week, people read about new and exciting cancer drugs. Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel—but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which • promote novel cancer therapies long before credible data are available to support such treatment; and • exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars. Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration. This is a book about how the actions of human beings—our policies, our standards of evidence, and our drug regulation—incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says, • more cancer clinical trials should measure outcomes that actually matter to people with cancer; • patients on those trials should look more like actual global citizens; • we need drug regulators to raise, not perpetually lower, the bar for approval; and • we need unbiased patient advocates and experts. This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer—and how we can avoid repeating the policy and practice mistakes of the past.


Evidence-biased Antidepressant Prescription

Evidence-biased Antidepressant Prescription

Author: Michael P. Hengartner

Publisher: Springer Nature

Published: 2021-12-09

Total Pages: 355

ISBN-13: 3030825876

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This book addresses the over-prescribing of antidepressants in people with mostly mild and subthreshold depression. It outlines the steep increase in antidepressant prescription and critically examines the current scientific evidence on the efficacy and safety of antidepressants in depression. The book is not only concerned with the conflicting views as to whether antidepressants are useful or ineffective in various forms of depression, but also aims at detailing how flaws in the conduct and reporting of antidepressant trials have led to an overestimation of benefits and underestimation of harms. The transformation of the diagnostic concept of depression from a rare but serious disorder to an over-inclusive, highly prevalent but predominantly mild and self-limiting disorder is central to the books argument. It maintains that biological reductionism in psychiatry and pharmaceutical marketing reframed depression as a brain disorder, corroborating the overemphasis on drug treatment in both research and practice. Finally, the author goes on to explore how pharmaceutical companies have distorted the scientific literature on the efficacy and safety of antidepressants and how patient advocacy groups, leading academics, and medical organisations with pervasive financial ties to the industry helped to promote systematically biased benefit-harm evaluations, affecting public attitudes towards antidepressants as well as medical education, training, and practice.


Enchanted America

Enchanted America

Author: J. Eric Oliver

Publisher: University of Chicago Press

Published: 2018-09-18

Total Pages: 279

ISBN-13: 022657864X

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America is in civic chaos, its politics rife with conspiracy theories and false information. Nationalism and authoritarianism are on the rise, while scientists, universities, and news organizations are viewed with increasing mistrust. Its citizens reject scientific evidence on climate change and vaccinations while embracing myths of impending apocalypse. And then there is Donald Trump, a presidential candidate who won the support of millions of conservative Christians despite having no moral or political convictions. What is going on? The answer, according to J. Eric Oliver and Thomas J. Wood, can be found in the most important force shaping American politics today: human intuition. Much of what seems to be irrational in American politics arises from the growing divide in how its citizens make sense of the world. On one side are rationalists. They use science and reason to understand reality. On the other side are intuitionists. They rely on gut feelings and instincts as their guide to the world. Intuitionists believe in ghosts and End Times prophecies. They embrace conspiracy theories, disbelieve experts, and distrust the media. They are stridently nationalistic and deeply authoritarian in their outlook. And they are the most enthusiastic supporters of Donald Trump. The primary reason why Trump captured the presidency was that he spoke about politics in a way that resonated with how Intuitionists perceive the world. The Intuitionist divide has also become a threat to the American way of life. A generation ago, intuitionists were dispersed across the political spectrum, when most Americans believed in both God and science. Today, intuitionism is ideologically tilted toward the political right. Modern conservatism has become an Intuitionist movement, defined by conspiracy theories, strident nationalism, and hostility to basic civic norms. Enchanted America is a clarion call to rationalists of all political persuasions to reach beyond the minority and speak to intuitionists in a way they understand. The values and principles that define American democracy are at stake.