The account in this inaugural volume of the series covers the period 1900 to 1960, but also outlines the principal developments in earlier centuries from which biochemistry emerged. Findings are considered in the light of present knowledge, rather than in a rigid historical framework.
This fourth volume in the series on biochemistry looks at foundations in modern biochemistry. Topics covered include: the genetic solution; the genetic basis of development; DNA repair; evolution in an RNA world; nitrogen fixation; solute channels; viruses; biochemistry in retrospect and propspect.
Biochemistry Second Edition, is a single-semester text designed for undergraduate non-biochemistry majors. Accessible, engaging, and informative, it is the perfect introduction to the subject for students who may approach chemistry with apprehension. Its unique emphasis on metabolism and its kinetic underpinnings gives the text up-to-the-minute relevance for students investigating current public health concerns, such as obesity and diabetes. Biochemistry Second Edition will encourage students to explore the basics of chemistry and its influence on biological problems. Key Features: Provides an understanding of (mostly) enzymatic reactions that are responsible for the function and maintenance of living things. This innovative text for non-biochemistry majors includes introductory material at the beginning of each chapter that contextualizes chapter themes in real-life scenarios. Online supporting materials with further opportunities for research and investigation. Synthesis questions at the end of each chapter that encourage students to make connections between concepts and ideas, as well as develop critical-thinking skills. About the Author: Raymond S. Ochs is a biochemist with a career-long specialty in metabolism spanning 30 years. Previously, he has written the textbook Biochemistry, contributed the metabolism chapters to another text, Principles of Biochemistry, and co-edited a collection of articles published as Metabolic Regulation, and the recent monograph Metabolic Strucure and Regulation. His research interests concern major pathways of liver and muscle, including glycolysis, gluconeogenesis, ureogenesis, fatty acid metabolism, glycogen metabolism, and control by cAMP, Ca2+, diacylglycerol, and AMPK. He is currently professor of pharmacy at St. John’s University in New York, teaching biochemistry, physiology, and medicinal chemistry.
This volume covers such quantum leaps in the field of biochemistry as the coding properties of DNA and the central dogma, manipulating DNA, extranuclear DNA, protein synthesis and the ribosome, and cell cycles.
"Provides an in-depth review of current print and electronic tools for research in numerous disciplines of biology, including dictionaries and encyclopedias, method guides, handbooks, on-line directories, and periodicals. Directs readers to an associated Web page that maintains the URLs and annotations of all major Inernet resources discussed in th
From New York Times bestselling author Sam Kean comes incredible stories of science, history, finance, mythology, the arts, medicine, and more, as told by the Periodic Table. Why did Gandhi hate iodine (I, 53)? How did radium (Ra, 88) nearly ruin Marie Curie's reputation? And why is gallium (Ga, 31) the go-to element for laboratory pranksters? The Periodic Table is a crowning scientific achievement, but it's also a treasure trove of adventure, betrayal, and obsession. These fascinating tales follow every element on the table as they play out their parts in human history, and in the lives of the (frequently) mad scientists who discovered them. The Disappearing Spoon masterfully fuses science with the classic lore of invention, investigation, and discovery -- from the Big Bang through the end of time. Though solid at room temperature, gallium is a moldable metal that melts at 84 degrees Fahrenheit. A classic science prank is to mold gallium spoons, serve them with tea, and watch guests recoil as their utensils disappear.
Healing and Wholeness: Complementary and Alternative Therapies for Mental Health provides a comprehensive overview of complementary and alternative treatments for mental health, with information and research on their effectiveness for treating specific disorders. Twenty-two chapters document research and the current practice of using complementary and alternative therapies in treating a number of disorders, including depression, anxiety, ADHD, autism, and addictions. The therapies covered are both state-of-the-art and ancient, including naturopathy, psychotherapy, hypnotherapy, nutritional therapy, herbal medicine, meditation, and others. Each chapter begins with a description of the classification of the disorder, followed by discussions of scientific documentation on diet, nutritional therapy, herbal medicine, complementary and alternative therapies, psychotherapy, and lifestyle changes. This compendium of integrative and holistic therapies provides the reader with access to a multitude of options for improving their mental health. This is a thorough guide to alternative therapies in the mental health field, organizing a large amount of information in a relevant, easy-to-use format. Healing and Wholeness: Complementary and Alternative Therapies for Mental Health can be used as a standard reference for the mental health care professional, the graduate student, or anyone looking to improve their emotional health. To learn more about Healing and Wholeness: Complementary and Alternative Therapies for Mental Health and to read excerpts, visit www.HealingandWholeness.org.
There is a renewed interest in the fundamentals of energy metabolism, yet most people base their understanding on the views of generalists expressed in elementary textbooks. New techniques that enable analysis of thousands of metabolites provide useful data, but do not themselves substitute for an understanding of the fundamentals of metabolism. While classical ideas of metabolism are also valuable, some earlier ideas have not withstood further investigation. This book presents a personal philosophy but rests on what is broadly accepted by metabolic biochemists over the past few decades.
Like any goal-oriented procedure, experiment is subject to many kinds of failures. These failures have a variety of features, depending on the particulars of their sources. For the experimenter these pitfalls should be avoided and their effects minimized. For the historian-philosopher of science and the science educator, on the other hand, they are instructive starting points for reflecting on science in general and scientific method and practice in particular. Often more is learned from failure than from confirmation and successful application. The identification of error, its source, its context, and its treatment shed light on both practices and epistemic claims. This book shows that it is fruitful to bring to light forgotten and lost failures, subject them to analysis and learn from their moral. The study of failures, errors, pitfalls and mistakes helps us understand the way knowledge is pursued and indeed generated. The book presents both historical accounts and philosophical analyses of failures in experimental practice. It covers topics such as "error as an object of study", "learning from error", "concepts and dead ends", "instrumental artifacts", and "surprise and puzzlement". This book will be of interest to historians, philosophers, and sociologists of science as well as to practicing scientists and science educators.
Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. - Provides a fully-updated resource with more color illustrations - Focuses on the biochemical and molecular basis of disease as well as the analytical techniques - Defines important differences in the pathophysiology of diseases, comparing childhood with adult