Dysregulation of Autonomic Cardiac Control by Traumatic Stress and Anxiety

Dysregulation of Autonomic Cardiac Control by Traumatic Stress and Anxiety

Author: J. P. Ginsberg

Publisher: Frontiers Media SA

Published: 2016-08-05

Total Pages: 120

ISBN-13: 2889199150

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Current understanding of the interplay between sympathetic and parasympathetic influences on cardiac response to environmental stimuli and subsequent response selection (e.g. maintenance of resting homeostasis, mobilization of defensive response, task performance, tonic immobilization, and/or affiliation) will be explored. Reference will be made to how these processes conjoin with proposed polyvagal theory. Cardiac adjustments to environmental stimuli affect the internal physiological state of the organism as well as the quality of information processing that the individual can perform during the stimulus appraisal stage of the orienting response. Bradyrdia is adaptive in early stages of orientation to novel or potential threat, while greater HRV power serves to facilitate self-regulation, stimulus information processing and appraisal, and appropriate response selection. This issue is devoted to current research findings on how normal patterns of cardiac autonomic regulation of HRV are disrupted in PTSD, impairing sustained attention to the environment and increasing the rate of inappropriate responding to stimuli. Origins of our current state of understanding in the ‘intake-rejection’ hypothesis will be considered, and how the intake-rejection hypothesis has morphed into present-day Optimal Performance practice. Additionally, empirical data where available will be presented on how dysregulation of the normal pattern of cardiac autonomic regulation by PTSD impairs sustained attention to the environment, and increases the rate of inappropriate responding to stimuli through disinhibition, poor impulse control, emotional withdrawal, over-arousal, and attentional bias. Current research findings are sought that address in controlled, experimental and clinical trials the restorative effects of HRV biofeedback on HRV power, and how increases in HRV power relate to improved attention / immediate memory and self-regulation of affect using outcome measures of cognition, symptoms of PTSD and depression, stress perception, and level of adaptive function.


Pituitary Adenylate Cyclase-Activating Polypeptide

Pituitary Adenylate Cyclase-Activating Polypeptide

Author: Hubert Vaudry

Publisher: Springer Science & Business Media

Published: 2003

Total Pages: 432

ISBN-13: 9781402073069

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Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.


Neurobiology of Panic Disorder

Neurobiology of Panic Disorder

Author: James C. Ballenger

Publisher: Wiley-Liss

Published: 1990-02-07

Total Pages: 424

ISBN-13:

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Leading international experts emphasize that the ultimate understanding of panic disorder as a multifaceted clinical syndrome will involve multiple viewpoints and research approaches. Their contributions to Neurobiology of Panic Disorder offer such necessarily varied perspectives. Featuring vital data obtained over the last five years, this informative volume covers the neurobiological aspects of panic disorder, with an emphasis on mechanistic and preclinical studies. Contributions include a wide range of pertinent topics such as preclinical studies of brain systems involved in anxiety, familial and genetic marker studies, potential childhood antecedents of panic disorder, and animal models of anxiety. In addition, an examination of the noradrenergic system, viewpoints on the pathogenesis, pathophysiology and treatment potential of the serotonin system, and coverage of commonly used brain imaging techniques in research and clinical evaluation are included in the text.


Functional Somatic Symptoms in Children and Adolescents

Functional Somatic Symptoms in Children and Adolescents

Author: Kasia Kozlowska

Publisher: Springer Nature

Published: 2020-09-30

Total Pages: 397

ISBN-13: 303046184X

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This open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.


Annual Review of Cybertherapy and Telemedicine

Annual Review of Cybertherapy and Telemedicine

Author: B. K. Wiederhold

Publisher: IOS Press

Published: 2010

Total Pages: 256

ISBN-13: 1607505606

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This book offers support and encouragement to all those interested in the development of cybertherapy systems. It provides evidence to build confidence in their effectiveness for detecting, monitoring and evaluating a number of important conditions and identifies and addresses the main barriers to their further development. It is divided into four main sections: critical reviews, evaluation studies, original research and clinical observations, tackling this complex subject by means of a clearly sequenced structure. --


APA Handbook of Trauma Psychology

APA Handbook of Trauma Psychology

Author: Steven N. Gold

Publisher: APA Handbooks in Psychology(r)

Published: 2017-04

Total Pages: 1168

ISBN-13: 9781433826535

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The two volume APA Handbook of Trauma Psychology is the most comprehensive guide and reference work on the subject to date. It provides a survey of all the major areas and subtopics of empirical knowledge and practical applications in the field of trauma psychology, written by top experts in the field. Volume 1 is divided into sections on the nature of trauma, its psychological impact, major conceptual frameworks for understanding traumatization, and trauma as viewed from the diverse perspective of various disciplines. Volume 2 covers multiple applications of trauma psychology, including various modalities of trauma assessment, major treatment approaches across the lifespan, and multiclient and organizational practice. The APA Handbook of Trauma Psychology is an essential resource for specialists in trauma who need comprehensive information, for practitioners who seek to familiarize themselves with the range of approaches for trauma assessment and treatment, and for students as a graduate level or advanced undergraduate level textbook.


Autonomic Neurology

Autonomic Neurology

Author: Eduardo E. Benarroch

Publisher: Oxford University Press

Published: 2014-04-03

Total Pages: 314

ISBN-13: 0199920206

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The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.


Magnesium in the Central Nervous System

Magnesium in the Central Nervous System

Author: Robert Vink

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 354

ISBN-13: 0987073052

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The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.


Stress and Cardiovascular Disease

Stress and Cardiovascular Disease

Author: Paul Hjemdahl

Publisher: Springer Science & Business Media

Published: 2011-10-01

Total Pages: 389

ISBN-13: 184882419X

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The main aim of this book is to evaluate the concept of stress and provide tools for physicians to identify patients who might benefit from stress management. This will incorporate a detailed description of the physiological and pathophysiological consequences of acute and chronic stress that might lead to cardiovascular disease. The book will aim to critically evaluate interventional research (behavioural and other therapies) and provide evidence based recommendations on how to manage stress in the cardiovascular patient. Our intentions are to define and highlight stress as an etiological factor for cardiovascular disease, and to describe an evidence based "tool box" that physicians may use to identify and manage patients in whom stress may be an important contributing factor for their disease and their risk of suffering cardiovascular complications.