Drugs from the Sea
Drugs from the Sea

Author: Nobuhiro Fusetani

Publisher: Karger Medical and Scientific Publishers

Published: 2000-01-01

Total Pages: 164

ISBN-13: 3805570988

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The present book consists of three parts: discovery, development and production of drugs from marine organisms. Marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks have attracted much attention as sources of potential drugs, which is described in the first part. A pain-killing drug developed from the venom of a cone shell is a recent highlight of marine natural product research; the interesting story of its discovery is provided. The second part features an anticancer drug with a novel mode of action which was originally isolated from a songe and a potential antiosteoporotic drug of a hexacoral origin. But the most serious problem for development of drugs from the sea remains supply. Two possible solutions, production by fermentation and by aquaculture, are described in the third part. Identification and culture of symbiotic bacteria which are responsible for the production of bioactive sponge metabolites are the main objectives for many researchers.

Sex, Drugs, and Sea Slime
Sex, Drugs, and Sea Slime

Author: Ellen Prager

Publisher: University of Chicago Press

Published: 2011-10

Total Pages: 214

ISBN-13: 0226678725

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When viewed from a quiet beach, the ocean can seem calm, even serene. But hidden beneath the sea's waves are a staggering variety of active creatures, engaged in the never-ending struggles of life--to reproduce, to eat, and to avoid being eaten. Marine scientist Ellen Prager takes us deep into the sea to introduce a cast of fascinating and bizarre creatures. From the tiny arrow worms whose voracious ways may lead to death by overeating, to the lobsters that battle rivals or seduce mates with their urine, Prager reveals the ways they interact as predators, prey, or potential mates. And while these animals make for some jaw-dropping stories--there's far more to Prager's account than entertaining anecdotes: again and again, she illustrates the crucial connections between life in the ocean and humankind, in everything from our food supply to our economy, and in drug discovery, biomedical research, and popular culture.--From publisher description.

Handbook of Anticancer Drugs from Marine Origin
Handbook of Anticancer Drugs from Marine Origin

Author: Se-Kwon Kim

Publisher: Springer

Published: 2014-11-27

Total Pages: 801

ISBN-13: 3319071459

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This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Pharmaceuticals in Marine and Coastal Environments
Pharmaceuticals in Marine and Coastal Environments

Author: Juan Carlos Duran-Alvarez

Publisher: Elsevier

Published: 2021-06-23

Total Pages: 704

ISBN-13: 0081029721

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Pharmaceuticals in Marine and Coastal Environments: Occurrence, Effects, and Challenges in a Changing World is divided into three sections that address a) coastal areas as the main entrance of pharmaceuticals into the ocean, b) the occurrence and distribution of pharmaceuticals in the environmental compartments of the ocean media, and c) the effects that such pollutants may cause to the exposed marine organisms. With its comprehensive discussions, the book provides a wide depiction of the current state-of-the-art on these topics in an effort to open new sources of investigation and find suitable solutions. - Includes maps edited by the Water Information Network System of the International Hydrological Program (IHP-WINS) - Provides a compilation of information regarding the occurrence and distribution of pharmaceuticals in the marine environment which will help establish new and more efficient monitoring programs and new research lines - Depicts the most important results of environmental risk assessments that can be used as a first step for further toxicological studies

Marine Compounds and Cancer
Marine Compounds and Cancer

Author: Friedemann Honecker

Publisher: MDPI

Published: 2018-06-26

Total Pages: 119

ISBN-13: 3038427659

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This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs

Marine Niche: Applications in Pharmaceutical Sciences
Marine Niche: Applications in Pharmaceutical Sciences

Author: Neelam M Nathani

Publisher: Springer Nature

Published: 2020-11-09

Total Pages: 454

ISBN-13: 9811550174

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This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases. Biomolecules have potential impacts on a diverse range of fields, including medical and pharmaceutical science, industrial science, biotechnology, basic research, molecular science, environmental science and climate change, etc. To understand and effectively apply medicinally important biomolecules, multidisciplinary approaches are called for. The ocean remains a rich biological resource, and the vast untapped potential of novel molecules from marine bio-resources has caught the interest of more and more researchers. These novel biological compounds have never been found in terrestrial or other ecosystems, but only in this rich niche. Advances in sampling techniques and technologies, along with increased funding for research and nature conservation, have now encouraged scientists to look deeper in the waters. Aquaculture supports both tremendous seafood production and the bulk production of marine-derived drugs. Furthermore, molecular methods are now being extensively employed to explore the untapped marine microbial diversity. With the help of molecular and biotech tools, the ability of marine organisms to produce new biosynthetic drugs can be greatly enhanced. This book provides an extensive compilation of the latest information on marine resources and their undisputedly vital role in the treatment of diverse ailments.

Phylum Bryozoa
Phylum Bryozoa

Author: Thomas Schwaha

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2020-11-23

Total Pages: 458

ISBN-13: 3110586312

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With an account of over 6.000 recent and 15.000 fossil species, phylum Bryozoa represents a quite large and important phylum of colonial filter feeders. This volume of the series Handbook of Zoology contains new findings on phylogeny, morphology and evolution that have significantly improved our knowledge and understanding of this phylum. It is a comprehensive book that will be a standard for many specialists but also newcomers to the field of bryozoology.

Drugged
Drugged

Author: Richard J. Miller

Publisher: Oxford University Press, USA

Published: 2014

Total Pages: 375

ISBN-13: 0199957975

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Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.

Marine Medicine
Marine Medicine

Author: Eric Weiss

Publisher: The Mountaineers Books

Published: 2012-04-19

Total Pages: 324

ISBN-13: 1594856613

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CLICK HERE to download the sections on abdominal injury, dislocations, and animal stings from Marine Medicine * Advice for sailing, pleasure boating, fishing, and diving emergencies * More than 100 illustrations * Near-shore or out-at-sea first aid covered * As vital a piece of gear as your PFD and signal flares This edition features the latest information on marine first aid. It includes chapters on hazardous marine life, submersion injury and dive medicine, rescue and evacuation of the sick and injured, wound cleaning and closing, and much more.

Venoms to Drugs
Venoms to Drugs

Author: Glenn F. King

Publisher: Royal Society of Chemistry

Published: 2015-01-27

Total Pages: 338

ISBN-13: 1782624376

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The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.