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Author: National Science Foundation (U.S.). Division of Environmental Systems and Resources
Publisher:
Published: 1973
Total Pages: 116
ISBN-13:
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Author: National Science Foundation (U.S.). Division of Environmental Systems and Resources
Publisher:
Published: 1973
Total Pages: 116
ISBN-13:
DOWNLOAD EBOOKAuthor: Jonathan Sterne
Publisher: Stata Press
Published: 2009-03-18
Total Pages: 0
ISBN-13: 9781597180498
DOWNLOAD EBOOKThis collection provides detailed descriptions of both standard and advanced meta-analytic methods and their implementation in Stata. Readers will gain access to the statistical methods behind the rapid increase in the number of meta-analyses reported in the social science and medical literature. The book shows how to conduct and interpret meta-analyses as well as produce highly flexible graphical displays. Using meta-regression, it examines reasons for between-study variability in effect estimates. The book also employs advanced methods for the meta-analysis of diagnostic test accuracy studies, dose-response meta-analysis, meta-analysis with missing data, and multivariate meta-analysis.
Author: Deirdre A. Kelly
Publisher: John Wiley & Sons
Published: 2009-01-26
Total Pages: 640
ISBN-13: 9781444300543
DOWNLOAD EBOOK“An excellent up-to-date comprehensive and practical text book dealing with all aspects of paediatric hepatobiliary disease. It will be useful to both generalists and specialists as it is clinically focused with a problem-solving approach and should be useful for day-to-day as well as more esoteric clinical problems. I found it useful in my general paediatric practice and my trainees have also found it useful. It is very practical with a diagnostic approach and lots of tables and clinical pathways to follow when confronted with day-to-day clinical problems. I have road-tested it in real life with good effect.” - Judging Panel, 2004 BMA Medical Book Competition Diseases of the Liver and Biliary System in Children, Third Edition provides a practical approach to the diagnosis and management of paediatric liver diseases, highlighting the importance of multidisciplinary team working and holistic management of the child and family. This fully revised edition has also been updated to cover recent advances in paediatric hepatology. It includes new chapters describing the effects of liver disease in pregnancy on mother and child through to adolescence. With increasing numbers of young people surviving into adult life this edition addresses the importance of managing adolescent transition effectively. Trainees, practising paediatric gastroenterologists and hepatologists will welcome the practical approach outlined in this text, while other healthcare professionals involved in the management of liver disease in children will find it an accessible and comprehensive reference.
Author: Trygve Tollefsbol
Publisher: Academic Press
Published: 2012-07-26
Total Pages: 617
ISBN-13: 0123884160
DOWNLOAD EBOOKEpigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs
Author: William Small, Jr.
Publisher: John Wiley & Sons
Published: 2017-04-17
Total Pages: 940
ISBN-13: 0470905522
DOWNLOAD EBOOKThis fully updated and enhanced third edition offers a highly practical, application-based review of the biological basis of radiation oncology and the clinical efficacy of radiation therapy. Revised edition of the classic reference in radiation oncology from Dr. C.C. Wang, whose practical approach to clinical application was legendary Includes the latest developments in the field: intensity modulated radiation therapy (IMRT), image guided radiation therapy, and particle beam therapy Includes two brand new chapters Palliative Radiotherapy, and Statistics in Radiation Oncology Features a vibrant and extremely comprehensive head and neck section Provides immediately applicable treatment algorithms for each tumor
Author: J. Whicher
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 316
ISBN-13: 9401129967
DOWNLOAD EBOOKOur understanding of inflammation has increased rapidly in recent years, due in large part to the impact of molecular biology and gene identification and cloning. This book brings together ideas from a number of different biochemical disciplines which are frequently not integrated. The first chapter gives a visual overview of the subject; the remaining chapters are organized into three themes: the affector molecules, the regulatory components and the processes of inflammation itself. This book is essential reading for the busy physician or pathologist who wants to be up-to-date with the latest developments in immunology as they affect the diagnosis and treatment of many conditions.
Author: John Redman Coxe
Publisher:
Published: 1808
Total Pages: 458
ISBN-13:
DOWNLOAD EBOOKAuthor: Betty R. Kirkwood
Publisher: John Wiley & Sons
Published: 2010-09-16
Total Pages: 512
ISBN-13: 1444392840
DOWNLOAD EBOOKBlackwell Publishing is delighted to announce that this book hasbeen Highly Commended in the 2004 BMA Medical Book Competition.Here is the judges' summary of this book: "This is a technical book on a technical subject but presentedin a delightful way. There are many books on statistics for doctorsbut there are few that are excellent and this is certainly one ofthem. Statistics is not an easy subject to teach or write about.The authors have succeeded in producing a book that is as good asit can get. For the keen student who does not want a book formathematicians, this is an excellent first book on medicalstatistics." Essential Medical Statistics is a classic amongst medicalstatisticians. An introductory textbook, it presents statisticswith a clarity and logic that demystifies the subject, whileproviding a comprehensive coverage of advanced as well as basicmethods. The second edition of Essential Medical Statistics hasbeen comprehensively revised and updated to include modernstatistical methods and modern approaches to statistical analysis,while retaining the approachable and non-mathematical style of thefirst edition. The book now includes full coverage of the mostcommonly used regression models, multiple linear regression,logistic regression, Poisson regression and Cox regression, as wellas a chapter on general issues in regression modelling. Inaddition, new chapters introduce more advanced topics such asmeta-analysis, likelihood, bootstrapping and robust standarderrors, and analysis of clustered data. Aimed at students of medical statistics, medical researchers,public health practitioners and practising clinicians usingstatistics in their daily work, the book is designed as both ateaching and a reference text. The format of the book is clear withhighlighted formulae and worked examples, so that all concepts arepresented in a simple, practical and easy-to-understand way. Thesecond edition enhances the emphasis on choice of appropriatemethods with new chapters on strategies for analysis and measuresof association and impact. Essential Medical Statistics is supported by a web siteat www.blackwellpublishing.com/essentialmedstats. Thisuseful online resource provides statistical datasets to download,as well as sample chapters and future updates.
Author: Stephen A. Zderic
Publisher: Springer Science & Business Media
Published: 2003-01-31
Total Pages: 334
ISBN-13: 9780306467592
DOWNLOAD EBOOKThis book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled "Pediatric Gender Assignment - A Critical Reappraisal". Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phenotype and imprinting of the central nervous system. Endocrinologists reviewed their experience in diagnosis and management, surgeons described traditional as well as innovative approaches, and there was strong representation from the ethical and behavioral sciences. In putting together such a panel, it was essential that we identify a cast of speakers who could address their viewpoints with strong convictions, and yet not let their passions render the meeting counter productive. We were not disappointed. While many differing points of view were firmly expressed by the panelists and audience, all viewpoints were accorded the respect they deserved. The concept behind the meeting and this book really originated in 1997 shortly after Diamond and Sigmundson published their long term follow up study of the John/Joan case.
Author: Michael Lübbert
Publisher: Springer Science & Business Media
Published: 2013-12-12
Total Pages: 332
ISBN-13: 3642384048
DOWNLOAD EBOOKThe growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically. This book first presents the latest evidence regarding the epigenetic regulation of hematopoietic stem cell differentiation and hemoglobin production. The significance of DNA methylation abnormalities in hematopoietic disorders and of epigenetic disturbances in lung cancer and other solid tumors is then discussed. A major part of the book, however, relates specifically to the translation of basic research and drug development to clinical applications, and in this context both present and future clinical strategies are considered. Individual chapters are devoted to the use of DNA hypomethylating agents and chromatin-modifying agents, and the treatment of hematologic malignancies and solid tumors by means of epigenetic agents is discussed in detail.