Difficult Diagnoses in Breast Pathology

Difficult Diagnoses in Breast Pathology

Author: Juan P. Palazzo

Publisher: Demos Medical Publishing

Published: 2011-06-22

Total Pages: 260

ISBN-13: 1933864796

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Breast cancer is the second leading cause of cancer death in women in the United States. For the pathologist, almost any breast lesion may produce diagnostic difficulty, especially due to frequently small samples (core biopsy specimens) and a variety of mimics and variants seen in specific types of lesions. Additionally, the difficulty of breast lesion diagnosis has risen dramatically in recent years due to the increased emphasis on stratifying patients for appropriate therapy on an individual basis; the wider range of both local and systemic therapeutic options, and the potential for earlier diagnosis through increased mammographic breast screening leading to a higher likelihood of a favorable outcome. Difficult Diagnoses in Breast Pathology will have a special focus on the most difficult diagnostic problems in breast disease for the surgical pathologist: needle core biopsy interpretation, diagnosis of precursor lesions and early stage disease, recognition of neoplastic mimics and other misleading variants, and other particularly difficult areas including appropriate use of newer immunohistochemical markers, where appropriate. Prognostic questions and early staging of special importance in the pathologist's collaboration with oncology clinicians and, increasingly, in informing patients and participating in ongoing management assessment. Throughout, the emphasis will be on a visual presentation with high-quality images on the more difficult problems and questions that the pathologist is likely to have in evaluation of breast disease.


Essentials of Diagnostic Breast Pathology

Essentials of Diagnostic Breast Pathology

Author: Farid Moinfar

Publisher: Springer Science & Business Media

Published: 2007-02-08

Total Pages: 483

ISBN-13: 354045117X

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Focuses on the essential information needed by pathologists in order to be able to interpret breast lesions (tumors) appropriately. This book talks about the diagnostic criteria with systematic analysis of differential diagnoses. It also demonstrates value and limitations of immunohistochemistry as a diagnostic adjunct.


Diagnostic Problems in Breast Pathology

Diagnostic Problems in Breast Pathology

Author: Frederick C. Koerner

Publisher: Elsevier Health Sciences

Published: 2009

Total Pages: 380

ISBN-13: 1416026126

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Introduction to the diagnosis of diseases of the breast Concepts basic to the analysis of epithelial proliferations Conventional ductal proliferations Apocrine proliferations Mucinous proliferations Lobular proliferations Concepts basic to the analysis of papillary proliferations Papilloma Papillary carcinoma Micropapillary proliferations Concepts basic to the diagnosis of sclerosing lesions Sclerosing adenosis Radial scar Low grade invasive ductal carcinoma Concepts basic to the analysis of fibroepithelial lesions Fibroadenoma Myxoid fibroadenoma Phyllodes tumor Hamartoma and fibroadenoma variant Pseudoangiomatous stromal hyperplasia.


Breast Pathology E-Book

Breast Pathology E-Book

Author: Frances P. O'Malley

Publisher: Elsevier Health Sciences

Published: 2011-08-01

Total Pages: 396

ISBN-13: 1455733393

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Breast Pathology, a title in the Foundations in Diagnostic Pathology series, provides all of the most essential information on the pathological entities encountered in practice in an easy-to-use format. Drs. Frances P. O'Malley, Sarah E. Pinder, and Anna Marie Mulligan provide unparalleled expert guidance for the study and diagnosis of a broad spectrum of breast lesions as well as the broad range of appearances of normal breast tissue. The consistent, practical format with a wealth of illustrations, at-a-glance boxes, and tables, make this title ideal for quick reference for both novices and experienced breast pathologists. Reference key information quickly and easily with a consistent, user-friendly format and at-a-glance boxes and tables throughout the text. Examine all aspects of a pathologic entity, including clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnosis, and prognostic and therapeutic considerations. Catch all the nuances of how pathological lesions present through over 400 full-color illustrations. Practice with confidence and overcome your toughest challenges with advice from the top minds in breast pathology. Apply the latest molecular diagnostic techniques to recognize newly identified classifications in breast disease. Get more of the information you need from new and expanded chapters covering a broad range of diseases and topics including fine needle aspiration cytology and the physical handling of core biopsy specimens; handling and evaluation of sentinel lymph nodes; diseases of the male breast; and state-of-the-art coverage of molecular advances in malignant breast disease. Prepare for the future of breast pathology with a new chapter dedicated to gene profiling and stem cell diagnostic techniques.


Breast Pathology

Breast Pathology

Author: Paul Peter Rosen

Publisher: Lippincott Williams & Wilkins

Published: 2010

Total Pages: 246

ISBN-13: 160831670X

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Edited by two eminent authorities on breast pathology, this heavily illustrated text offers essential guidance on diagnostic evaluation of needle core biopsies. More than 1,100 full-color illustrations depict the entire spectrum of breast pathology seen in needle core biopsies.


Practical Breast Pathology

Practical Breast Pathology

Author: Yan Peng

Publisher: Springer

Published: 2019-07-18

Total Pages: 269

ISBN-13: 3030165183

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This comprehensive volume reviews current topics and controversies in diagnostic breast pathology, and addresses frequently encountered diagnostic problems using a question and answer format and case presentations. Emphasis is placed on the diagnostic approach as it relates to morphology, clinical and radiographic correlation, differential diagnosis, and ancillary testing including immunohistochemical and molecular analyses. Answers are provided and serve as a practical, evidence-based, and problem solving guide to diagnostic issues having significant impacts on clinical management. Common but diagnostically challenging entities such as papillary lesions and fibroepithelial lesions are discussed in detail, as well as special types of breast cancer including solid papillary carcinoma, lobular lesions and its variants. Uncommon breast lesions such as mesenchymal, lymphoid, and metastatic lesions are also covered. Chapters discuss genetic alterations and molecular abnormalities in breast cancer, and commonly encountered interpretation dilemmas on immunohistochemistry in breast cancer and metastatic cancer to the breast with a focus on prognostic and predictive tumor biomarkers.


Difficult Diagnoses in Breast Pathology

Difficult Diagnoses in Breast Pathology

Author: Juan P. Palazzo, MD

Publisher: Demos Medical Publishing

Published: 2011-06-22

Total Pages: 259

ISBN-13: 1935281305

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Breast cancer is the second leading cause of cancer death in women in the United States. For the pathologist, almost any breast lesion may produce diagnostic difficulty, especially due to frequently small samples (core biopsy specimens) and a variety of mimics and variants seen in specific types of lesions. Additionally, the difficulty of breast lesion diagnosis has risen dramatically in recent years due to the increased emphasis on stratifying patients for appropriate therapy on an individual basis; the wider range of both local and systemic therapeutic options, and the potential for earlier diagnosis through increased mammographic breast screening leading to a higher likelihood of a favorable outcome. Difficult Diagnoses in Breast Pathology provides a highly visual presentation of the major problems and questions that a pathologist is likely to encounter in the evaluation of common and uncommon breast diseases. Coverage includes needle core biopsy interpretation, diagnosis of precursor lesions, early stage disease, and recognition of neoplastic mimics and other misleading variants. In addition, this book emphasizes particularly difficult areas including the use of newer immunohistochemical markers. Throughout, the emphasis is on an easily accessible presentation with tables and lists of key points summarizing major findings and numerous high-quality images supporting the text. Difficult Diagnoses in Breast Pathology will be a valuable reference for every pathologist who deals with the diagnosis of breast diseases. Difficult Diagnoses in Breast Pathology Features: Each chapter authored by recognized expert in the area Hundreds of high-quality images Tables and key points in each chapter summarize the most important findings Coverage based on addressing in detail the real-world diagnostic problems the pathologist will face in daily practice


Practical Surgical Pathology of the Breast

Practical Surgical Pathology of the Breast

Author: Juan P. Palazzo, MD

Publisher: Springer Publishing Company

Published: 2018-03-28

Total Pages: 418

ISBN-13: 1617052833

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Practical Surgical Pathology of the Breast is a comprehensive and accessible guide for the practicing pathologist and trainee. It provides anatomic pathologists with the essential knowledge and tools to navigate breast cases and classification systems that are commonly and uncommonly found in everyday practice. Particularly challenging topics such as understanding the molecular mechanisms linked to breast cancer and the interpretation of molecular tests, are covered in clear prose, along with useful discussions on diagnostic challenges written by world experts. The use of immunohistochemistry in breast pathology is discussed in detail and how to apply it to resolve diagnostic problems. As a result, the book simplifies difficult-to-master issues such as recognizing therapy-induced changes to breast specimens and identifying borderline breast lesions and many more. Each chapter features high-quality images and stains, tables that emphasize differential diagnoses, text that highlight common diagnostic pitfalls with corresponding tips, as well as helpful key points and how to reach an accurate diagnosis using appropriate procedures and tests. With Practical Surgical Pathology of the Breast as a guide, practitioners and residents can hone their diagnostic skills, resolve difficult cases and improve their approach to breast cases in their daily practice. Key Features: Written by world-renowned breast pathology experts Emphasizes the differential diagnosis problem-solving process found in everyday practice Contains over 700 high-quality images including numerous immunohistochemical stains which are essential when comparing breast entities Includes detailed coverage of core biopsy interpretation, precursors of mammary carcinoma and their mimics, papillary lesions, flat epithelial atypia, adenosis, microinvasive carcinoma, carcinomas with good prognosis, mesenchymal lesions, triple negative carcinomas, lymphomas of the breast, and interpretation of therapy-related changes Highlights diagnostic pitfalls and common problems that a pathologist will encounter and includes practical tips throughout to guide the proper interpretation of breast lesions and the proper application of tests to reach accurate diagnoses


Textbook of General Surgical Oncology

Textbook of General Surgical Oncology

Author: Shane Y. Morita

Publisher: McGraw Hill Professional

Published: 2017-12-01

Total Pages: 1887

ISBN-13: 0071793321

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A resource that combines oncologic principles with treatment plans for the surgical management of neoplasms Textbook of General Surgical Oncology is a practical and comprehensive reference that offers authoritative coverage of a wide variety of oncologic concepts and disorders. The book opens with detailed discussion of the general principles of molecular biology, cancer epidemiology, surgical oncology, radiation oncology, medical oncology, immunotherapy, nuclear imaging, and molecular diagnostics. The text then focuses on site-specific neoplasms, such as those of the skin, soft tissue, bone, head/neck, brain, lung, mediastinum, breast, pleura, peritoneum, as well as tumors that affect various systems, including the endocrine, gastrointestinal, hepatobiliary, genitourinary, gynecologic, and hematopoietic. · Each chapters is written by an internationally recognized expert on the topic · Learning aids include chapter-ending Q&A and Practical Pearls · Outstanding review for the new General Surgical Oncology certification examination


Improving Diagnosis in Health Care

Improving Diagnosis in Health Care

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2015-12-29

Total Pages: 473

ISBN-13: 0309377722

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Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.