Diagnostic Histochemistry
Diagnostic Histochemistry

Author: Mark R. Wick

Publisher: Cambridge University Press

Published: 2008-08-04

Total Pages: 472

ISBN-13: 9780521874106

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Pathology is an inherently subjective discipline, and therefore is often referred to as both an art and a science. Over the years, laboratory physicians have implemented special tissue stains and molecular techniques to limit subjectivity in the discipline. Beginning in the late 19th century, histochemical stains were developed to assess diagnostic biochemical reactions in tissue. Histochemistry has recently seen a resurgence in popularity because of the higher costs of other newer methods. Today, this technique is used by almost every pathology laboratory across the world. This book comprehensively covers all diseases for which that technique plays a central role in diagnosis. Every anatomic region is covered in detail with examples of appropriate staining techniques, and the book is heavily illustrated with over 850 color photomicrographs. This is the first monograph to be published on histochemistry in 15 years, and it is the only one that is diagnostically-oriented.

Immunohistochemistry: Basics and Methods
Immunohistochemistry: Basics and Methods

Author: Igor B. Buchwalow

Publisher: Springer Science & Business Media

Published: 2010-01-26

Total Pages: 153

ISBN-13: 3642046096

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This concise yet comprehensive guide to the methods and protocols of immunohistochemistry covers established techniques and current developments in the field such as the use of epitope tags, multiple immunolabeling and diagnostic immunohistochemistry.

Histological & Histochemical Methods
Histological & Histochemical Methods

Author: John Alan Kiernan

Publisher: Pergamon

Published: 1990

Total Pages: 454

ISBN-13:

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Revised and updated edition (1st was 1981) of a textbook on chemical and physical principles of fixation, staining and histochemistry. For students i all biological subjects using histological techniques, as well as researcher and medical laboratory technologists. Annotation copyright Book News, Inc

Diagnostic Pathology: Normal Histology - E-Book
Diagnostic Pathology: Normal Histology - E-Book

Author: Matthew R Lindberg

Publisher: Elsevier Health Sciences

Published: 2017-08-18

Total Pages: 500

ISBN-13: 0323548059

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Visually stunning and easy to use, this volume in the highly regarded Diagnostic Pathology series covers the normal histology of every organ system. This edition incorporates the most recent scientific and technological knowledge in the field to provide a comprehensive overview of all areas of normal histology, including introductory chapters on electron microscopy, immunofluorescence, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues. With nearly 1,800 outstanding images, this reference is an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. Unparalleled visual coverage with carefully annotated photomicrographs, spectacular gross images, electron micrographs, and medical illustrations Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Thoroughly updated content throughout, with all-new chapters on synovium and histologic artifacts, a thoroughly revised skeletal muscle chapter that now addresses normal histology in the setting of neuromuscular biopsy, and coverage of additional histologic variations that cause diagnostic confusion New content on immunohistochemistry; more image examples of newly recognized normal variations, mimics, and pitfalls; and expanded text in many sections for greater clarity and ease of reference

Diagnostic Pathology: Head and Neck E-Book
Diagnostic Pathology: Head and Neck E-Book

Author: Lester D. R. Thompson

Publisher: Elsevier Health Sciences

Published: 2016-04-20

Total Pages: 1193

ISBN-13: 0323428576

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Part of the highly regarded Diagnostic Pathology series, this updated volume is a visually stunning, easy-to-use reference covering all aspects of head and neck pathology. Outstanding images—including gross and microscopic pathology, a wide range of stains, and detailed medical illustrations—make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Highly templated text allows for quicky, easy reference. As always, Amirsys titles are image-rich. Thoroughly updated content throughout including new coverage of oropharyngeal carcinoma; HPV-associated, mammary analogue secretory carcinoma; EWSR1 driven tumors; molecular pathways as targets for salivary duct carcinoma; and much more High-quality, carefully annotated color images (50% new!) provide clinically and diagnostically important information on more than 315 new and evolving entities of the head and neck and endocrine organs State-of-the-art coverage of tumors, tumor development, and tumor genetics as well as normal histology, genetic testing, and new immunohistochemistry studies Fully integrated, searchable, and linked content between differential diagnostic categories is perfectly suited for residents, while updated genetic testing algorithms, new images, and outstanding graphics make this text ideal for both residents and practitioners Supporting studies are placed into clinical context, with tables and molecular flow charts that assist with management decisions and prognostic outcome predictions Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.

Handbook of Practical Immunohistochemistry
Handbook of Practical Immunohistochemistry

Author: Fan Lin

Publisher: Springer

Published: 2015-02-21

Total Pages: 756

ISBN-13: 1493915789

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In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Enzyme Histochemistry
Enzyme Histochemistry

Author: Z. Lojda

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 350

ISBN-13: 3642672345

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During recent years enzyme histochemical reactions have increasingly been considered as important, the reason being that enzyme histo chemistry is now a well-established link between morphology and bio chemistry. The development of numerous new methods and in particular the improvement of existing techniques contributed to the expansion of enzyme histochemical reactions. Today, the use of these methods allows detailed insight into molecular processes of single cells and their constituents. The selection of a suitable method for enzyme histochemical investigations needs thorough knowledge and critical evaluation of the reactions de scribed for the histochemical demonstration of enzymes and introduced in laboratory practice. Often, it is difficult for scientists primarily concerned with the application of methods and for laboratory assistants to comment on the value of an enzyme histochemical reaction. Our book will serve as a guide in this respect. It contains the most important histochemical methods for the localization of enzymes, all of which were checked by the authors themselves. These methods were often modified and frequently used for numerous different investigations of healthy and diseased organs in basic research and in routine practice.

Enzyme Histochemistry
Enzyme Histochemistry

Author: John D. Bancroft

Publisher: Oxford University Press, USA

Published: 1987

Total Pages: 84

ISBN-13:

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Enzyme histochemical methods depend on visual identification of reaction products for the identification and localization of specific enzymes within tissue. This concise handbook is designed to give students, pathology, MLSO's and research workers an outline and handy lab reference to the methods which have become routine in research and hospital histopathological laboratories. The author discusses the most reliable and diagnostically important methods, and offers suggestions for further reading.

Diagnostic Immunohistochemistry
Diagnostic Immunohistochemistry

Author: David J Dabbs

Publisher: Elsevier Health Sciences

Published: 2010-01-29

Total Pages: 3108

ISBN-13: 145570010X

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Diagnostic Immunohistochemistry presents the latest information and most reliable guidance on immunohistological diagnoses in surgical pathology. David J. Dabbs, MD and other leading experts bring you state-of-the-art coverage on genomic and theranostic applications, molecular anatomic pathology, immunocytology, Non-Hodgkin’s lymphoma, and more. Additional features such as tables discussing antibody specifications, differential diagnosis boxes, ancillary anatomic molecular diagnostics, and full-color histological images ensure user-friendly coverage that makes key information easy to find and apply. This concise and complete resource is today’s indispensable guide to the effective use of immunohistochemical diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Presents chapters arranged by organ system for comprehensive coverage of all relevant information in a convenient and intuitive organization. Provides quick reference graphs for antibodies throughout the text that illustrate the frequency of immunostaining for a variety of antibodies in tumors. Includes Key Diagnostic Points boxes in every chapter for a quick summary of text areas that are of particular importance. Features an expert author for each chapter to ensure coverage of the current state of the art. Provides guidance on the role of genomics in identifying genetic and molecular aspects of disease that may affect patient care and therapeutic approaches. Covers theranostic applications to enable you to evaluate therapeutic choices based on immunohistochemical results. Reflects the latest developments in the field through new chapters on molecular anatomic pathology and immunocytology, as well as updated chapters on immunohistology of the prostate, bladder, testis, and kidney and Non-Hodgkin’s lymphoma. Discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Presents key differential diagnoses boxes that provide tabular summaries of DDx and algorithms. Features discussions of ancillary anatomic molecular diagnostics as an adjunct to immunohistochemistry for a more well-rounded diagnostic approach.