The Diabetic Kidney
The Diabetic Kidney

Author: Pedro Cortes

Publisher: Springer Science & Business Media

Published: 2007-11-06

Total Pages: 553

ISBN-13: 1597451533

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A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Diabetic Nephropathy
Diabetic Nephropathy

Author: Joris J. Roelofs

Publisher: Springer

Published: 2018-10-29

Total Pages: 540

ISBN-13: 3319935216

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This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed. Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.

Podocytopathy
Podocytopathy

Author: Z.-H. Liui

Publisher: Karger Medical and Scientific Publishers

Published: 2014-05-16

Total Pages: 274

ISBN-13: 3318026514

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The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Diabetic Retinopathy and Cardiovascular Disease
Diabetic Retinopathy and Cardiovascular Disease

Author: C. Sabanayagam

Publisher: Karger Medical and Scientific Publishers

Published: 2019-06-03

Total Pages: 143

ISBN-13: 3318065072

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Diabetic retinopathy (DR), a common microvascular complication, has consistently been shown to be associated with an increased risk of cardiovascular disease (CVD). This book provides complete coverage of DR as a potential marker for CVD in those with diabetes. It succinctly reviews the epidemiological and pathogenic links of DR to various cardiovascular events including stroke, coronary artery disease, chronic kidney disease, heart failure, and mortality. Furthermore, it discusses the usefulness of DR in CVD risk prediction and cardiovascular safety of anti-VEGF therapy in diabetic patients. There are insights from contemporary diabetic trials that demonstrated the enhanced cardiovascular benefit of novel glucose lowering therapy. It also highlights the potential of novel retinal imaging to predict CVD and its risk factors using the state-of-the art artificial intelligence-based deep learning systems. This book will be an invaluable resource for specialists translating research findings into clinical care, including those in cardiology, endocrinology, ophthalmology, and general practitioners. IT will also be of interest to public health practitioners, researchers, graduate students, and biotech companies interested in developing retinal image-based diagnostic and prognostic tools.

The Kidney and Hypertension in Diabetes Mellitus
The Kidney and Hypertension in Diabetes Mellitus

Author: Carl Erik Mogensen

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 420

ISBN-13: 1475719744

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The first sporadic observations describing renal abnormalities in diabetes were published late in the 19th century, but systematic studies of the kidney in diabetes started only half a century ago after the paper by Cambier in 1934 and the much more famous study by Kimmelstiel and Wilson in 1936. These authors described two distinct features of renal involvement in diabetes: early hyperfiltration and late nephropathy. Diabetic nephropathy is, despite half a century of studies, still a very pertinent problem, renal disease in diabetes now being a very common cause of end-stage renal failure in Europe and North America and probably throughout the world. It is a very important part of the generalized vascular disease found in long-term diabetes as described by Knud Lundbaek in his mono graph Long-term Diabetes in 1953, published by Munks gaard, Copenhagen. Surprisingly, there has not been a comprehensive volume describing all aspects of renal involvement in diabetes, and the time is now ripe for such a volume summarizing the very considerable research activity within this field during the last decade and especially during the last few years. This book attempts to cover practically all aspects of renal involvement in diabetes. It is written by colleagues who are themselves active in the many fields of medical research covered in this volume: epidemiology, physiology and pathophysiology, laboratory methodology, and renal pathology. New studies deal with the dia gnosis and treatment of both incipient and overt nephropathy by metabolie, antihypertensive, and dietary invention.

Uric Acid in Chronic Kidney Disease
Uric Acid in Chronic Kidney Disease

Author: A. Treviño-Becerra

Publisher: Karger Medical and Scientific Publishers

Published: 2018-01-23

Total Pages: 161

ISBN-13: 3318062510

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Hyperuricemia is often associated with life-style related disorders such as diabetes mellitus, hypertension, and dyslipidemia, which, in turn, are major causes of CKD. Improved management of hyperuricemia is thus expected to be beneficial for both the general population and CKD patients. This book presents new information on uric acid in tubular transport, early recognition of renal lesions, genetic predisposition, preeclampsia, metabolic syndrome, diabetes, high blood pressure in the young, and the relationship with vitamin D. Moreover, the relationship between AKI and uric acid, as well as the rejection of renal transplants due to hyperuricemia, are discussed. This publication will be of interest to both general practitioners and researchers working in the field of CKD. It provides new insights into renal damage caused by hyperuricemia and into prevention and treatment possibilities.

Comprehensive Hypertension E-Book
Comprehensive Hypertension E-Book

Author: Gregory Y. H. Lip

Publisher: Elsevier Health Sciences

Published: 2007-06-28

Total Pages: 1247

ISBN-13: 0323070671

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Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Diabetic Nephropathy
Diabetic Nephropathy

Author: Luigi Gnudi

Publisher: Humana

Published: 2019-11-08

Total Pages: 0

ISBN-13: 9781493998401

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This book provides a toolkit of novel research approaches for investigators to study diabetic nephropathy, including critical experimental models from the fly to the fish, cells in culture, and in vivo mammalian approaches. The collection also explores powerful techniques to image the kidney, such as traditional histological techniques as well as electron, confocal, and two-photon microscopy, pathophysiology of the diabetic kidney, and gene editing and regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Nephropathy: Methods and Protocols seeks to foster new research directions and inspire ideas to enhance our understanding of diabetic nephropathy and to develop treatments for this condition.

The Epidemiology of Diabetes Mellitus
The Epidemiology of Diabetes Mellitus

Author: Jean Marie Ekoé

Publisher: John Wiley & Sons

Published: 2008-09-15

Total Pages: 720

ISBN-13: 0470779764

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The first edition of this book gained recognition as the definitive textbook of diabetes epidemiology. The second edition builds on this success, gathering recent information on international trends and data for diabetes mellitus. In particular, the book highlights the dramatic rise of Type 2 diabetes in children, adolescents and the elderly throughout the world. One new section features prevention and screening of both Type1 and Type 2 diabetes. Other new chapters cover the epidemiology of obesity and the impact of nutrition, and review available guidelines for better worldwide glycemic control. Future challenges, including the effects of antipsychotic treatment and HIV infection and therapy on diabetes, are also addressed. All chapters have been completely revised and updated, covering: definitions, classification and risk factors for diabetes new evidence for screening and prevention of Type 1 and Type 2 diabetes epidemiology of complications and associated risk factors economic aspects: the direct and indirect costs of diabetes. The Epidemiology of Diabetes Mellitus fills the need for a current compendium of diabetes epidemiology in the tradition of the first monumental text of the late Kelly West. It is essential reading for general practitioners, diabetologists, clinical endocrinologists, cardiologists, epidemiologists, nurses, dieticians, and other diabetes care providers, as well as health care decision makers.

Fundamentals of Renal Pathology
Fundamentals of Renal Pathology

Author: Agnes B. Fogo

Publisher: Springer Science & Business Media

Published: 2013-10-24

Total Pages: 223

ISBN-13: 3642390803

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Fundamentals of Renal Pathology is a compact and up-to-date resource on the basics of renal pathology that will be of particular value for residents and fellows in training in renal pathology, general pathology, and nephrology, but will also serve as a handy reference for the more experienced. This second, revised and updated edition of the book offers an integrated approach based on contributions from established experts in the field. Key diseases are discussed within the context of clinical presentations, with the emphasis on clinicopathological correlation and differential diagnosis. Topics discussed include glomerular diseases with nephrotic or nephritic syndrome presentations; systemic and vascular diseases affecting the kidney, including diseases affecting the renal transplant; tubulointerstitial diseases; and plasma cell dyscrasias and associated diseases. Well-chosen color illustrations and electron micrographs enhance and complement the text.