Cellular and Molecular Biology of Neuronal Development
Cellular and Molecular Biology of Neuronal Development

Author: Ira Black

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 376

ISBN-13: 1461327172

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A central problem in neurobiology concerns mechanisms that generate the pro found diversity and specificity of the nervous system. What is the substance of diversification and specificity at the molecular, cellular, and systems levels? 4 How, for example, do 1011 neurons each form approximately 10 interconnec tions, allowing normal physiological function? How does disruption of these processes result in human disease? These proceedings represent the efforts of molecular biologists, embryologists, neurobiologists, and clinicians to approach these issues. in this volume are grouped by subject to present the varieties The chapters of methods used to approach each individual area. Section I deals with embry ogenesis and morphogenesis of the nervous system. In Chapter 3, Weston and co-workers describe the use of monoclonal antibodies that recognize specific neuronal epitopes (including specific gangliosides) for the purpose of defining heterogeneity in the neural crest, an important model system. Immunocyto chemical analysis reveals the existence of distinct sUbpopulations within the crest at extremely early stages; cells express neuronal or glial binding patterns at the time of migration. Consequently, interactions with the environment may select for predetermined populations. Le Douarin reaches similar conclusions in Chapter 1 by analyzing migratory pathways and developmental potentials in crest of quail-

Developmental Neurobiology
Developmental Neurobiology

Author: Marcus Jacobson

Publisher:

Published: 1970

Total Pages: 496

ISBN-13:

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The book is presented as a timeline of development with emphasis on human and vertebrate biology. Fully documented examples exhaustively illustrate general principles in viewing development of structure and function as an integrated unity. All chapters have been extensively revised by noted international specialists. The book incorporates the most recent studies and research, including advances in stem cells and genomics. New chapters on aging and glial biology have been added. Continuity with previous editions is maintained by retention of the historical perspective for which this title is known. The book stresses the universal aspects of the development of the nervous system in both vertebrates and invertebrates, especially at the cellular level, but also compares and contrasts different levels of neuronal organization, giving much attention to phylogenetic and individual variations in neuronal ontogeny. With its comprehensive and completely updated coverage, generous illustrations, and a table of contents that reads like a Who's Who in neuroscience, this new and expanded Fourth Edition is a must book for the professional neurobiologist and others seeking definitive and authoritative information in this important field. Instructors, as well as graduate and advanced under-graduate students, will also appreciate its clearly presented information, historical references, and organization for classroom use.

Glial Cell Development
Glial Cell Development

Author: Kristjan R. Jessen

Publisher:

Published: 1996

Total Pages: 280

ISBN-13:

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Glial cell function and development has become a major focus of research in the neurosciences. Distinct glial progenitors have been identified, key glial genes have been cloned, and the growth factor regulation of glial survival, proliferation, and function is being unraveled. As a result, it will soon be possible to understand at the molecular level some vital functions, such as myelination and regulation of axon growth and repair. In this book, leading researchers review the current state of knowledge of all classes of glia and describe how this knowledge is being applied to the treatment of human disease. It is a valuable reference book for all researchers in developmental biology and neuroscience.

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published:

Total Pages: 1964

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.

The Neural Crest
The Neural Crest

Author: Nicole Le Douarin

Publisher: Cambridge University Press

Published: 1999-11-28

Total Pages: 494

ISBN-13: 9780521620109

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This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Enteric Glia
Enteric Glia

Author: Brian D. Gulbransen

Publisher: Biota Publishing

Published: 2014-07-01

Total Pages: 72

ISBN-13: 1615046615

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The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography