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Author: Hongbo Zhai
Publisher: CRC Press
Published: 2004-02-25
Total Pages: 1232
ISBN-13: 0203426274
DOWNLOAD EBOOKFor twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, De
Author: Klaus Peter Wilhelm
Publisher: CRC Press
Published: 2007-11-26
Total Pages: 1044
ISBN-13: 142000977X
DOWNLOAD EBOOKReflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated
Author: A. Wallace Hayes
Publisher: CRC Press
Published: 2014-10-10
Total Pages: 2186
ISBN-13: 1842145363
DOWNLOAD EBOOKHayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Author: Hongbo Zhai
Publisher: CRC Press
Published: 2004-02-25
Total Pages: 1232
ISBN-13: 9780415288620
DOWNLOAD EBOOKFor twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance. Updated and expanded to reflect the latest developments in skin toxicology, Dermatotoxicology, Sixth Edition includes fundamental information on the mechanisms of action of toxic substances on the skin, as well as practical information on the various methods to evaluating dermal toxicity. It is unparalleled in its coverage, and this new edition broadens its scope to include chapters on: * Barrier Creams * Cosmetic Reactions * UV Radiation Exposure * Electron Paramagnetic Resonance * Powdered Human Stratum Corneum * Iontophoresis * Permeability of Skin for Metal Compounds * Current Trends in Skin Cancer Research * Tape Stripping Method v. Stratum Corneum * Hazardous Substances from Soil and Water * Isolated Perfused Porcine Skin Flap * Physiologically-based Pharmacokinetic Models This completely revised and reworked edition constitutes a major contribution to the field of dermatotoxicology. Presenting the most modern concepts and methods in use today, researchers and clinicians will find this an invaluable resource time and time again.
Author: Francis N. Marzulli
Publisher: CRC Press
Published: 2019-05-07
Total Pages: 420
ISBN-13: 9781439805879
DOWNLOAD EBOOKThis work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
Author:
Publisher:
Published: 2004
Total Pages: 1576
ISBN-13:
DOWNLOAD EBOOKAuthor: Miranda A. Farage
Publisher: CRC Press
Published: 2016-04-19
Total Pages: 346
ISBN-13: 1420005316
DOWNLOAD EBOOKAddressing common misconceptions concerning the dermatologic composition and assessment of vulvular skin, this book is a unique compilation of current research and information on the anatomy, physiology, toxicology, microbiology, and diagnosis of the vulva and surrounding anatomical structures. A must-have source for anyone treating female patients, this source considers age and ethnicity factors and analyzes a wide range of symptoms, skin conditions, and diseases that physicians may encounter when caring for female patients.
Author: Francis Nicholas Marzulli
Publisher:
Published: 1983
Total Pages: 738
ISBN-13:
DOWNLOAD EBOOKThe most recent edition of the classic reference text contains 47 chapters on the mechanisms of toxicants on the skin, and related issues. The first part of the book provides background information and basic concepts of dermatotoxicology, and the second part covers methodologies employed to discern toxic effects. Some of the featured topics include: light induced dermal toxicity, problems associated with chronic occupational skin exposure to toxic chemicals, animal rights and animal research, and cosmetics safety. Annotation copyright by Book News, Inc., Portland, OR
Author: Byung-Mu Lee
Publisher: CRC Press
Published: 2012-09-21
Total Pages: 389
ISBN-13: 1841849545
DOWNLOAD EBOOKThis new edition of our bestselling book, Lu's Basic Toxicology, provides a number of key benefits that make it a must-read for toxicology specialists worldwide, including:Revision of a Bestseller - the new Sixth Edition provides the critical updates toxicologists need to keep up with the changing timesNew Information - on over-the-counter preparat
Author: Jim E. Riviere
Publisher: CRC Press
Published: 2005-08-24
Total Pages: 392
ISBN-13: 9780203020821
DOWNLOAD EBOOKMany experimental methods and mathematical modeling approaches rooted in disciplines outside of toxicology can be effectively applied to estimating dermal absorption. Dermal Absorption Models in Toxicology and Pharmacology explores current approaches and techniques that can be used to quantify dermal absorption with endpoints useful in both toxicology and pharmacology. The book begins with a review of basic principles and the in vitro and in vivo experimental approaches available for assessing dermal absorption of drugs and chemicals. This is followed by coverage of mathematical or in silico models for quantitating percutaneous absorption and the applications of these techniques to the risk assessment process. The remainder of the book explores scenarios where the unique properties of the chemicals being studied or the matrix in which they are exposed must be considered and then wraps up with a comparative analysis of chemical permeability in human and animal skin. Many of the books covering this subject are just too comprehensive and serve primarily as reference works. This book takes a different approach. Jim Riviere's editorial guidance ensures that the information is readable, accessible, authoritative, and concise, making it the perfect resource for familiarizing new researchers and students to the field and updating established scientists.
