Cutting Edge Therapies for Cancer in the 21st Century
Cutting Edge Therapies for Cancer in the 21st Century

Author: Pier Paolo Claudio

Publisher: Bentham Science Publishers

Published: 2014-04-23

Total Pages: 529

ISBN-13: 1608058808

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Cancer is a broad group of diseases involving unregulated cell growth with elevated death rates as more people live in old age with mass lifestyle changes occurring in the world. The causes of cancer are diverse, complex, and still only partially understood. The chances of surviving the disease vary remarkably by the type and location of the malignancy and the extent of disease at the start of treatment. Early cancer detection is proving to be a valid approach. Cancer can be detected in a number of ways, including the presence of certain signs and symptoms, screening tests, or medical imaging. Cancer therapy is dynamically changing and revision and change in patient management is constant as our knowledge increases. Cancer is routinely treated with chemotherapy, radiation therapy and surgery. Tailored cancer targeted therapy is becoming an emerging objective of today. In this book, a constructive group of cancer research experts bring the reader their shared vision, to give an extensive and realistic view of individual tumors such as breast, oral, prostate, gastric, and neuroendocrine tumors. New and contemporary terms and concepts in genetics and epigenetics, diet, anticancer treatments, and anticancer drug delivery systems are introduced in this volume. This reference highlights present experimental strategies and key findings that enhance our understanding of cancer and of future therapies. This eBook is aimed at a broad audience of undergraduates, medical students, PhDs, cancer researchers, and also cancer patient families with the goal to conceive a curiosity about the subjects presented that will hopefully lead to further studies.

Hepato-Pancreato-Biliary Malignancies
Hepato-Pancreato-Biliary Malignancies

Author: Cataldo Doria

Publisher: Springer

Published: 2022-09-27

Total Pages: 0

ISBN-13: 9783030416829

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Hepato-Pancreato-Biliary cancers are increasing in incidence, with pancreatic cancer now accounting for the third most cancer deaths in the United States. Typically these malignancies, as a group, are managed by the same key providers comprising a multidisciplinary team. This book is intended to provide a comprehensive review of the current knowledge in the field of hepato-pancreato-biliary malignancies, focusing on the practical and clinical care of patients. We take the approach of combining the collective expertise of an interventional gastroenterologist and a hepato-pancreato-biliary surgeon to provide the readers with accurate, succinct, and pragmatic information needed to formulate the most appropriate treatment plan for their patients with the aim of the best possible outcome. Managing patients with these cancers continues to be challenging because of continued dismal survival rates. Each section in this text is written by experts in their respective field, summarizing the most state-of-the-art, contemporary diagnostic and therapeutic tools available in the field. We believe this book will prove to be an invaluable, comprehensive resource for all members of the multidisciplinary team caring for patients with hepato-pancreato-biliary malignancies.

Antibody-Drug Conjugates
Antibody-Drug Conjugates

Author: Jeffrey Wang

Publisher: Springer

Published: 2015-03-05

Total Pages: 248

ISBN-13: 3319130811

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This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field.

Molecular Therapeutics
Molecular Therapeutics

Author: Pamela Greenwell

Publisher: John Wiley & Sons

Published: 2008-03-11

Total Pages: 264

ISBN-13: 9780470725146

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"This book should be useful to lecturers who teach senior undergraduates, graduate students, and students in the biomedical sciences in general. More globally, Greenwell and McCulley's book should encourage academicians of any stripe who for some time have been honing their lectures in a niche subject area to turn their courses into textbooks." –Biochemistry and Molecular Biology Education Molecular therapeutics refers to the developments in molecular biology that are focused on treating disease with new molecular-based drugs. By taking advantage of recent advances and increased understanding in the field of human genetics, this book provides essential background knowledge and key literature on a broad range of novel approaches and disciplines. These include making recombinant proteins, xenotransplantation gene therapy and therapeutic cloning. Molecular Therapeutics: 21st Century Medicine describes the techniques - including their associated benefits, problems, pitfalls - and discusses their applicability with respect to treating microbial, inherited, multifactoral and acquired diseases. The book also pays specific attention to the ethical issues associated with this new field. Cutting-edge topics and clinically relevant materials engage and maintain student interest Self-assessment questions are included throughout the book Features an additional web site, with a web forum, regular updates and PowerPoint slides of figures from the book Molecular Therapeutics: 21st Century Medicine is a comprehensive, accessible and engaging guide to the rapidly developing field of molecular therapeutics. It is essential reading for all students in this area of research and also of interest for health professionals involved in these novel therapies.

Withrow and MacEwen's Small Animal Clinical Oncology
Withrow and MacEwen's Small Animal Clinical Oncology

Author: Stephen J. Withrow

Publisher: Elsevier Health Sciences

Published: 2012-11-13

Total Pages: 775

ISBN-13: 1437723624

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With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology. "I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Reviewed by: Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK Date: July 2014 Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies. A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. Nearly 500 color images provide accurate depictions of specific diseases and procedures. Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology. Chemotherapy protocols are included when case studies prove clinical efficacy. Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases. NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development. NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts. NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.

A New Deal for Cancer
A New Deal for Cancer

Author: Abbe R. Gluck

Publisher: PublicAffairs

Published: 2021-11-16

Total Pages: 416

ISBN-13: 1541700627

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An unprecedented constellation of experts—leading cancer doctors, policymakers, cutting-edge researchers, national advocates, and more—explore the legacy and the shortcomings from the fifty-year war on cancer and look ahead to the future. The longest war in the modern era, longer than the Cold War, has been the war on cancer. Cancer is a complex, evasive enemy, and there was no quick victory in the fight against it. But the battle has been a monumental test of medical and scientific research and fundraising acumen, as well as a moral and ethical challenge to the entire system of medicine. In A New Deal for Cancer, some of today’s leading thinkers, activists, and medical visionaries describe the many successes in the long war and the ways in which our deeper failings as a society have held us back from a more complete success. Together they present an unrivaled and nearly complete map of the battlefield across dimensions of science, government, equity, business, the patient provider experience, and more, documenting our emerging understanding of cancer’s many unique dimensions and offering bold new plans to enable the American health care system to deliver progress and hope to all patients.

Cancer Cureology
Cancer Cureology

Author: Dr Steven a Vasilev

Publisher: Drbookpublishing.com

Published: 2017-02-09

Total Pages:

ISBN-13: 9781942065227

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Cancer Cureology, the ultimate survivor's holistic guide to integrative, natural, anti-cancer answers, is written by Dr. Steve Vasilev MD, America's first and leading quadruple board certified integrative gynecologic oncologist. Dr. Vasilev is also Clinical Professor at the David Geffen UCLA School of Medicine and the John Wayne Cancer Institute.

World Cancer Report 2008
World Cancer Report 2008

Author: International Agency for Research on Cancer

Publisher: International Agency for Research on Cancer

Published: 2008-12-31

Total Pages: 520

ISBN-13:

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"The World Cancer Report 2008" provides a comprehensive overview of cancer for all those working in the field of health-care and research, and the general reader as well. It presents information on cancer patterns, diagnosis, causes and prevention concisely, clearly outlining the growing public health crisis. Simultaneously, there is a clear message of hope: although cancer is a great and growing devastating disease, it is largely preventable.

Testicular Cancer: A Comprehensive Insight from Anatomy to Therapy
Testicular Cancer: A Comprehensive Insight from Anatomy to Therapy

Author: Dr. Spineanu Eugenia

Publisher: Dr. Spineanu Eugenia

Published:

Total Pages: 142

ISBN-13:

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This treatise offers an exhaustive exploration of testicular cancer, delving deep into its multifaceted dimensions. Beginning with a historical perspective, it traces the evolution of our understanding of the disease, highlighting the milestones in research and treatment. The work meticulously examines the anatomy of the testis, from its gross structure to the microscopic intricacies of cell types and structures, providing a foundational understanding crucial for medical professionals and researchers alike. The biochemical pathways of tumorigenesis are elucidated, shedding light on the complex interplay of genetics, environment, and endocrine disruptors. A detailed classification of tumor types, including rare variants, underscores the diversity of the disease and its myriad presentations. The treatise doesn't stop at the medical and scientific aspects; it ventures into the realm of holistic health, discussing integrative approaches, nutrition, mind-body practices, and natural therapies. Diagnostic modalities, from advanced imaging techniques to the latest in histopathological innovations, are thoroughly discussed. The work also delves into the cutting-edge treatments available, from surgical innovations to precision radiation techniques and chemotherapeutic agents. The aftermath of treatment, including organ-specific impacts, fertility concerns, and the broader cardiovascular, metabolic, and endocrine implications, are addressed with care and sensitivity. Prevention strategies, from testicular self-examinations to the role of lifestyle and environmental factors, are emphasized, advocating for proactive health measures. The treatise also touches upon the psychological, cultural, and ethical dimensions of testicular cancer, providing a well-rounded perspective. Concluding with a forward vision, it looks at the promising horizons of personalized medicine, stem cell research, and technological advancements in diagnostics and treatment. In essence, this treatise stands as a beacon of knowledge, bridging the gap between science, medicine, and patient care, and serving as an invaluable resource for anyone seeking a profound understanding of testicular cancer.