Cross-over Trials in Clinical Research
Cross-over Trials in Clinical Research

Author: Stephen S. Senn

Publisher: John Wiley & Sons

Published: 2003-07-25

Total Pages: 364

ISBN-13: 0470854588

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Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

Crossing Over
Crossing Over

Author: Stephen Jay Gould

Publisher: Three Rivers Press (CA)

Published: 2000

Total Pages: 174

ISBN-13:

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Crossing Over, the latest of three collaborations between scholar Stephen Jay Gould and artist Rosamond Wolff Purcell, brings together thought-provoking essays and uncannily beautiful photographs to disprove the popular notion that art and science exist in an antagonistic relationship. The essays and photographs collected here present art and science in conversation, rather than in opposition. As Gould writes in his preface, although the two disciplines may usually communicate in different dialects, when juxtaposed they strikingly reflect upon and enhance one another. Working together, Purcell's photographs and Gould's scientific musings speak to us about ourselves and our world in a hybrid language richer than either could command on its own. In an essay on individuality, for instance, Gould looks through the lens of evolutionary theory to address the controversial issue of cloning and the often misguided fears it evokes. As a society that exalts the concept of the individual, Gould argues, we sometimes fail to recognize that clones walk among us. Identical twins represent "the greatest of all challenges to our concept of individuality." Rosamond Purcell's photograph depicting the famous Siamese conjoined twins Eng and Chang conveys an eerie feeling that cannot be captured in words. Through its unique combination of words and photographs, Crossing Over prompts us to ponder not only the basis of the false dichotomy between art and science, but also the distinction of mind and nature, and of all humanly imposed categories of order. Gould and Purcell's work convinces the reader that a provocative interplay between art and science is not only possible, but inevitable and necessaryas well.

Design and Analysis of Cross-Over Trials, Second Edition
Design and Analysis of Cross-Over Trials, Second Edition

Author: Byron Jones

Publisher: CRC Press

Published: 2003-03-12

Total Pages: 390

ISBN-13: 1420036092

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The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.

Crossing the Quality Chasm
Crossing the Quality Chasm

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-07-19

Total Pages: 359

ISBN-13: 0309132967

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Second in a series of publications from the Institute of Medicine's Quality of Health Care in America project Today's health care providers have more research findings and more technology available to them than ever before. Yet recent reports have raised serious doubts about the quality of health care in America. Crossing the Quality Chasm makes an urgent call for fundamental change to close the quality gap. This book recommends a sweeping redesign of the American health care system and provides overarching principles for specific direction for policymakers, health care leaders, clinicians, regulators, purchasers, and others. In this comprehensive volume the committee offers: A set of performance expectations for the 21st century health care system. A set of 10 new rules to guide patient-clinician relationships. A suggested organizing framework to better align the incentives inherent in payment and accountability with improvements in quality. Key steps to promote evidence-based practice and strengthen clinical information systems. Analyzing health care organizations as complex systems, Crossing the Quality Chasm also documents the causes of the quality gap, identifies current practices that impede quality care, and explores how systems approaches can be used to implement change.

Model Rules of Professional Conduct
Model Rules of Professional Conduct

Author: American Bar Association. House of Delegates

Publisher: American Bar Association

Published: 2007

Total Pages: 216

ISBN-13: 9781590318737

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The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Networking the Nation
Networking the Nation

Author: Alison Chapman

Publisher:

Published: 2015

Total Pages: 352

ISBN-13: 0198723571

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How did nineteenth-century women's poetry shift from the poetess poetry of lyric effusion and hyper-femininity to the muscular epic of Elizabeth Barrett Browning's Aurora Leigh? Networking the Nation re-writes women's poetic traditions by demonstrating the debt that Barrett Browning's revolutionary poetics owed to a circle of American and British women poets living in Florence and campaigning in their poetry and in their salons for Italian Unification. These women poets--Isa Blagden, Elizabeth Kinney, Eliza Ogilvy, and Theodosia Garrow Trollope--formed with Barrett Browning a network of poetry, sociability, and politics, which was devoted to the mission of campaigning for Italy as an independent nation state. In their poetic experiments with the active lyric voice, in their forging of a transnational persona through the periodical press, in their salons and spiritualist seances, the women poets formed a network that attempted to assert and perform an independent unified Italy in their work. Networking the Nation maps the careers of these expatriate women poets who were based in Florence in the key years of Risorgimento politics, racing their transnational social and print communities, and the problematic but schismatic shift in their poetry from the conventional sphere of the poetess. In the fraught and thrilling engagement with their adopted nation's revolutionary turmoil, and in their experiments with different types of writing agency, the women poets in this book offer revolutions of other kinds: revolutions of women's poetry and the very act of writing.

Index Medicus
Index Medicus

Author:

Publisher:

Published: 2004

Total Pages: 1666

ISBN-13:

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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Turkish Immigrants in Western Europe and North America
Turkish Immigrants in Western Europe and North America

Author: Sebnem Koser Akcapar

Publisher: Routledge

Published: 2013-09-13

Total Pages: 223

ISBN-13: 1135754233

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Public and even scholarly debates usually focus on the integration problems of Muslim immigrants at the cost of overlooking the role of the growing number of migrant organizations in establishing a crucial link among immigrants themselves, as well as between them and their countries of origin and residence. This book aims to fill a gap in the vast literature on migration from Turkey by contributing the neglected aspect of civic and political participation of Turkish immigrants. It brings together a number of scholars who carried out extensive research on the associational culture of Turkish immigrants living in different countries in Europe and North America. In order to understand the diversity and dynamics within Turkish migrant communities living in these parts of the world yet maintaining transnational ties, this book offers a comparative and interdisciplinary approach to migrant organizations in general and civic participation and political mobilization of Turkish immigrants in particular. This book was published as a special issue in Turkish Studies.