Counter-Current Extraction: An Introduction to the Design and Operation of Counter-Current Extractors provide useful conclusions and results pertaining to counter-current extraction. This book aims to present illustrations of the various mathematical techniques as tools as well as means to an end. Organized into eight chapters, this book begins with an overview of the various aspects of the transfer of a single solute between two immiscible phases in counter-current flow. This text then describes all possible factors and obtains their relationship to the extraction factor and number of stages or transfer units. Other chapters consider the flows and concentrations in counter-current forward and back extraction. This book discusses as well the optimization of forward and back extraction using counter-current flow in differential and stagewise extractors. The final chapter deals with further applications of counter-current extractions. Undergraduates and researchers involved in the design and operation of counter-current extractors will find this book useful.
Recent Advances in Liquid-liquid Extraction focuses on the applications of liquid extraction. The selection first discusses solvent extraction. Concerns include organic and inorganic separations, mass transfer process, solvent extraction economics, and coalescence in liquid-liquid systems. The book focuses on the chemistry of solvent extraction. Extraction by acidic organophosphorus compounds; extraction by phosphorus-bonded oxygen-donor solvents; extraction by high-molecular weight amines; and synergistic extraction are elaborated. The book also focuses on industrial organic processes; industrial contacting equipment; response characteristics and control of extraction processes; and calculation of contactors with longitudinal mixing. The selection presents the study of longitudinal mixing in liquid-liquid contactors. Rotating disc contactors, packed columns, vibrating plate extractors, and Oldshue-Rushton columns are described. The text also discusses heat transfer by direct liquid-liquid contact and the coalescence of liquid droplets and liquid dispersion. The selection is a vital source of data for readers interested in liquid extraction.
This long awaited second edition of a popular textbook has a simple and direct approach to the diversity and complexity of food processing. It explains the principles of operations and illustrates them by individual processes. The new edition has been enlarged to include sections on freezing, drying, psychrometry, and a completely new section on mechanical refrigeration. All the units have been converted to SI measure. Each chapter contains unworked examples to help the student gain a grasp of the subject, and although primarily intended for the student food technologist or process engineer, this book will also be useful to technical workers in the food industry
In recent years the use of liquid—liquid extraction equipment has attracted widespread interest from all major chemical engineering, petroleum and pharmaceutical companies as well as university-based scientists and engineers. Liquid—Liquid Extraction Equipment presents : a critical analysis of all available information, including practical recommendations new ideas on performance enhancement and equipment selection an up-to-date review of research results on equipment performance illustrations of present understanding using well-known equipment a concise survey of past, present and forthcoming procedures The combination of the historical aspects of the subject, with extensive references and illustrations, make this a unique information source. All researchers, in industry and academia, using this type of equipment will find Liquid—Liquid Extraction Equipment an authoritative reference work and a solid basis for future research projects.
Countercurrent chromatography (CCC) is a separation technique in which the stationary phase is a liquid. The mobile phase is also a liquid, so biphasic liquid systems with at least two solvents are used. Centrifugal fields are used to hold the liquid stationary phase while pushing the liquid mobile phase through it. This comprehensive reference covers recent advancements in the two types of CCC machines: the high speed CCCs without rotary seals and with coiled spools and centrifugal partition chromatographs (CPC) with rotary seals and interconnected channels. Written by leading international experts in the CCC field, the book focuses on the liquid nature of the stationary phase: giving newcomers the basis to do CCC efficiently and rapidly; explaining the art of obtaining a biphasic liquid system; describing the flow patterns in both CPC and high speed CCC machines; showing possible other uses of a liquid stationary phase; presenting a wealth of applications in the separation of organic, pharmaceutical and inorganic mixtures; and demonstrating that even supercritical fluids can be used in CCC.
Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.
During the last ten years, several new extraction techniques have been developed that are faster, more automated and use less organic solvents compared to classical solvent extraction techniques. Furthermore, there is a clear trend going towards the use of (and research on) environmentally sustainable methods, which is encouraging for the future. Supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) are two of the most useful techniques for extraction of non-polar and medium polar solutes from solid and semi-solid samples. These techniques commonly use pressurized carbon dioxide or hot liquids such as water as extraction solvents, respectively. For aqueous samples, stir-bar sorptive extraction (SBSE) has recently been developed. These are some of the techniques that will be described in the proposed symposium series book. Focus will be on the extraction of various compounds from food and agricultural samples in either an analytical or a process-scale point-of-view. Several of the book chapters will compare the different techniques, and describe their advantages and disadvantages. Applications discussed in this book include SFE of biopolymers from distillers dried grains, SFE of lipids from oilseeds, PLE of functional ingredients from plants and herbs, tandem SFE/PLE of acrylamide from potato chips, SFE and PLE of cholesterol and fat from hamster liver, and steam distillation-extraction (SDE) and SBSE of flavors from shitake mushrooms.
The main challenge in modern solvent extraction separation is that most techniques are mainly empirical, specific and particular for narrow fields of practice and require a large degree of experimentation. This concise and modern book provides a complete overview of both solvent extraction separation techniques and the novel and unified competitive complexation/solvation theory. This novel and unified technique presented in the book provides a key for a preliminary quantitative prediction of suitable extraction systems without experimentation, thus saving researchers time and resources. Analyzes and compares both classical and new competitive models and techniques Offers a novel and unified competitive complexation / solvation theory that permits researchers to standardize some parameters, which decreases the need for experimentation at R&D Presents examples of applications in multiple disciplines such as chemical, biochemical, radiochemical, pharmaceutical and analytical separation Written by an outstanding scientist who is prolific in the field of separation science
