Distillation
Distillation

Author: Andrzej Gorak

Publisher: Academic Press

Published: 2014-07-22

Total Pages: 531

ISBN-13: 0123865484

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Distillation: Fundamentals and Principles — winner of the 2015 PROSE Award in Chemistry & Physics — is a single source of authoritative information on all aspects of the theory and practice of modern distillation, suitable for advanced students and professionals working in a laboratory, industrial plants, or a managerial capacity. It addresses the most important and current research on industrial distillation, including all steps in process design (feasibility study, modeling, and experimental validation), together with operation and control aspects. This volume features an extra focus on the conceptual design of distillation. - Winner of the 2015 PROSE Award in Chemistry & Physics from the Association of American Publishers - Practical information on the newest development written by recognized experts - Coverage of a huge range of laboratory and industrial distillation approaches - Extensive references for each chapter facilitates further study

Solvent Recovery Handbook
Solvent Recovery Handbook

Author: Ian McN. Smallwood

Publisher: CRC Press

Published: 2002

Total Pages: 440

ISBN-13: 9780849316029

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The pressure is on to cut plant emissions while still maintaining a cost-effective operation. Choosing the best solvent, being aware of potential problems, and the recovery of solvents has never been so important. Traditionally, solvents had been chosen on the basis of whether they can do the job effectively and economically. However, with regulations on exposure to solvent vapors becoming more stringent, selecting the solvent that meets regulatory, efficiency, and economical criteria as early as possible in the process has become paramount. Solvent Recovery Handbook, Second Edition sets out the physical properties of the fifty most commonly used solvents. The book supplies information on their behavior during and after use, health and fire hazards, the photochemical ozone creation potential (POCP), and recovery processes including practical aspects of the design and operation of batch stills. It delivers state-of-the art coverage of every available recovery and disposal technology - including removing solvents from gas, water, and residues, separating used solvents, and drying solvents. What's more, you'll find fact-filled sections on the latest equipment, safe effective operating procedures, choosing solvents with recovery in mind, and much more. Updated and expanded, Ian Smallwood's Solvent Recovery Handbook, Second Edition hands you all the practical tools you need to efficiently and cost-effectively process harmful organic solvents after re-capture.

Continuous Manufacturing of Pharmaceuticals
Continuous Manufacturing of Pharmaceuticals

Author: Peter Kleinebudde

Publisher: John Wiley & Sons

Published: 2017-09-05

Total Pages: 645

ISBN-13: 1119001323

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A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.

Distillation
Distillation

Author: Johann G. Stichlmair

Publisher: John Wiley & Sons

Published: 2021-05-19

Total Pages: 688

ISBN-13: 1119414687

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Distillation Principles and Practice Second Edition covers all the main aspects of distillation including the thermodynamics of vapor/liquid equilibrium, the principles of distillation, the synthesis of distillation processes, the design of the equipment, and the control of process operation. Most textbooks deal in detail with the principles and laws of distilling binary mixtures. When it comes to multi-component mixtures, they refer to computer software nowadays available. One of the special features of the second edition is a clear and easy understandable presentation of the principles and laws of ternary distillation. The right understanding of ternary distillation is the link to a better understanding of multi-component distillation. Ternary distillation is the basis for a conceptual process design, for separating azeotropic mixtures by using an entrainer, and for reactive distillation, which is a rapidly developing field of distillation. Another special feature of the book is the design of distillation equipment, i.e. tray columns and packed columns. In practice, empirical know-how is preferably used in many companies, often in form of empirical equations, which are not even dimensionally correct. The objective of the proposed book is the derivation of the relevant equations for column design based on first principles. The field of column design is permanently developing with respect to the type of equipment used and the know-how of two-phase flow and interfacial mass transfer.

The Management of Chemical Process Development in the Pharmaceutical Industry
The Management of Chemical Process Development in the Pharmaceutical Industry

Author: Derek Walker

Publisher: John Wiley & Sons

Published: 2008-03-03

Total Pages: 424

ISBN-13: 0470259507

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Here is a practical guide that not only presents insights into the organization and management of the disciplines involved in chemical process development but also provides basic knowledge of these disciplines, enabling process development practitioners to recognize and assimilate them in their work. This book illustrates practical considerations through many examples of the successful direction and integration of the activities of chemists, analysts, chemical engineers, and biologists, as well as safety, regulatory, and environmental professionals in productive teams. Moreover, this reference provides guidance on: Directing and carrying out specific tasks and courses of action Making and communicating clear and achievable decisions Solving problems on the spot Managing the administrative aspects of chemical process development The author, Dr. Derek Walker, has directed chemical process development work for four decades, combining firsthand chemical synthesis experience with many other disciplines needed to create chemical processes. You will benefit from his advice and unique insights into: Understanding the workings of matrix organizations Defining missions and creating action plans Developing interdisciplinary approaches to problem solving Holding review meetings, revising goals, and motivating staff Prioritizing programs and responses to emergencies In addition, you'll learn how successful chemists, in collaboration with other disciplines, define the best (green) chemistry for process scale-up, including accommodating FDA requirements in the last process steps and addressing safety and environmental matters early in their work. Case studies provide incisive perspective on these issues. A chapter on recognizing and patenting intellectual property emphasizes the importance of comprehensive literature surveys and understanding invention. A chapter on the future challenges you to think beyond narrow constraints and explore new horizons.

Membrane Technology and Applications
Membrane Technology and Applications

Author: Richard W. Baker

Publisher: John Wiley & Sons

Published: 2004-05-31

Total Pages: 556

ISBN-13: 9780470854457

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Table of Contents Preface Acknowledgments for the first edition Acknowledgments for the second edition 1 Overview of Membrane Science and Technology 1 2 Membrane Transport Theory 15 3 Membranes and Modules 89 4 Concentration Polarization 161 5 Reverse Osmosis 191 6 Ultrafiltration 237 7 Microfiltration 275 8 Gas Separation 301 9 Pervaporation 355 10 Ion Exchange Membrane Processes - Electrodialysis 393 11 Carrier Facilitated Transport 425 12 Medical Applications of Membranes 465 13 Other Membrane Processes 491 Appendix 523 Index 535.

The Reinforced Plastics Handbook
The Reinforced Plastics Handbook

Author: J. Murphy

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 596

ISBN-13: 1483292630

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The Handbook of Reinforced Plastics is a complete and practical manual for specifying and selecting reinforced plastic products and services. The handbook covers all materials and classes of equipment currently available, with over 550 pages of editorial, illustrations and tables.