Computing with Cells

Computing with Cells

Author: Pierluigi Frisco

Publisher: OUP Oxford

Published: 2009-05-21

Total Pages: 368

ISBN-13: 0191579637

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Membrane systems are a new class of distributed and parallel model of computation inspired by the subdivision of living cells into compartments delimited by membranes. Their hierarchical internal structure, their locality of interactions, their inherent parallelism and also their capacity to create new compartments, represent the distinguishing hallmarks of membrane systems. Membrane computing, the study of membrane systems, is a fascinating and fast growing area of research. The main streams of current investigations in Membrane Computing concern theoretical computer science and the modelling of complex systems. In this monograph Pierluigi Frisco considers the former trend: he presents an in-depth study of the formal language and computational complexity aspects of the most widely investigated models of membrane systems. This study gives a comprehensive understanding of the computational power of the models considered, shows different proof techniques used for such study, and introduces links highlighting the similarities and differences between the their computational power. These models cover a broad range of features, giving a grasp of the enormous flexibility of the framework offered by membrane systems. Aimed at graduates and researchers in the field, who can use it as a reference text, and to people with an initial interest in Membrane Computing, who can use it as a clear and up to date starting point for Membrane Computing.


A Computer Scientist's Guide to Cell Biology

A Computer Scientist's Guide to Cell Biology

Author: William W. Cohen

Publisher: Springer Science & Business Media

Published: 2007-07-23

Total Pages: 104

ISBN-13: 0387482784

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This book is designed specifically as a guide for Computer Scientists needing an introduction to Cell Biology. The text explores three different facets of biology: biological systems, experimental methods, and language and nomenclature. The author discusses what biologists are trying to determine from their experiments, how various experimental procedures are used and how they relate to accepted concepts in computer science, and the vocabulary necessary to read and understand current literature in biology. The book is an invaluable reference tool and an excellent starting point for a more comprehensive examination of cell biology.


Wetware

Wetware

Author: Dennis Bray

Publisher: Yale University Press

Published: 2009-05-26

Total Pages: 280

ISBN-13: 0300155441

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“A beautifully written journey into the mechanics of the world of the cell, and even beyond, exploring the analogy with computers in a surprising way” (Denis Noble, author of Dance to the Tune of Life). How does a single-cell creature, such as an amoeba, lead such a sophisticated life? How does it hunt living prey, respond to lights, sounds, and smells, and display complex sequences of movements without the benefit of a nervous system? This book offers a startling and original answer. In clear, jargon-free language, Dennis Bray taps the findings from the discipline of systems biology to show that the internal chemistry of living cells is a form of computation. Cells are built out of molecular circuits that perform logical operations, as electronic devices do, but with unique properties. Bray argues that the computational juice of cells provides the basis for all distinctive properties of living systems: it allows organisms to embody in their internal structure an image of the world, and this accounts for their adaptability, responsiveness, and intelligence. In Wetware, Bray offers imaginative, wide-ranging, and perceptive critiques of robotics and complexity theory, as well as many entertaining and telling anecdotes. For the general reader, the practicing scientist, and all others with an interest in the nature of life, this book is an exciting portal to some of biology’s latest discoveries and ideas. “Drawing on the similarities between Pac-Man and an amoeba and efforts to model the human brain, this absorbing read shows that biologists and engineers have a lot to learn from working together.” —Discover magazine “Wetware will get the reader thinking.” —Science magazine


Computing with Cells and Atoms

Computing with Cells and Atoms

Author: Cris Calude

Publisher: CRC Press

Published: 2000-10-26

Total Pages: 324

ISBN-13: 9780748408993

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At the turning of the millennium, a switch in computing technology is forecasted and looked for. Two main directions of research, both based on quite unconventional ideas are most promising - quantum computing and molecular computing. In the last few years, both of these methods have been intensely investigated. The present book is the first "friendly" presentation of basic ideas in these exciting areas. The style is rigorous, but without entering into excessive technicalities. Equal attention is paid to the main practical results reported so far and the main theoretical developments. The book is written for the educated layman and is self-contained, including all the necessary facts from mathematics, computer science, biology and quantum mechanics.


Computation in Living Cells

Computation in Living Cells

Author: Andrzej Ehrenfeucht

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 202

ISBN-13: 3662063719

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This is the first monograph on computation in living cells - one of the central and fastest growing areas of research in this field. Gene assembly in ciliates (unicellular organisms) is a splendid example of such computations. This work has helped to clarify important biological aspects of gene assembly, yielded novel insights into the nature of computation, and broadened our understanding of what computation is about. The monograph gives an accessible account of both the biology and the formal analysis of the gene assembly process. It can be used as a textbook for either graduate courses or seminars.


Computation in Cells and Tissues

Computation in Cells and Tissues

Author: R. Paton

Publisher: Springer Science & Business Media

Published: 2013-03-14

Total Pages: 349

ISBN-13: 3662063697

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The field of biologically inspired computation has coexisted with mainstream computing since the 1930s, and the pioneers in this area include Warren McCulloch, Walter Pitts, Robert Rosen, Otto Schmitt, Alan Turing, John von Neumann and Norbert Wiener. Ideas arising out of studies of biology have permeated algorithmics, automata theory, artificial intelligence, graphics, information systems and software design. Within this context, the biomolecular, cellular and tissue levels of biological organisation have had a considerable inspirational impact on the development of computational ideas. Such innovations include neural computing, systolic arrays, genetic and immune algorithms, cellular automata, artificial tissues, DNA computing and protein memories. With the rapid growth in biological knowledge there remains a vast source of ideas yet to be tapped. This includes developments associated with biomolecular, genomic, enzymic, metabolic, signalling and developmental systems and the various impacts on distributed, adaptive, hybrid and emergent computation. This multidisciplinary book brings together a collection of chapters by biologists, computer scientists, engineers and mathematicians who were drawn together to examine the ways in which the interdisciplinary displacement of concepts and ideas could develop new insights into emerging computing paradigms. Funded by the UK Engineering and Physical Sciences Research Council (EPSRC), the CytoCom Network formally met on five occasions to examine and discuss common issues in biology and computing that could be exploited to develop emerging models of computation.


Biocomputing

Biocomputing

Author: Panos M. Pardalos

Publisher: Springer Science & Business Media

Published: 2013-12-01

Total Pages: 265

ISBN-13: 1461302595

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In the quest to understand and model the healthy or sick human body, re searchers and medical doctors are utilizing more and more quantitative tools and techniques. This trend is pushing the envelope of a new field we call Biomedical Computing, as an exciting frontier among signal processing, pattern recognition, optimization, nonlinear dynamics, computer science and biology, chemistry and medicine. A conference on Biocomputing was held during February 25-27, 2001 at the University of Florida. The conference was sponsored by the Center for Applied Optimization, the Computational Neuroengineering Center, the Biomedical En gineering Program (through a Whitaker Foundation grant), the Brain Institute, the School of Engineering, and the University of Florida Research & Graduate Programs. The conference provided a forum for researchers to discuss and present new directions in Biocomputing. The well-attended three days event was highlighted by the presence of top researchers in the field who presented their work in Biocomputing. This volume contains a selective collection of ref ereed papers based on talks presented at this conference. You will find seminal contributions in genomics, global optimization, computational neuroscience, FMRI, brain dynamics, epileptic seizure prediction and cancer diagnostics. We would like to take the opportunity to thank the sponsors, the authors of the papers, the anonymous referees, and Kluwer Academic Publishers for making the conference successful and the publication of this volume possible. Panos M. Pardalos and Jose C.


Collision-Based Computing

Collision-Based Computing

Author: Andrew Adamatzky

Publisher: Springer Science & Business Media

Published: 2002-05-13

Total Pages: 588

ISBN-13: 9781852335403

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Collision-Based Computing presents a unique overview of computation with mobile self-localized patterns in non-linear media, including computation in optical media, mathematical models of massively parallel computers, and molecular systems. It covers such diverse subjects as conservative computation in billiard ball models and its cellular-automaton analogues, implementation of computing devices in lattice gases, Conway's Game of Life and discrete excitable media, theory of particle machines, computation with solitons, logic of ballistic computing, phenomenology of computation, and self-replicating universal computers. Collision-Based Computing will be of interest to researchers working on relevant topics in Computing Science, Mathematical Physics and Engineering. It will also be useful background reading for postgraduate courses such as Optical Computing, Nature-Inspired Computing, Artificial Intelligence, Smart Engineering Systems, Complex and Adaptive Systems, Parallel Computation, Applied Mathematics and Computational Physics.


Game of Life Cellular Automata

Game of Life Cellular Automata

Author: Andrew Adamatzky

Publisher: Springer Science & Business Media

Published: 2010-06-14

Total Pages: 576

ISBN-13: 1849962170

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In the late 1960s British mathematician John Conway invented a virtual mathematical machine that operates on a two-dimensional array of square cell. Each cell takes two states, live and dead. The cells’ states are updated simultaneously and in discrete time. A dead cell comes to life if it has exactly three live neighbours. A live cell remains alive if two or three of its neighbours are alive, otherwise the cell dies. Conway’s Game of Life became the most programmed solitary game and the most known cellular automaton. The book brings together results of forty years of study into computational, mathematical, physical and engineering aspects of The Game of Life cellular automata. Selected topics include phenomenology and statistical behaviour; space-time dynamics on Penrose tilling and hyperbolic spaces; generation of music; algebraic properties; modelling of financial markets; semi-quantum extensions; predicting emergence; dual-graph based analysis; fuzzy, limit behaviour and threshold scaling; evolving cell-state transition rules; localization dynamics in quasi-chemical analogues of GoL; self-organisation towards criticality; asynochrous implementations. The volume is unique because it gives a comprehensive presentation of the theoretical and experimental foundations, cutting-edge computation techniques and mathematical analysis of the fabulously complex, self-organized and emergent phenomena defined by incredibly simple rules.


The Digital Cell

The Digital Cell

Author: Stephen J. Royle

Publisher:

Published: 2019

Total Pages: 200

ISBN-13: 9781621822783

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"Cell biology is becoming an increasingly quantitative field, as technical advances mean researchers now routinely capture vast amounts of data. This handbook is an essential guide to the computational approaches, image processing and analysis techniques, and basic programming skills that are now part of the skill set of anyone working in the field"--