Computational Retinal Image Analysis

Computational Retinal Image Analysis

Author: Emanuele Trucco

Publisher: Academic Press

Published: 2019-11-19

Total Pages: 506

ISBN-13: 0081028172

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Computational Retinal Image Analysis: Tools, Applications and Perspectives gives an overview of contemporary retinal image analysis (RIA) in the context of healthcare informatics and artificial intelligence. Specifically, it provides a history of the field, the clinical motivation for RIA, technical foundations (image acquisition modalities, instruments), computational techniques for essential operations, lesion detection (e.g. optic disc in glaucoma, microaneurysms in diabetes) and validation, as well as insights into current investigations drawing from artificial intelligence and big data. This comprehensive reference is ideal for researchers and graduate students in retinal image analysis, computational ophthalmology, artificial intelligence, biomedical engineering, health informatics, and more. Provides a unique, well-structured and integrated overview of retinal image analysis Gives insights into future areas, such as large-scale screening programs, precision medicine, and computer-assisted eye care Includes plans and aspirations of companies and professional bodies


Computational Analysis of the Human Eye with Applications

Computational Analysis of the Human Eye with Applications

Author: Sumeet Dua

Publisher: World Scientific

Published: 2011

Total Pages: 467

ISBN-13: 9814340294

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Advances in semi-automated high-throughput image data collection routines, coupled with a decline in storage costs and an increase in high-performance computing solutions have led to an exponential surge in data collected by biomedical scientists and medical practitioners. Interpreting this raw data is a challenging task, and nowhere is this more evident than in the field of opthalmology. The sheer speed at which data on cataracts, diabetic retinopathy, glaucoma and other eye disorders are collected, makes it impossible for the human observer to directly monitor subtle, yet critical details. This book is a novel and well-timed endeavor to present, in an amalgamated format, computational image modeling methods as applied to various extrinsic scientific problems in ophthalmology. It is self-contained and presents a highly comprehensive array of image modeling algorithms and methodologies relevant to ophthalmologic problems. The book is the first of its kind, bringing eye imaging and multi-dimensional hyperspectral imaging and data fusion of the human eye, into focus. The editors are at the top of their fields and bring a strong multidisciplinary synergy to this visionary volume. Their "inverted-pyramid" approach in presenting the content, and focus on core applications, will appeal to students and practitioners in the field.


Front-End Vision and Multi-Scale Image Analysis

Front-End Vision and Multi-Scale Image Analysis

Author: Bart M. Haar Romeny

Publisher: Springer Science & Business Media

Published: 2008-10-24

Total Pages: 470

ISBN-13: 140208840X

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Many approaches have been proposed to solve the problem of finding the optic flow field of an image sequence. Three major classes of optic flow computation techniques can discriminated (see for a good overview Beauchemin and Barron IBeauchemin19951): gradient based (or differential) methods; phase based (or frequency domain) methods; correlation based (or area) methods; feature point (or sparse data) tracking methods; In this chapter we compute the optic flow as a dense optic flow field with a multi scale differential method. The method, originally proposed by Florack and Nielsen [Florack1998a] is known as the Multiscale Optic Flow Constrain Equation (MOFCE). This is a scale space version of the well known computer vision implementation of the optic flow constraint equation, as originally proposed by Horn and Schunck [Horn1981]. This scale space variation, as usual, consists of the introduction of the aperture of the observation in the process. The application to stereo has been described by Maas et al. [Maas 1995a, Maas 1996a]. Of course, difficulties arise when structure emerges or disappears, such as with occlusion, cloud formation etc. Then knowledge is needed about the processes and objects involved. In this chapter we focus on the scale space approach to the local measurement of optic flow, as we may expect the visual front end to do. 17. 2 Motion detection with pairs of receptive fields As a biologically motivated start, we begin with discussing some neurophysiological findings in the visual system with respect to motion detection.


Computational Analysis Of The Human Eye With Applications

Computational Analysis Of The Human Eye With Applications

Author: Sumeet Dua

Publisher: World Scientific

Published: 2011-04-21

Total Pages: 467

ISBN-13: 9814462055

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Advances in semi-automated high-throughput image data collection routines, coupled with a decline in storage costs and an increase in high-performance computing solutions have led to an exponential surge in data collected by biomedical scientists and medical practitioners. Interpreting this raw data is a challenging task, and nowhere is this more evident than in the field of opthalmology. The sheer speed at which data on cataracts, diabetic retinopathy, glaucoma and other eye disorders are collected, makes it impossible for the human observer to directly monitor subtle, yet critical details.This book is a novel and well-timed endeavor to present, in an amalgamated format, computational image modeling methods as applied to various extrinsic scientific problems in ophthalmology. It is self-contained and presents a highly comprehensive array of image modeling algorithms and methodologies relevant to ophthalmologic problems. The book is the first of its kind, bringing eye imaging and multi-dimensional hyperspectral imaging and data fusion of the human eye, into focus.The editors are at the top of their fields and bring a strong multidisciplinary synergy to this visionary volume. Their “inverted-pyramid” approach in presenting the content, and focus on core applications, will appeal to students and practitioners in the field.


Retinal Computation

Retinal Computation

Author: Greg Schwartz

Publisher: Academic Press

Published: 2021-08-07

Total Pages: 342

ISBN-13: 0128231777

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Retinal Computation summarizes current progress in defining the computations performed by the retina, also including the synaptic and circuit mechanisms by which they are implemented. Each chapter focuses on a single retinal computation that includes the definition of the computation and its neuroethological purpose, along with the available information on its known and unknown neuronal mechanisms. All chapters contain end-of-chapter questions associated with a landmark paper, as well as programming exercises. This book is written for advanced graduate students, researchers and ophthalmologists interested in vision science or computational neuroscience of sensory systems. While the typical textbook's description of the retina is akin to a biological video camera, the real retina is actually the world's most complex image processing machine. As part of the central nervous system, the retina converts patterns of light at the input into a rich palette of representations at the output. The parallel streams of information in the optic nerve encode features like color, contrast, orientation of edges, and direction of motion. Image processing in the retina is undeniably complex, but as one of the most accessible parts of the central nervous system, the tools to study retinal circuits with unprecedented precision are up to the task. This book provides a practical guide and resource about the current state of the field of retinal computation. - Provides a practical guide on the field of retinal computation - Summarizes and clearly explains important topics such as luminance, contrast, spatial features, motion and other computations - Contains discussion questions, a landmark paper, and programming exercises within each chapter


Image Analysis and Modeling in Ophthalmology

Image Analysis and Modeling in Ophthalmology

Author: Eddie Y. K. Ng

Publisher: CRC Press

Published: 2014-02-11

Total Pages: 412

ISBN-13: 1466559306

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Digital fundus images can effectively diagnose glaucoma and diabetes retinopathy, while infrared imaging can show changes in the vascular tissues. Likening the eye to the conventional camera, Image Analysis and Modeling in Ophthalmology explores the application of advanced image processing in ocular imaging. This book considers how images can be used to effectively diagnose ophthalmologic problems. It introduces multi-modality image processing algorithms as a means for analyzing subtle changes in the eye. It details eye imaging, textural imaging, and modeling, and highlights specific imaging and modeling techniques. The book covers the detection of diabetes retinopathy, glaucoma, anterior segment eye abnormalities, instruments on detection of glaucoma, and development of human eye models using computational fluid dynamics and heat transfer principles to predict inner temperatures of the eye from its surface temperature. It presents an ultrasound biomicroscopy (UBM) system for anterior chamber angle imaging and proposes an automated anterior segment eye disease classification system that can be used for early disease diagnosis and treatment management. It focuses on the segmentation of the blood vessels in high-resolution retinal images and describes the integration of the image processing methodologies in a web-based framework aimed at retinal analysis. The authors introduce the A-Levelset algorithm, explore the ARGALI system to calculate the cup-to-disc ratio (CDR), and describe the Singapore Eye Vessel Assessment (SIVA) system, a holistic tool which brings together various technologies from image processing and artificial intelligence to construct vascular models from retinal images. The text furnishes the working principles of mechanical and optical instruments for the diagnosis and healthcare administration of glaucoma, reviews state-of-the-art CDR calculation detail, and discusses the existing methods and databases. Image Analysis and Modeling in Ophthalmology includes the latest research development in the field of eye modeling and the multi-modality image processing techniques in ocular imaging. It addresses the differences, performance measures, advantages and disadvantages of various approaches, and provides extensive reviews on related fields.


Computational Methods and Deep Learning for Ophthalmology

Computational Methods and Deep Learning for Ophthalmology

Author: D. Jude Hemanth

Publisher: Elsevier

Published: 2023-02-18

Total Pages: 252

ISBN-13: 0323954146

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Computational Methods and Deep Learning for Ophthalmology presents readers with the concepts and methods needed to design and use advanced computer-aided diagnosis systems for ophthalmologic abnormalities in the human eye. Chapters cover computational approaches for diagnosis and assessment of a variety of ophthalmologic abnormalities. Computational approaches include topics such as Deep Convolutional Neural Networks, Generative Adversarial Networks, Auto Encoders, Recurrent Neural Networks, and modified/hybrid Artificial Neural Networks. Ophthalmological abnormalities covered include Glaucoma, Diabetic Retinopathy, Macular Degeneration, Retinal Vein Occlusions, eye lesions, cataracts, and optical nerve disorders. This handbook provides biomedical engineers, computer scientists, and multidisciplinary researchers with a significant resource for addressing the increase in the prevalence of diseases such as Diabetic Retinopathy, Glaucoma, and Macular Degeneration. - Presents the latest computational methods for designing and using Decision-Support Systems for ophthalmologic disorders in the human eye - Conveys the role of a variety of computational methods and algorithms for efficient and effective diagnosis of ophthalmologic disorders, including Diabetic Retinopathy, Glaucoma, Macular Degeneration, Retinal Vein Occlusions, eye lesions, cataracts, and optical nerve disorders - Explains how to develop and apply a variety of computational diagnosis systems and technologies, including medical image processing algorithms, bioinspired optimization, Deep Learning, computational intelligence systems, fuzzy-based segmentation methods, transfer learning approaches, and hybrid Artificial Neural Networks


Computational Vision and Medical Image Processing V

Computational Vision and Medical Image Processing V

Author: Joao Tavares

Publisher: CRC Press

Published: 2015-10-14

Total Pages: 374

ISBN-13: 1315642794

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VipIMAGE 2015 contains invited lectures and full papers presented at VIPIMAGE 2015 - V ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing (Tenerife, Canary Islands, Spain, 19-21 October, 2015). International contributions from 19 countries provide a comprehensive coverage of the current state-of-the-art in the fields o


High Resolution Imaging in Microscopy and Ophthalmology

High Resolution Imaging in Microscopy and Ophthalmology

Author: Josef F. Bille

Publisher: Springer

Published: 2019-08-13

Total Pages: 411

ISBN-13: 3030166384

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This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.