Computational Electrophysiology
Computational Electrophysiology

Author: Shinji Doi

Publisher: Springer Science & Business Media

Published: 2010-03-10

Total Pages: 159

ISBN-13: 4431538623

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Biological systems inherently possess much ambiguity or uncertainty. Computational electrophysiology is the one area, from among the vast and rapidly growing discipline of computational and systems biology, in which computational or mathematical models have succeeded. This textbook provides a practical and quick guide to both computational electrophysiology and numerical bifurcation analysis. Bifurcation analysis is a very powerful tool for the analysis of such highly nonlinear biological systems. Bifurcation theory provides a way to analyze the effect of a parameter change on a system and to detect a critical parameter value when the qualitative nature of the system changes. Included in this work are many examples of numerical computations of bifurcation analysis of various models as well as mathematical models with different abstraction levels from neuroscience and electrophysiology. This volume will benefit graduate and undergraduate students as well as researchers in diverse fields of science.

Differential Equations for Studies in Computational Electrophysiology
Differential Equations for Studies in Computational Electrophysiology

Author: Karoline Horgmo Jæger

Publisher: Springer Nature

Published: 2023-05-27

Total Pages: 134

ISBN-13: 3031308522

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This open access text aims at giving you the simplest possible introduction to differential equations that are used in models of electrophysiology. It covers models at several spatial and temporal scales with associated numerical methods. The text demonstrates that a very limited number of fundamental techniques can be used to define numerical methods for equations ranging from ridiculously simple to extremely complex systems of partial differential equations. Every method is implemented in Matlab and the codes are freely available online. By using these codes, the reader becomes familiar with classical models of electrophysiology, like the cable equation, the monodomain model, and the bidomain model. But modern models that have just started to gain attention in the field of computational electrophysiology are also presented. If you just want to read one book, it should probably not be this one, but if you want a simple introduction to a complex field, it is worth considering the present text.

Computational Cardiology
Computational Cardiology

Author: Frank B. Sachse

Publisher: Springer

Published: 2005-01-12

Total Pages: 364

ISBN-13: 3540259260

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This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, E-Book
Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, E-Book

Author: Jose Jalife

Publisher: Elsevier Health Sciences

Published: 2021-12-16

Total Pages: 1709

ISBN-13: 0323757464

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Fully updated from cover to cover, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need—from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology. - Packs each chapter with the latest information necessary for optimal basic research as well as patient care. - Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. - Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation. - Includes 47 new chapters covering both basic science and clinical topics. - Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. - Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online. - Recipient of a 2018 Highly Commended award from the British Medical Association. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges
Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges

Author: Oscar Camara

Publisher: Springer

Published: 2016-01-08

Total Pages: 229

ISBN-13: 3319287125

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This book constitutes the thoroughly refereed post-workshop proceedings of the 6th International Workshop on Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges, STACOM 2015, held in conjunction with MICCAI 2015, in Munich, Germany, in October 2015. The 23 revised full workshop papers were carefully reviewed and selected from 34 submissions. The papers cover a wide range of topics such cardiac image processing, atlas construction, statistical modeling of cardiac function across different patient populations, cardiac mapping, cardiac computational physiology, model customization, image-based modelling and image-guided interventional procedures, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analysis.

Statistical Atlases and Computational Models of the Heart. M&Ms and EMIDEC Challenges
Statistical Atlases and Computational Models of the Heart. M&Ms and EMIDEC Challenges

Author: Esther Puyol Anton

Publisher: Springer Nature

Published: 2021-01-28

Total Pages: 427

ISBN-13: 3030681076

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This book constitutes the proceedings of the 11th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2020, as well as two challenges: M&Ms - The Multi-Centre, Multi-Vendor, Multi-Disease Segmentation Challenge, and EMIDEC - Automatic Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRI Challenge. The 43 full papers included in this volume were carefully reviewed and selected from 70 submissions. They deal with cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, artificial intelligence, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods.

Fluorine Metabolism, Transport and Enzymatic Chemistry
Fluorine Metabolism, Transport and Enzymatic Chemistry

Author:

Publisher: Elsevier

Published: 2024-04-23

Total Pages: 378

ISBN-13: 0443236445

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Fluorine Metabolism, Transport and Enzymatic Chemistry, Volume 696 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Fluorine Metabolism, Transport, and Enzymatic Chemistry. Chapters in this new release include Determination of fluoride sensitivity and resistance in oral biofilm models, NMR methods to detect fluoride binding and transport by membrane proteins, Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans, Measurement of fluoride efflux from lipid vesicles and cells, Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation, and more.Additional chapters cover Computational approaches to investigate F- binding, selectivity and transport in F- exporters, Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities, Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae, and Synthesis of fluorophenylalanine-encoded proteins in HEK cells. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology series - Updated release includes the latest information on Fluorine Metabolism, Transport, and Enzymatic Chemistry

Supercomputing
Supercomputing

Author: Vladimir Voevodin

Publisher: Springer Nature

Published: 2019-12-09

Total Pages: 757

ISBN-13: 3030365921

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This book constitutes the refereed post-conference proceedings of the 5th Russian Supercomputing Days, RuSCDays 2019, held in Moscow, Russia, in September 2019. The 60 revised full papers presented were carefully reviewed and selected from 127 submissions. The papers are organized in the following topical sections: parallel algorithms; supercomputer simulation; HPC, BigData, AI: architectures, technologies, tools; and distributed and cloud computing.