Comparison of the Siglec Family Members of the Immunoglobulin Superfamily
Author: Nicholas Paul Connolly
Publisher:
Published: 2002
Total Pages: 0
ISBN-13:
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Essentials of Glycobiology
Author: Ajit Varki
Publisher: CSHL Press
Published: 1999
Total Pages: 694
ISBN-13: 9780879696818
DOWNLOAD EBOOKSugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Lectin in Host Defense Against Microbial Infections
Author: Shie-Liang Hsieh
Publisher: Springer Nature
Published: 2020-03-09
Total Pages: 240
ISBN-13: 9811515808
DOWNLOAD EBOOKThis book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ‘pathogen-associated molecular patterns’ or ‘damage-associated molecular patterns’. As such, microbes’ interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions.
Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease
Author: Shyamasree Ghosh
Publisher: Academic Press
Published: 2020-01-08
Total Pages: 386
ISBN-13: 0128161272
DOWNLOAD EBOOKSialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. - Discusses the sialic acids and their role in different diseases (other than cancer) - Provides an understanding of sialylations as post translational modifications (PTM) - Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health - Gives insights on the importance of sialic acid biology through animal models
The Adhesion Molecule FactsBook
Author:
Publisher: Elsevier
Published: 2000-08-24
Total Pages: 325
ISBN-13: 0080525970
DOWNLOAD EBOOKThis updated and expanded Second Edition of The Adhesion Molecule FactsBook has nearly double the number of entries of the First Edition, and provides a compendium of the major cell surface adhesion molecules. The introductory chapters detail the organization of the data in the entries section, provide a background to the main adhesion molecule families, and inform the reader how to access information on adhesion molecules on the Internet. The entries have been designed to allow the reader to quickly establish the main structure and functional features of each molecule and where to find information. - Alternative nomenclature - Tissue distribution and regulation of expression - Ligands - Gene organization and chromosomal location - Protein structure and molecular weights - Amino acid sequence of the most commonly studied organisms - PIR, SWISSPROT, and EMBL/GenBank accession numbers - Biological function - Key references
Eosinophils in Health and Disease
Author: James J. Lee
Publisher: Academic Press
Published: 2012-11-02
Total Pages: 679
ISBN-13: 012394385X
DOWNLOAD EBOOKEosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.
Glycobiology of the Nervous System
Author: Robert K. Yu
Publisher: Springer
Published: 2014-08-23
Total Pages: 590
ISBN-13: 1493911546
DOWNLOAD EBOOKA thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
Biology of the Sialic Acids
Author: A. Rosenberg
Publisher: Springer Science & Business Media
Published: 1995-07-31
Total Pages: 398
ISBN-13: 9780306449741
DOWNLOAD EBOOKAbraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables.
Evolution of Atopic Dermatitis in the 21st Century
Author: Ichiro Katayama
Publisher: Springer
Published: 2017-12-06
Total Pages: 368
ISBN-13: 9811055416
DOWNLOAD EBOOKThis comprehensive guide offers a state-of-the-art overview of basic and clinical aspects of atopic dermatitis (AD). The name "atopic dermatitis" was first used in 1933, and Drs. Lewis Webb Hill and Marion B. Sulzberger presented their report "Evolution of atopic dermatitis" in 1935. Their observations accurately forecasted the contemporary issues in the management of the condition, such as the conclusions that should be drawn from our understanding of the pathogenesis of AD, and the use of steroids as the main treatment. Several aggravating factors have recently been identified, and these also need to be addressed. In this context, the expert contributors to this book describe and discuss the evolution of atopic dermatology from Sulzberger’s era to the present day, including clinical manifestations, etiopathology and treatment. In addition, it explores skin care intervention, the role of microbiom and GWAS studies, and presents unique, previously unpublished cohort studies. It provides insights into the dynamic changes in AD since Sulzberger introduced topical steroids for its treatment. It is a valuable resource for dermatologists, medical practitioners and researchers who are interested in atopic dermatology.
Textbook of Pediatric Gastroenterology, Hepatology and Nutrition
Author: Stefano Guandalini
Publisher: Springer
Published: 2015-09-30
Total Pages: 889
ISBN-13: 3319171690
DOWNLOAD EBOOKThis textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives. Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.
