Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Author: Agency for Health Care Research and Quality (U.S.)

Publisher: Government Printing Office

Published: 2013-02-21

Total Pages: 236

ISBN-13: 1587634236

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This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)


Improving Diagnosis in Health Care

Improving Diagnosis in Health Care

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2015-12-29

Total Pages: 473

ISBN-13: 0309377722

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Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.


Artificial Intelligence

Artificial Intelligence

Author: Lu Fang

Publisher: Springer Nature

Published: 2022-01-01

Total Pages: 815

ISBN-13: 3030930467

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This two-volume set LNCS 13069-13070 constitutes selected papers presented at the First CAAI International Conference on Artificial Intelligence, held in Hangzhou, China, in June 2021. Due to the COVID-19 pandemic the conference was partially held online. The 105 papers were thoroughly reviewed and selected from 307 qualified submissions. The papers are organized in topical sections on applications of AI; computer vision; data mining; explainability, understandability, and verifiability of AI; machine learning; natural language processing; robotics; and other AI related topics.


Computational Intelligence in Pattern Recognition

Computational Intelligence in Pattern Recognition

Author: Asit Kumar Das

Publisher: Springer Nature

Published: 2021-09-04

Total Pages: 756

ISBN-13: 9811625433

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This book features high-quality research papers presented at the 3rd International Conference on Computational Intelligence in Pattern Recognition (CIPR 2021), held at the Institute of Engineering and Management, Kolkata, West Bengal, India, on 24 – 25 April 2021. It includes practical development experiences in various areas of data analysis and pattern recognition, focusing on soft computing technologies, clustering and classification algorithms, rough set and fuzzy set theory, evolutionary computations, neural science and neural network systems, image processing, combinatorial pattern matching, social network analysis, audio and video data analysis, data mining in dynamic environments, bioinformatics, hybrid computing, big data analytics and deep learning. It also provides innovative solutions to the challenges in these areas and discusses recent developments.