Time-correlated single photon counting

Time-correlated single photon counting

Author: Desmond O'Connor

Publisher: Academic Press

Published: 2012-12-02

Total Pages: 299

ISBN-13: 0323141447

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Time-correlated Single Photon Counting has been written in the hope that by relating the authors' experiences with a variety of different single photon counting systems, they may provide a useful service to users and potential users of this formidably sensitive technique. Of all the techniques available to obtain information on the rates of depopulation of excited electronic singlet states of molecular species, monitoring of fluorescence provides, in principle, the simplest and most direct measure of concentration. This volume comprises eight chapters, with the first focusing on the time dependence and applications of fluorescence. Succeeding chapters go on to discuss basic principles of the single photon counting lifetime measurement; light sources; photomultipliers; electronics; data analysis; nanosecond time-resolved emission spectroscopy; time dependence of fluorescence anisotropy. This book will be of interest to practitioners in the field of chemistry.


Textbook of Hyperbaric Medicine

Textbook of Hyperbaric Medicine

Author: Kewal K. Jain

Publisher: Springer

Published: 2016-11-25

Total Pages: 660

ISBN-13: 3319471406

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This comprehensive volume captures the latest scientific evidence, technological advances, treatments and impact of biotechnology in hyperbaric oxygen therapy. Divided into three distinct sections, the book begins with basic aspects that include history, equipment, safety and diagnostic approaches; this is followed by clinical applications for hyperbaric oxygen therapy in various modalities; the last section provides an overview of hyperbaric medicine as a specialty with best practices from around the world. Integration of multidisciplinary approaches to complex disorders are also covered. Updated and significantly expanded from previous editions, Textbook of Hyperbaric Medicine, 6th Edition will continue to be the definitive guide to this burgeoning field for students, trainees, physicians and specialists.


Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

Author: James A. Dykens

Publisher: Wiley-Interscience

Published: 2008-09-22

Total Pages: 0

ISBN-13: 9780470111314

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This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process. It discusses mitochondrial impairment to organs, skeletal muscle, and nervous systems and details methodologies used to assess mitochondria function. It covers both in vitro and in vivo methods for analysis and includes the latest models. This is the authoritative reference on drug-induced mitochondrial dysfunction for safety assessment professionals in the pharmaceutical industry and for pharmacologists and toxicologists in both drug and environmental health sciences.


International Entrepreneurship in the Life Sciences

International Entrepreneurship in the Life Sciences

Author: Marian V. Jones

Publisher: Edward Elgar Publishing

Published: 2011-11-01

Total Pages: 361

ISBN-13: 1849808201

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'The processes of internationalization, innovation and venture-creation in high-technology new ventures are inextricably intertwined. This is particularly true in the uncertain and troubled waters of the life sciences industry where startups with very uncertain futures are required to face significant challenges in short windows of opportunity. Navigating these waters is not straightforward, either for those immediately involved in it, or for those trying to understand it. This book is a must-read for anyone who is serious about understanding entrepreneurship in the biotechnology industry.' Alberto Onetti, CrESIT (Research Center for Innovation and Life Science Management), Italy In this thought-provoking book, leading experts explore why international entrepreneurship is important to the life sciences industry. From multi-disciplinary and cross-national perspectives, they question why international entrepreneurship scholars might usefully invest interest in research focused on one specific industry context. The book addresses contemporary challenges of relevance to life science firms and draws on leading-edge debates in international entrepreneurship research. Topics include: the nature of the born-global firm; the development of international capabilities and competencies; the role of local and international partnerships and alliances; competitiveness, opportunity recognition and orientation; and the role of specialized complementary assets in internationalization. It concludes by proposing an agenda for future research across the underpinning fields of innovation, entrepreneurship and internationalization. This book will prove a stimulating read for academics, students and researchers with an interest in international business, management and entrepreneurship, as well as for practitioners in the health professions or life sciences academics who are, or may become, entrepreneurs.


Practical TPM

Practical TPM

Author: James Leflar

Publisher: CRC Press

Published: 2001-01-05

Total Pages: 388

ISBN-13: 9781563272424

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Agilent Technologies, formerly Hewlett-Packard's Test and Measurement Division, operates an integrated circuit fabrication plant in Fort Collins, Colorado. Guided by Masaji Taijiri, the author of 7 Steps to Autonomous Maintenance (see page 34), author Jim Leflar and his team at Agilent developed a complete TPM program for the complex equipment on their shop floor. Drawn from these experiences, Practical TPM is a must read for anyone who wants to begin successful TPM implementation. Part I explains the fundamental concepts of TPM, including the six basic principles of TPM, the goals of TPM, cultural changes resulting from TPM, and the keys to successful implementation. Part II — the heart of the book — describes, in step-by-step detail, the evolution of Agilent's TPM program. Each phase is clearly defined and demonstrated; the working tools and systems developed by the Agilent TPM team in the process are discussed at length. To conclude, Part III focuses on developing a vision and a strategy for your own successful TPM program. Replete with annotated photographs and illustrations documenting Agilent's successful program, Practical TPM: Successful Equipment Management at Agilent Technologies offers an invaluable roadmap to TPM implementation. The book covers: A step-by-step TPM program as implemented at a major US corporation The 5-why analysis method Examples of one-point lessons Using visual controls in a TPM program Tools for understanding equipment failures Improving machine productivity Improvement metrics Master checklists and forms Developing activity boards Appendices containing examples of maintenance training materials For a PDF file with the preface and table of contents click here. For a PDF file with the first chapter click here.


Live Cell Imaging

Live Cell Imaging

Author: Dmitri Papkovsky

Publisher: Humana Press

Published: 2009-12-17

Total Pages: 0

ISBN-13: 9781607614036

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Now a routine tool in biomedical and life science research, live cell imaging has made major progress enabling this core biochemical, cell, and molecular biology technique to become even more powerful, versatile, and affordable. In Live Cell Imaging: Methods and Protocols, a panel of expert contributors provide a comprehensive compendium of experimental approaches to live cell imaging in the form of several overview chapters followed by representative examples and case studies covering different aspects of the most current methodology. By examining a range of state-of-the-art protocols extensively validated in complex biological studies, this volume highlights new experimental and instrumental opportunities and helps researchers to select appropriate imaging methods for their specific biological questions and measurement tasks. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Live Cell Imaging: Methods and Protocols promises to contribute greatly to the further development and dissemination of this fundamentally important technology which spans across many disciplines including molecular and cell biology, chemistry, physics, optics, engineering, cell physiology, and medicine.


Advanced Environmental Monitoring

Advanced Environmental Monitoring

Author: Young Kim

Publisher: Springer Science & Business Media

Published: 2007-10-31

Total Pages: 437

ISBN-13: 1402063644

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This book deals with recent developments and applications of environmental monitoring technologies, with emphasis on rapidly progressing optical and biological methods. Written by worldwide experts, this book will be of interest to environmental scientists in academia, research institutes, industry and the government.


Clinical Toxicology Testing

Clinical Toxicology Testing

Author: Barbarajean Magnani

Publisher:

Published: 2020

Total Pages: 375

ISBN-13: 9781941096505

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"A comprehensive overview of clinical laboratory toxicology services and analytes"--