Metallointercalators

Metallointercalators

Author: Janice Aldrich-Wright

Publisher: Springer

Published: 2011-04-06

Total Pages: 449

ISBN-13: 3211990798

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A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery.


National JobBank 2010

National JobBank 2010

Author: Adams Media

Publisher: Simon and Schuster

Published: 2010-09-15

Total Pages: 3655

ISBN-13: 1440513171

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Alphabetically arranged by state, this indispensable annual director to over 21,000 employers offers a variety of pertienent contact, business, and occupational data. - American Library Association, Business Reference and Services Section (BRASS) Completely updated to include the latest industries and employers, this guide includes complete profiles of more than 20,000 employers nationwide featuring: Full company name, address, phone numbers, and website/e-mail addresses Contacts for professional hiring A description of the companys products or services Profiles may also include: Listings of professional positions advertised Other locations Number of employees Internships offered


Annual Report

Annual Report

Author: Iowa Community Economic Betterment Account Program

Publisher:

Published: 2001

Total Pages: 28

ISBN-13:

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National Biotech Register

National Biotech Register

Author:

Publisher:

Published: 1992

Total Pages: 158

ISBN-13:

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Covers companies involved in biotech research and product development. Includes a classified index to research areas and product development by subject and state. Also includes a list of leading trademarks and brandnames with name and address of manufacturer.


The origin, function and diagnostic potential of extracellular microRNA in human body fluids

The origin, function and diagnostic potential of extracellular microRNA in human body fluids

Author: Andrey Turchinovich

Publisher: Frontiers E-books

Published: 2014-07-28

Total Pages: 115

ISBN-13: 2889192423

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Short non-coding RNA molecules, microRNAs (miRNAs), post-transcriptionally regulate gene expression in living cells. In recent years, miRNAs have been found in a wide spectrum of mammalian body fluids including blood plasma, saliva, urine, milk, seminal plasma, tears and amniotic fluid as extracellular circulating nuclease-resistant entities. The changes in miRNA spectra observed in certain fluids correlated with various pathological conditions suggesting that extracellular miRNAs can serve as informative biomarkers for certain diseases including cancer. However, the mechanism of generation and a biological role of extracellular miRNAs remain unclear. The current theories regarding extracellular miRNA origin and function suggest that these miRNAs can be either non-specific ‘by-products’ of cellular activity and cell death or specifically released cell-cell signaling messengers. The goal of this Research Topic is to bring together up-to-date knowledge about the extracellular miRNA and its role in disease diagnostics and, possibly, inter-cellular communication.