Combining Simulations, Theory, and Experiments into Multiscale Models of Biological Events
Author: Fabio Trovato
Publisher: Frontiers Media SA
Published: 2022-01-11
Total Pages: 322
ISBN-13: 2889740250
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Physical Virology
Author: Urs F. Greber
Publisher: Springer
Published: 2019-07-17
Total Pages: 235
ISBN-13: 303014741X
DOWNLOAD EBOOKThis book explores a new challenge in virology: to understand how physical properties of virus particles (virions) and viruses (infected cells) affect the course of an infection. Insights from the emerging field of physical virology will contribute to understanding of the physical nature of viruses and cells, and will open new ways for anti-viral interference. Nine chapters and an editorial written by physicists, chemists, biologists and computational experts describe how virions serve as trail blazers in uncharted territory of cells. The authors outline how particles change in composition as they interact with host cells. Such virus dynamics are crucial for virus entry into cells and infection. It influences the modern concepts of virus-host interactions, viral lineages and evolution. The volume gives numerous up-to-date examples of modern virology and provides a fascinating read for researchers, clinicians and students in the field of infectious diseases.
Advancing Theory for Kinetics and Dynamics of Complex, Many-Dimensional Systems
Author: Tamiki Komatsuzaki
Publisher: John Wiley & Sons
Published: 2011-07-07
Total Pages: 332
ISBN-13: 1118087828
DOWNLOAD EBOOKThis series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 145 in the series continues to report recent advances with significant, up-to-date chapters by internationally recognized researchers.
Multiscale Analysis and Nonlinear Dynamics
Author: Misha Meyer Pesenson
Publisher: John Wiley & Sons
Published: 2013-09-13
Total Pages: 307
ISBN-13: 352767165X
DOWNLOAD EBOOKSince modeling multiscale phenomena in systems biology and neuroscience is a highly interdisciplinary task, the editor of the book invited experts in bio-engineering, chemistry, cardiology, neuroscience, computer science, and applied mathematics, to provide their perspectives. Each chapter is a window into the current state of the art in the areas of research discussed and the book is intended for advanced researchers interested in recent developments in these fields. While multiscale analysis is the major integrating theme of the book, its subtitle does not call for bridging the scales from genes to behavior, but rather stresses the unifying perspective offered by the concepts referred to in the title. It is believed that the interdisciplinary approach adopted here will be beneficial for all the above mentioned fields.
Multiscale Modeling of Cancer
Author: Vittorio Cristini
Publisher: Cambridge University Press
Published: 2010-09-09
Total Pages: 299
ISBN-13: 1139491504
DOWNLOAD EBOOKMathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
Advances in data-driven approaches and modeling of complex systems
Author: Mohd Hafiz Mohd
Publisher: Frontiers Media SA
Published: 2023-06-27
Total Pages: 133
ISBN-13: 2832526659
DOWNLOAD EBOOKMultiscale Dynamics Simulations: Nano and Nano-bio Systems in Complex Environments
Author: Dennis R. Salahub
Publisher: Royal Society of Chemistry
Published: 2021-10-01
Total Pages: 411
ISBN-13: 1839161787
DOWNLOAD EBOOKFocusing on key methodological breakthroughs in the field, this book provides newcomers with a comprehensive menu of multiscale modelling options.
Multiscale Biomechanical Modeling of the Brain
Author: Mark F. Horstemeyer
Publisher: Elsevier
Published: 2021-11-02
Total Pages: 276
ISBN-13: 0128181443
DOWNLOAD EBOOKMultiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection. The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. Presents concepts in a theoretical and thermodynamic framework for each length scale Teaches readers not only how to use an existing multiscale model for each brain but also how to develop a new multiscale model Takes an integrated experimental-computational approach and gives structured multiscale coverage of the problems
Dynamics of Systems on the Nanoscale
Author: Ilia A. Solov'yov
Publisher: Springer Nature
Published: 2022-06-03
Total Pages: 554
ISBN-13: 3030992918
DOWNLOAD EBOOKThis book presents the structure formation and dynamics of animate and inanimate matter on the nanometre scale. This is a new interdisciplinary field known as Meso-Bio-Nano (MBN) science that lies at the intersection of physics, chemistry, biology and material science. Special attention in the book is devoted to investigations of the structure, properties and dynamics of complex MBN systems by means of photonic, electronic, heavy particle and atomic collisions. This includes problems of fusion and fission, fragmentation, surfaces and interfaces, reactivity, nanoscale phase and morphological transitions, irradiation-driven transformations of complex molecular systems, collective electron excitations, radiation damage and biodamage, channeling phenomena and many more. Emphasis in the book is placed on the theoretical and computational physics research advances in these areas and related state-of-the-art experiments. Particular attention in the book is devoted to the utilization of advanced computational techniques and high-performance computing in studies of the dynamics of systems.
Multiscale Dynamics Simulations
Author: Dennis R. Salahub
Publisher: Royal Society of Chemistry
Published: 2021-09-24
Total Pages: 411
ISBN-13: 1839164670
DOWNLOAD EBOOKOver the past decade, great strides have been taken in developing methodologies that can treat more and more complex nano- and nano-bio systems embedded in complex environments. Multiscale Dynamics Simulations covers methods including DFT/MM-MD, DFTB and semi-empirical QM/MM-MD, DFT/MMPOL as well as Machine-learning approaches to all of the above. Focusing on key methodological breakthroughs in the field, this book provides newcomers with a comprehensive menu of multiscale modelling options so that they can better chart their course in the nano/bio world.
