Cold Spring Harbor Monograph Series
Author:
Publisher:
Published: 1903
Total Pages: 314
ISBN-13:
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Telomeres
Author: Titia De Lange
Publisher:
Published: 2006
Total Pages: 598
ISBN-13:
DOWNLOAD EBOOKAn up-to-date survey of the current exciting state of telomere biology. Telomeres – specialized structures found at the ends of chromosomes – are essential for maintaining the integrity of chromosomes and their faithful duplication during cell division. Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.
Cell Growth
Author: Michael N. Hall
Publisher: CSHL Press
Published: 2004
Total Pages: 668
ISBN-13: 9780879696726
DOWNLOAD EBOOKRecent breakthroughs in the field of cell growth, particularly in the control of cell size, are reviewed by experts in the three major divisions of the field: growth of individual cells, growth of organs, and regulation of cell growth in the contexts of development and cell division. This book is an introductory overview of the field and should be adaptable as a textbook.
C. Elegans II
Author: Donald L. Riddle
Publisher: Firefly Books
Published: 1997
Total Pages: 1252
ISBN-13: 9780879695323
DOWNLOAD EBOOKDefines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
The Nematode Caenorhabditis Elegans
Author: William Barry Wood
Publisher:
Published: 1988
Total Pages: 694
ISBN-13:
DOWNLOAD EBOOKWe Can Sleep Later
Author: Alfred Day Hershey
Publisher: CSHL Press
Published: 2000
Total Pages: 396
ISBN-13: 9780879695675
DOWNLOAD EBOOKAn absorbing portrait of the pioneering molecular biologist best known for demonstrating that DNA is the genetic component of phages, through essays and reminiscences from twenty–three distinguished scientists whose work and careers were influenced by the man and his science.
Essentials of Glycobiology
Author: Ajit Varki
Publisher: CSHL Press
Published: 1999
Total Pages: 694
ISBN-13: 9780879696818
DOWNLOAD EBOOKSugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
DNA Replication and Human Disease
Author: Melvin L. DePamphilis
Publisher: CSHL Press
Published: 2006
Total Pages: 814
ISBN-13: 0879697660
DOWNLOAD EBOOKAt least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease.
Molecular Biology of Aging
Author: Leonard Guarente
Publisher: CSHL Press
Published: 2008
Total Pages: 610
ISBN-13: 0879698241
DOWNLOAD EBOOKThis volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer.
Epigenetics
Author: C. David Allis
Publisher: CSHL Press
Published: 2007
Total Pages: 503
ISBN-13: 0879697245
DOWNLOAD EBOOKThe regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.
