Coenzyme B12 Enzymes Part B
Coenzyme B12 Enzymes Part B

Author:

Publisher: Academic Press

Published: 2022-05-27

Total Pages: 386

ISBN-13: 0323955584

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Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-dependent enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology series Includes the latest information on B12 Enzymes

Coenzyme B12 Enzymes Part A
Coenzyme B12 Enzymes Part A

Author:

Publisher: Academic Press

Published: 2022-05-17

Total Pages: 392

ISBN-13: 0323915922

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B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-dependent methionine synthase, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Includes the latest information on B12 Enzymes

Vitamin B 12 and B 12-Proteins
Vitamin B 12 and B 12-Proteins

Author: Bernhard Kräutler

Publisher: Wiley-VCH

Published: 1998-03-09

Total Pages: 568

ISBN-13:

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This text reviews the important developments in the "B12-field" with regard to biological, chemical, pharmaceutical and medicinal aspects. Topics of particular interest include: biosynthesis of vitamin B12; B12-catalyzed enzymatic reactions and their mechanisms; and structural B12-chemistry

The Vitamin Co-Factors of Enzyme Systems
The Vitamin Co-Factors of Enzyme Systems

Author: F. A. Robinson

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 907

ISBN-13: 1483195716

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The Vitamin Co-Factors of Enzyme Systems provides a systematic account of the vitamin B complex, which play a fundamental role in a variety of biochemical reactions. This book reviews the vitamin B group in terms of their significance in enzymes reactions. Organized into 11 chapters, this book begins with an overview of the processes by which the main nutrients are broken down into simpler components. This text then explores the existence in foodstuffs of substances essential for the proper functioning of the animal organism. Other chapters consider the synthetic method of producing a commercially important chemical to be displaced by a method based on its isolation from natural sources. This book discusses as well the effect of various vitamin deficiencies in human beings. The final chapter deals with the series of changes that represents the biochemical reactions that occur during the contraction of muscles. This book is a valuable resource for biochemists and clinicians.

Coenzyme B12 Enzymes Part A
Coenzyme B12 Enzymes Part A

Author:

Publisher: Academic Press

Published: 2022-05-19

Total Pages: 0

ISBN-13: 9780323915915

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B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-dependent methionine synthase, and much more.

Chemistry of Plant Phosphorus Compounds
Chemistry of Plant Phosphorus Compounds

Author: Arlen Frank

Publisher: Elsevier

Published: 2013-06-03

Total Pages: 688

ISBN-13: 0124072232

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Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae). The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals. Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors. Comprehensive examination of phosphorus compounds found in plants Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis Easy to use indexes of plants, compounds and authors

Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition
Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition

Author: Richard B. Silverman

Publisher: Elsevier

Published: 2002-03-07

Total Pages: 736

ISBN-13: 0080513360

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The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style

Laboratory Assessment of Vitamin Status
Laboratory Assessment of Vitamin Status

Author: Dominic J. Harrington

Publisher: Academic Press

Published: 2018-11-28

Total Pages: 340

ISBN-13: 0128130512

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Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status Informs laboratories looking for third party providers of specialist investigations Provides an essential overview of reference ranges for each vitamin

The Purple Phototrophic Bacteria
The Purple Phototrophic Bacteria

Author: C.N. Hunter

Publisher: Springer Science & Business Media

Published: 2008-10-11

Total Pages: 1013

ISBN-13: 1402088159

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Here is a comprehensive survey of all aspects of these fascinating bacteria, metabolically the most versatile organisms on Earth. It compiles 48 chapters written by leading experts, who highlight the huge progress made in studies of these bacteria since 1995.

Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants
Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants

Author: Erick J. Vandamme

Publisher: John Wiley & Sons

Published: 2016-04-25

Total Pages: 580

ISBN-13: 3527337342

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Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.