Scientific and Medical Aspects of Human Reproductive Cloning

Scientific and Medical Aspects of Human Reproductive Cloning

Author: National Research Council

Publisher: National Academies Press

Published: 2002-06-17

Total Pages: 295

ISBN-13: 0309076374

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Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.


Clone

Clone

Author: David Schulner

Publisher: Clone Tp

Published: 2013

Total Pages: 0

ISBN-13: 9781607068303

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Luke Taylor's true nature has been revealed, but his fight to rescue his wife and newborn daughter is just beginning. Now that Beta and the second generation of clones have been unleashed, can Luke survive against his younger, stronger, and more ruthless selves?


Understanding Cloning

Understanding Cloning

Author: Jay D. Gralla

Publisher: Penguin

Published: 2004

Total Pages: 352

ISBN-13: 9781592571482

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The most important technology of the 21st century. Do a double-take with this one-of-a-kind guide. One of technology's most awe-inspiring and hotly-debated topics-cloning-is made clearer here than anywhere else. It runs the gamut from genetic- and bioengineering, to an even handed analysis of the moral, political, and ethical issues surrounding these technologies. € Claims of cloned babies, the Human Genome Project, and cryogenics continue to create headlines and spur debate € Congress will soon decide whether the federal government should have a say about cloning human cells for medical research


The Cloning Sourcebook

The Cloning Sourcebook

Author: Arlene Judith Klotzko

Publisher: Oxford University Press

Published: 2003-09-25

Total Pages: 374

ISBN-13: 0199731039

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Animal cloning has developed quickly since the birth of Dolly the sheep. Yet many of the first questions to be raised still need to be answered. What do Dolly and her fellow mouse, cow, pig, goat and monkey clones mean for science? And for society? Why do so many people respond so fearfully to cloning? What are the ethical issues raised by cloning animals, and in the future, humans? How are the makers of public policy coping with the stunning fact that an entire animal can be reconstructed from a single adult cell? And that humans might well be next? The Cloning Source Book addresses all of these questions in a way that is unique in the cloning literature, by grounding what is effectively an interdisciplinary conversation in solid science. In the first section of the book, the key scientists responsible for the early and crucial developments in cloning speak to us directly, and other scientists evaluate and comment on these developments. The second section explores the context of cloning and includes sociological, mythological, and historical perspectives on science, ethics, and policy. The authors also examine the media's treatment of the Dolly story and its aftermath, both in the United States and in Britain. The third section, on ethics, contains a broad range of papers written by some of the major commentators in the field. The fourth section addresses legal and policy issues. It features individual and collective contributions by those who have actually shaped public policy on reproductive cloning, therapeutic cloning, and similarly contentious bioethical issues in the United States, Britain, and the European Union. Animal cloning continues for agricultural and medicinal purposes, the latter in combination with transgenics. Human cloning for therapeutic purposes has recently been made legal in Britain. The goal is to produce an early embryo and then derive stem cells that are immunologically matched to the donor. Two human reproductive cloning projects have been announced, and there are almost certainly others about which we know nothing. Sooner or later a cloned human will be born. Many lessons can be learned from the cloning experience. Most importantly, there needs to be a public conversation about the permissible uses of new and morally murky technologies. Scientists, journalists, ethicists and policy makers all have roles to play, but cutting-edge science is everybody's business. The Cloning Sourcebook provides the tools required for us to participate in shaping our own futures.


Code Clone Analysis

Code Clone Analysis

Author: Katsuro Inoue

Publisher: Springer Nature

Published: 2021-08-03

Total Pages: 236

ISBN-13: 9811619271

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This is the first book organized around code clone analysis. To cover the broad studies of code clone analysis, this book selects past research results that are important to the progress of the field and updates them with new results and future directions. The first chapter provides an introduction for readers who are inexperienced in the foundation of code clone analysis, defines clones and related terms, and discusses the classification of clones. The chapters that follow are categorized into three main parts to present 1) major tools for code clone analysis, 2) fundamental topics such as evaluation benchmarks, clone visualization, code clone searches, and code similarities, and 3) applications to actual problems. Each chapter includes a valuable reference list that will help readers to achieve a comprehensive understanding of this diverse field and to catch up with the latest research results. Code clone analysis relies heavily on computer science theories such as pattern matching algorithms, computer language, and software metrics. Consequently, code clone analysis can be applied to a variety of real-world tasks in software development and maintenance such as bug finding and program refactoring. This book will also be useful in designing an effective curriculum that combines theory and application of code clone analysis in university software engineering courses.


Empirical Research towards a Relevance Assessment of Software Clones

Empirical Research towards a Relevance Assessment of Software Clones

Author: Saman Bazrafshan

Publisher: Logos Verlag Berlin GmbH

Published: 2017-06-30

Total Pages: 270

ISBN-13: 3832545093

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Redundancies in program source code - software clones - are a common phenomenon. Although it is often claimed that software clones decrease the maintainability of software systems and need to be managed, research in the last couple of years showed that not all clones can be considered harmful. A sophisticated assessment of the relevance of software clones and a cost-benefit analysis of clone management is needed to gain a better understanding of cloning and whether it is truly a harmful phenomenon. This thesis introduces techniques to model, analyze, and evaluate versatile aspects of software clone evolution within the history of a system. We present a mapping of non-identical clones across multiple versions of a system, that avoids possible ambiguities of previous approaches. Though processing more data to determine the context of each clone to avoid an ambiguous mapping, the approach is shown to be efficient and applicable to large systems for a retrospective analysis of software clone evolution. The approach has been used in several studies to gain insights into the phenomenon of cloning in open-source as well as industrial software systems. Our results show that non-identical clones require more attention regarding clone management compared to identical clones as they are the dominating clone type for the main share of our subject systems. Using the evolution model to investigate costs and benefits of refactorings that remove clones, we conclude that clone removals could not reduce maintenance costs for most systems under study.


Gene Cloning and Manipulation

Gene Cloning and Manipulation

Author: Christopher Howe

Publisher: Cambridge University Press

Published: 2007-07-12

Total Pages: 250

ISBN-13: 1139463586

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Updated to reflect advances in the field, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Written for advanced undergraduates, graduates and scientists who want to use this technology, emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations. An introduction to the basic biochemical principles is presented first. Then PCR and cloning using E. coli hosts and plasmid, phage and hybrid vectors are described, followed by the generation and screening of libraries and how to modify, inactivate or express cloned sequences. Finally genetic manipulation in a range of other organisms is discussed, including other bacteria, fungi, algae and plants, insects and mammals. A series of 'real-life' biological problems are also presented to enable readers to assess their understanding of the material and to prepare for exams.


A Practical Hand Book of Genes to Clones -Manual

A Practical Hand Book of Genes to Clones -Manual

Author: Dr. B. Usharani

Publisher: Notion Press

Published: 2019-04-05

Total Pages: 283

ISBN-13: 164546511X

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To the student: There are a number of features to help you learn as you read. Each section is summarized with a bulleted list of key concepts. Key terms are highlighted in boldface in the text and defined in the margin for easy reference. Each chapter focuses on historical perspectives, methods, techniques and medical applications. Finally, each chapter concludes with suggested further reading, a brief list of current reviews and pivotal papers to supplement and reinforce the chapter content.


Effective Java

Effective Java

Author: Joshua Bloch

Publisher: Addison-Wesley Professional

Published: 2008-05-08

Total Pages: 375

ISBN-13: 0132778041

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Are you looking for a deeper understanding of the JavaTM programming language so that you can write code that is clearer, more correct, more robust, and more reusable? Look no further! Effective JavaTM, Second Edition, brings together seventy-eight indispensable programmer’s rules of thumb: working, best-practice solutions for the programming challenges you encounter every day. This highly anticipated new edition of the classic, Jolt Award-winning work has been thoroughly updated to cover Java SE 5 and Java SE 6 features introduced since the first edition. Bloch explores new design patterns and language idioms, showing you how to make the most of features ranging from generics to enums, annotations to autoboxing. Each chapter in the book consists of several “items” presented in the form of a short, standalone essay that provides specific advice, insight into Java platform subtleties, and outstanding code examples. The comprehensive descriptions and explanations for each item illuminate what to do, what not to do, and why. Highlights include: New coverage of generics, enums, annotations, autoboxing, the for-each loop, varargs, concurrency utilities, and much more Updated techniques and best practices on classic topics, including objects, classes, libraries, methods, and serialization How to avoid the traps and pitfalls of commonly misunderstood subtleties of the language Focus on the language and its most fundamental libraries: java.lang, java.util, and, to a lesser extent, java.util.concurrent and java.io Simply put, Effective JavaTM, Second Edition, presents the most practical, authoritative guidelines available for writing efficient, well-designed programs.