Repair and Redesign of Physiological Systems

Repair and Redesign of Physiological Systems

Author: Mark A. Atherton

Publisher: WIT Press

Published: 2008-07-15

Total Pages: 305

ISBN-13: 1845640969

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In this volume the author highlights the role of engineering and relevant mathematics in medicine. Like engineering systems, human physiology can wear out or fail to an extent where it requires a clinical interventionist to repair or even redesign the system. There is a long tradition amongst clinicians of working with engineers and mathematicians, and this volume continues the theme with modern developments. Hence chapters deal with vascular surgery planning, cardiac and vascular devices, immunotherapeutics, plus nasal and dental repair. More generically, some of these chapters relate to preserving the integrity of the human 'surface structure', as well as the challenges in computer modeling the complexities and multiscale nature of the human physiome.


The Digital Patient

The Digital Patient

Author: C. D. Combs

Publisher: John Wiley & Sons

Published: 2015-12-11

Total Pages: 331

ISBN-13: 1118952774

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A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.


Modeling of Physiological Flows

Modeling of Physiological Flows

Author: Davide Ambrosi

Publisher: Springer Science & Business Media

Published: 2012-10-31

Total Pages: 418

ISBN-13: 8847019354

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This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.


Principles of Genetics and Molecular Epidemiology

Principles of Genetics and Molecular Epidemiology

Author: Juan Carlos Gomez-Verjan

Publisher: Springer Nature

Published: 2022-01-28

Total Pages: 214

ISBN-13: 3030896013

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This book covers some of the most novel genetic and genomic concepts in epidemiology, such as geospatial statistics and systems biology from a clinical point of view by explaining molecular applications with accessible human studies. Featuring a comprehensive table of contents, it includes chapters from genomics and epidemiology surveillance to transcriptomics and alternative splicing principles. Across 17 well-organized chapters, this book meets attempt to explain easily to clinicians and students with basic principles of the genetics, genomics, molecular biology and its applications to epidemiology and public health. The text is distinct from other literature on the market because it covers useful genomic tools applied in epidemiology for clinicians who may not be experts in this branch of health science. Principles of Genetics and Molecular Epidemiology demystifies the idea that biomedicine is far from being applied in both epidemiology and clinical practice.


Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2010

Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2010

Author: Tianzi Jiang

Publisher: Springer Science & Business Media

Published: 2010-09

Total Pages: 751

ISBN-13: 3642157041

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The three-volume set LNCS 6361, 6362 and 6363 constitutes the refereed proceedings of the 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010, held in Beijing, China, in September 2010. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 786 submissions for presentation in three volumes. The first volume includes 84 papers organized in topical sections on computer-aided diagnosis, planning and guidance of interventions, image segmentation, image reconstruction and restoration, functional and diffusion-weighted MRI, modeling and simulation, instrument and patient localization and tracking, quantitative image analysis, image registration, computational and interventional cardiology, and diffusion tensor MR imaging and analysis.


Systems Biology and Livestock Science

Systems Biology and Livestock Science

Author: Marinus te Pas

Publisher: John Wiley & Sons

Published: 2011-09-23

Total Pages: 340

ISBN-13: 0470962968

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Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.


Modeling & Imaging of Bioelectrical Activity

Modeling & Imaging of Bioelectrical Activity

Author: Bin He

Publisher: Springer Science & Business Media

Published: 2010-07-03

Total Pages: 332

ISBN-13: 0387499636

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Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.


Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007

Author: Nicholas Ayache

Publisher: Springer

Published: 2007-11-22

Total Pages: 1044

ISBN-13: 3540757570

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This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this first volume includes diffusion tensor imaging and computing, cardiac imaging and robotics, image segmentation and classification, image guided intervention and robotics, innovative clinical and biological applications, brain atlas computing, and simulation of therapy.


Multiscale Modeling of the Skeletal System

Multiscale Modeling of the Skeletal System

Author: Marco Viceconti

Publisher: Cambridge University Press

Published: 2012

Total Pages: 223

ISBN-13: 0521769507

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Systematically working from the whole body down to cellular levels, this book presents a multiscale, integrative approach to skeletal research.