This book is a practical guide to the diagnosis and management of tuberculosis. Presented in a step by step approach, the text provides the latest information in the specialty, guiding clinicians through the history of the disease, its epidemiology, pathogenesis and pathology, to clinical presentation, imaging, diagnosis, and treatment options. The book is enhanced by illustrations and figures, and provides a clear understanding of the management of the disease from a global perspective and the challenges associated with tuberculosis care. Key points Practical guide to diagnosis and management of tuberculosis Presented in a step by step approach, providing latest information in the field Includes illustrations and figures to assist learning Provides clear understanding of challenges associated with tuberculosis care
This is a guide to the diagnosis of all forms of tuberculosis (TB). The second edition of the text includes a rewritten and enlarged section on HIV infection in relation to TB as well as the recommendations from experts from the World Health Organization and the International Union against Tuberculosis and Lung Disease. An outline of the WHO DOTS (Directly Observed Treatment Shortcourse) programme is included and the whole text reviewed and updated. Case studies are used to demonstrate points raised.
Over 250 diagnostic and treatment algorithms over 900 topics providing clinical guidance current evidence-based designations highlighted in each topic at-a-glance format with concise and bulleted text, ICD-10 codes, dsm-5criteria quick information to help in diagnosis, treatment selection and medication dosing easy-to-use reference at point of care providing quick answer to a direct clinical question.
1. History 2. Epidemiology of Tuberculosis: Global Perspective 3. Pathology of Tuberculosis 4. The Mycobacteria 5. Immunology of Tuberculosis 6. Genetic Susceptibility Parameters in Tuberculosis 7. Genetics of Susceptibility to Tuberculosis 8. Laboratory Diagnosis of Tuberculosis: Best Practices and Current Policies 9. Roentgenographic Manifestations of Pulmonary and Extra-pulmonary Tuberculosis 10. Pulmonary Tuberculosis 11. Lower Lung Field Tuberculosis 12. Endobronchial Tuberculosis 13. Tuberculosis Pleural Effusion 14. Silicotuberculosis 15. Abdominal Tuberculosis 16. Granulomatous Hepatitis 17. Neurological Tuberculosis 18. Tuberculosis and Heart 19. Skeletal Tuberculosis 20. Musculoskeletal Manifestations of Tuberculosis 21. Cutaneous Tuberculosis 22. Lymph Node Tuberculosis 23. Tuberculosis in Head and Neck 24. Ocular Tuberculosis 25. Tuberculosis in Pregnancy 26. Female Genital Tuberculosis 27. Genitourinary Tuberculosis 28. Tuberculosis in Chronic Kidney Disease 29. Disseminated/Miliary Tuberculosis 30. Tuberculosis at Uncommon Body Sites 31. Complications of Pulmonary Tuberculosis 32. Tuberculosis and Acute Respiratory Distress Syndrome 33. Haematological Manifestations of Tuberculosis 34. Endocrine Implications of Tuberculosis 35. Tuberculosis and Human Immunodeficiency Virus Infection 36. Tuberculosis in Children 37. Surgical Aspects of Childhood Tuberculosis 38. Tuberculosis in the Elderly 39. Tuberculosis in Health Care Workers 40. Nutrition and Tuberculosis 41. Nontuberculous Mycobacterial Infections 42. Drug-resistant Tuberculosis 43. Antituberculosis Drug Resistance Surveillance 44. Treatment of Tuberculosis 45. Hepatotoxicity Associated with Anti-tuberculosis Treatment 46. Surgery for Pleuropulmonary Tuberculosis 47. Stopping TB: The Role of DOTS in Global Tuberculosis Control 48. The Role of Medical Colleges in Tuberculosis Control 49. Public-Private Mix for TB Care 50. Building Partnerships for Tuberculosis Control 51. Integrating Community-based Tuberculosis Activities into the Work of Non-governmental and other Civil Society Organisations [The ENGAGE-TB Approach] 52. WHOÂ's New End TB Strategy 53. The Revised National Tuberculosis Control Programme 54. Tuberculosis Vaccine Development: A Current Perspective 55. Ethical and Legal Issues in Tuberculosis Control 56. Airborne Tuberculosis Transmission and Infection Control Strategies 57. Standards for TB Care in India 58. International Standards for Tuberculosis Care 59. Index-TB Guidelines [Guidelines on Extra-pulmonary Tuberculosis for India] Index
The Global Tuberculosis Programme of the World Health Organization (WHO) convened a virtual technical consultation on “Innovative Clinical Trial Designs for Development of New TB Treatments” on 5 days between 20 August and 13 October 2021. The main objective of the meeting was to establish evidence-based approaches to trial designs and use of data to inform policy guidance of new regimens for the treatment of TB with the view to accelerate future regimen development. The consultation brought together researchers, academics, technical partners, TB drugs and regimens developers including pharmaceutical industry, trialists, regulators, guideline developers, programme managers, nongovernmental organizations and civil society.
Part of the Clinical Focus series, this book is a comprehensive guide to the diagnosis and treatment of tuberculosis. The new volume is highly illustrated with tables and images and written by an internationally recognised editor and author team.
Written by skilled specialists in the field of interventional pulmonology, the new Second Edition thoroughly explores the latest advancements, newest therapies, and diagnostic techniques in interventional pulmonary medicine. Using guidelines to ensure maximum quality and efficiency in patient care, this concise text is a must-have resource for all
BACKGROUND: Latent tuberculosis infection (LTBI), defined as a state of persistent immune response to prior-acquired Mycobacterium tuberculosis antigens without evidence of clinically manifested active TB, affects about one-third of the world's population. Approximately 10% of people with LTBI will develop active TB disease in their lifetime, with the majority developing it within the first five years after initial infection. Currently available treatments have an efficacy ranging from 60% to 90%. Systematic testing and treatment of LTBI in at-risk populations is a critical component of WHO's eight-point framework adapted from the End TB Strategy to target pre-elimination and, ultimately, elimination in low incidence countries. OVERVIEW: Recognizing the importance of expanding the response to LTBI, in 2014 WHO developed Guidelines on the Management of Latent Tuberculosis Infection. The guidelines are primarily targeted at high-income or upper middle-income countries with an estimated TB incidence rate of less than 100 per 100 000 population, because they are most likely to benefit from it due to their current TB epidemiology and resource availability. The overall objective of the guidelines is to provide public health approach guidance on evidence-based practices for testing, treating and managing LTBI in individuals with the highest risk of progression to active disease. Specific objectives include identifying and prioritizing at-risk population groups for targeted intervention of LTBI testing and treatment, including defining an algorithm, and recommending specific treatment options. The guidelines are expected to provide the basis and rationale for the development of national guidelines for LTBI management based on available resources, epidemiology of TB including intensity of transmission, the health-care delivery system of the country, and other national and local determinants.
This is the second edition of a reference work aimed at all those concerned with dealing with tuberculosis control in developing countries. The book follows in the tradition of Kurt Toman's original work in this field, with the text set out in a question and answer format, grouped under three headings: case detection; treatment, and monitoring. The threat of tuberculosis is still potent, with two million deaths globally. This new edition, containing contributions from a number of experts in this field, addresses the resurgence of tuberculosis, and the emergence of multidrug-resistant bacilli, and the growth of HIV-infected individuals with tuberculosis, as well as recent scientific developments.
Clinical Respiratory Medicine provides practical guidance to help you more effectively diagnose and manage the full range of pulmonary disorders, including those seen in today's most challenging patient populations. In print and online, this medical reference book delivers the answers you need to ensure the best outcomes. - Better manage and treat patients with pulmonary disease with complete clinical coverage of the critical information relevant to your everyday practice, presented in a templated, user-friendly format. - Find critical information quickly with the help of diagnostic algorithms. - Test your knowledge of respiratory medicine with the help of 400 brand-new review questions. - Watch and learn. Over 25 videos of practical procedures are available online at www.expertconsult.com. - Thoroughly understand the needs and recognize co-morbidities of particular patient populations through entirely new chapters on lung structure, echocardiography, and obesity and its effects. - Access the latest research and advancements in lung cancer, benign tumors, and the importance of pulmonary physiology in understanding lung function and the disease processes that occur.
