The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
This is an updated, expanded new edition of Dr. Ruth Levine's renowned Pharmacology: Drug Actions and Reactions. It covers basic pharmacological principles and the general concepts of chemical-biological interactions and now includes important new material on molecular biology, updated clinical information, and added coverage of the newer drugs. For the sixth edition of this landmark book Dr. Levine is joined by co-authors Dr. Carol T. Walsh and Dr. Rochelle D. Schwartz-Bloom. Acclaimed for its exceptionally thorough coverage, superb presentation, and intelligent organization, the book guides you through the most elementary aspects of pharmacology to a sophisticated understanding of drug mechanisms. Each chapter contains a series of thought-provoking essay-type questions designed to test comprehension of the material in the chapter. In addition, a sufficient number of important, specific examples are included to illustrate the application of the principles. With the background provided by Pharmacology: Drug Actions and Reactions, Sixth Edition, you will be prepared to understand the actions of most individual drugs.
It was a warm, sunny morning in Rehovot. The sky was c1ear as it always is in June. As I walked to the Institute that morning, too many cars were passing by, too many people were hurrying onto the Institute's grounds. No one was smiling, acquaintances were recognized by a slight nod of the head. When I turned the corner, a few people already had gathered on the lawn in front of the Jacob Ziskind building. This number was to swell to thousands before the service was over. We were to be joined by the President of Israel, its first Prime Minister, many members of the cabinet, and other great, near-great, working colleagues, and residents of the town. The purpose of all this activity was written on everyone's face, and underlined by the casket that lay in the rotunda of the building. His wife was sitting there, his children, his brother, his students both past and present. One could hear the silence of the participants. I stood inside for a while, overlooking the rotunda. A long line of mourners filed by, offering their sympathies to the family. Suddenly a woman, dressed in black, fell to her knees in front 9f Rina, sobbing. It was the wife of the Japanese Ambassador to Israel. I moved to join the crowd outside. People were standing on the lawn, gingerly trying to avoid stepping on a flower.
Acetylcholine: An Approach to the Molecular Mechanism of Action is an in-depth study of neurotransmitter system, with much focus on acetylcholine and its action and the cholinergic synapse. The book, divided into seven chapters, covers the following topics: the function of the cholinergic synapse; the movement of ions across membranes; the excitatory postsynaptic potential; the nature of cholinoreceptors and cholinesterases; the structure of its active centers; and the pattern of arrangement of the receptors of the cholinoreceptive membrane. The book also covers the quantitative evaluation of the action of neurotransmitters; the reactive capacity of the acetylcholine molecule and its effects on nerve endings and nerve fibers; and the release of mediators and hormones. The text is recommended for those who specialize in the fields of biology, medicine, biochemistry, and pharmacology, especially those wish to study about the neurotransmitter system, cholinoreceptors, the cholinergic synapse, the acetylcholine, and its action.
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.
An Introduction to Mechanisms in Pharmacology and Therapeutics aims to provide some extra information and background reading on modes of action of drugs, but it is not meant to replace existing pharmacology textbooks. It also attempts to show the connection between cell biology and the practice of clinical medicine. This book is organized into 13 chapters that discuss drug-receptor interactions and the influence of drugs on the nervous, respiratory, circulatory, and alimentary systems. They also explain the concepts of pharmacogenetics, intracellular control mechanisms, chemotherapy, and the different types of drugs. This book will be of interest to preclinical and clinical medical students and those preparing for Bachelor of Science degree in Pharmacology and others interested in understanding how drugs work.
