A Practical Guide to the Study of Calcium in Living Cells
A Practical Guide to the Study of Calcium in Living Cells

Author: Richard Nuccitelli

Publisher: Academic Press

Published: 1994-03-10

Total Pages: 418

ISBN-13: 9780125641418

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A Practical Guide to the Study of Calcium in Living Cells describes popular techniques along with helpful do's and don't's and computer programs. The volume enables investigators to evaluate confocal images, use the latest dyes, and design Calcium buffers appropriate to their research needs. This book is designed for laboratory use by graduate students, technicians, and researchers in many disciplines, ranging from molecular to cellular levels of investigation. Describes techniques for detection of [Ca2+]I: Ca2+ - sensitive microelectrodes Fluorescent dyes Luminescent proteins Includes techniques for perturbing intracellular Ca2+ Covers detailed methodology plus problems and pitfalls of each technique Contains a practical guide to preparing Ca2+ buffers with an easy-to-use computer program Color plates illustrate techniques such as Confocal ratio-imaging Use of aequorin

Calcium in Biological Systems
Calcium in Biological Systems

Author: Ronald P. Rubin

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 697

ISBN-13: 1461323770

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This volume is based in part upon the proceedings of the Calcium Theme held during the 67th Annual Meeting of the Federation of American Societies for Experimental Biology, which took place in Chicago, AprillO-lS, 1983. The American Society for Pharmacology and Experimental Therapeutics had the primary responsibility for organizing the scientific program with the assistance of other member societies, including the American Physiology Society, American Association of Pathologists, and American Institute of Nutrition. The purpose of the Calcium Theme was to review progress in the diverse areas of investigation bearing on the ubiquitous role of calcium in biological systems. In addition to contributions from those participating in the Theme, this volume also includes a number of invited papers that were added to fill certain voids in topics covered. The authors were selected because they are investigators active in the mainstream of their particular research area, possessing the acumen to analyze cogently not only their own recent findings but also to relate these findings to their respective area. New information as well as reviews of current concepts generally highlight the individual contributions. Undoubtedly, some readers may argue with the emphasis made and/or the conclusions reached on individual topics. In such cases, other volumes will hopefully provide a forum for alternative points of view. Due to the broad scope of subjects covered and the large number of contributions, the papers have been arranged in three sections.

Calcium Entry Channels in Non-Excitable Cells
Calcium Entry Channels in Non-Excitable Cells

Author: Juliusz Ashot Kozak

Publisher: CRC Press

Published: 2017-07-14

Total Pages: 343

ISBN-13: 149875273X

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Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Signaling Mechanisms Regulating T Cell Diversity and Function
Signaling Mechanisms Regulating T Cell Diversity and Function

Author: Jonathan Soboloff

Publisher: CRC Press

Published: 2017-03-27

Total Pages: 258

ISBN-13: 149870509X

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T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.

Store-Operated Calcium Channels
Store-Operated Calcium Channels

Author:

Publisher: Academic Press

Published: 2013-07-24

Total Pages: 307

ISBN-13: 0124079385

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Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject

Calcium Orthophosphates
Calcium Orthophosphates

Author: Sergey V. Dorozhkin

Publisher: CRC Press

Published: 2012-06-04

Total Pages: 863

ISBN-13: 9814364177

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Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha

Lectins and Glycobiology
Lectins and Glycobiology

Author: Hans-Joachim Gabius

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 524

ISBN-13: 3642779441

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The intriguing complexity, precision, and regulation of the wide range of biologi cal processes is determined by intricate mechanisms of molecular recognition. Their nature is under intense scrutiny. In addition to the well-appreciated interac tion of proteins either with amino acid or nucleotide sequences, the investigation of their interplay with carbohydrate elements of cellular glycoconjugates current ly exerts increasing attraction. In the group of carbohydrate-binding proteins, lec tins are distinguished from antibodies or ligand-affecting enzymes, according to the most recent definition. The thorough analysis of their structure and function is considered as a focus to collect a critical mass of information for delineating details of a further array of biochemical processes with pivotal physiological im pact. Following an already century-long history of scientific description, reflected by subjectively chosen highlights (see the Brief History of Lectin Research at page VI), the excitement in glycobiological research that prevails today can easily be ex plained by our growing awareness of the multifarious significance of a sugar-code system of biological information. This present notion unmistakably has an im pact on lines of research in diverse disciplines like cell and molecular biology, histochemistry, or clinical sciences. It also prompts inherent practical questions such as how to obtain lectins, or how to employ them as instruments in various assay systems with the best possible results. Thus, this book is devoted intentionally to cover the techniques in different research fields that deal with lectins.

The Chemistry of Evolution
The Chemistry of Evolution

Author: R.J.P Williams

Publisher: Elsevier

Published: 2005-11-29

Total Pages: 495

ISBN-13: 0080460526

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Conventionally, evolution has always been described in terms of species. The Chemistry of Evolution takes a novel, not to say revolutionary, approach and examines the evolution of chemicals and the use and degradation of energy, coupled to the environment, as the drive behind it. The authors address the major changes of life from bacteria to man in a systematic and unavoidable sequence, reclassifying organisms as chemotypes. Written by the authors of the bestseller The Biological Chemistry of the Elements - The Inorganic Chemistry of Life (Oxford University Press, 1991), the clarity and precision of The Chemistry of Evolution plainly demonstrate that life is totally interactive with the environment. This exciting theory makes this work an essential addition to the academic and public library.* Provides a novel analysis of evolution in chemical terms* Stresses Systems Biology * Examines the connection between life and the environment, starting with the 'big bang' theory* Reorientates the chemistry of life by emphasising the need to analyse the functions of 20 chemical elements in all organisms

Electromagnetism, Quanta, And Electron Flow In The Electrophysiology Of Living Cells
Electromagnetism, Quanta, And Electron Flow In The Electrophysiology Of Living Cells

Author: Mark Noble

Publisher: World Scientific

Published: 2021-08-24

Total Pages: 220

ISBN-13: 9811234965

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Electrons are involved in all electrical phenomena, and living cells cannot be an exception. This book takes on a decidedly different approach to existing texts on electrophysiology, by considering electrical physiological processes from the viewpoint of electron flow, rather than the conventional notion of ion movement. It concisely describes the theoretical background of electron density and cellular voltage, before exploring thought-provoking questions such as the relationship between electrolyte distribution and transmembrane potential, and the source of electricity generation in living cells. A new electromagnetic theory of muscular function is presented, and all topics of relevance — including the electrophysiology of invertebrates, plants, fungi and bacteria — are comprehensively covered. Using plain language and more than 40 original illustrations, the author has designed each chapter to provide a succinct overview of an individual topic in a format that appeals to both the expert and the uninitiated. Electromagnetism, Quanta, and Electron Flow in the Electrophysiology of Living Cells proffers a refreshingly new way to understand a fascinatingly old subject.