C-X Bond Formation

C-X Bond Formation

Author: Arkadi Vigalok

Publisher: Springer

Published: 2010-06-30

Total Pages: 198

ISBN-13: 3642120733

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Contents: Kilian Muñiz: Transition Metal Catalyzed Electrophilic Halogenation of C-H bonds in alpha-Position to Carbonyl Groups; Arkadi Vigalok * and Ariela W Kaspi: Late Transition Metal-Mediated Formation of Carbon-Halogen Bonds; Paul Bichler and Jennifer A. Love*: Organometallic Approaches to Carbon-Sulfur Bond Formation; David S. Glueck: Recent Advances in Metal-Catalyzed C-P Bond Formation; Andrei N. Vedernikov: C-O Reductive Elimination from High Valent Pt and Pd Centers; Lukas Hintermann: Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes; Moris S. Eisen: Catalytic C-N, C-O and C-S bond formation promoted by organoactinide complexes.


C-X Bond Formation

C-X Bond Formation

Author: Arkadi Vigalok

Publisher: Springer Science & Business Media

Published: 2010-07-09

Total Pages: 198

ISBN-13: 3642120725

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Contents: Kilian Muñiz: Transition Metal Catalyzed Electrophilic Halogenation of C-H bonds in alpha-Position to Carbonyl Groups; Arkadi Vigalok * and Ariela W Kaspi: Late Transition Metal-Mediated Formation of Carbon-Halogen Bonds; Paul Bichler and Jennifer A. Love*: Organometallic Approaches to Carbon-Sulfur Bond Formation; David S. Glueck: Recent Advances in Metal-Catalyzed C-P Bond Formation; Andrei N. Vedernikov: C-O Reductive Elimination from High Valent Pt and Pd Centers; Lukas Hintermann: Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes; Moris S. Eisen: Catalytic C-N, C-O and C-S bond formation promoted by organoactinide complexes.


C-H and C-X Bond Functionalization

C-H and C-X Bond Functionalization

Author: Xavi Ribas

Publisher: Royal Society of Chemistry

Published: 2013

Total Pages: 489

ISBN-13: 1849735700

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Cross-coupling reactions involving C-H and C-X bond functionalisation are commonplace in natural product synthesis and natural products, therapeutic agents, biological probes, and advanced materials. Much attention has been given to understanding the mechanistic strategies used to achieve this, making this a hot topic in recent years. In this edited book, contributions from across the globe examine these strategies, with a particular focus on palladium and copper, as well as iron û an emerging element in this field. Reviewing the recent literature, the book presents an in-depth understanding of the field, guiding the reader to achieving the best synthetic strategies for aromatic functionalisation. Organic and Organometallic chemists, as well as natural product and pharmaceutical scientists, will find this an essential guide to a major transformation currently underway in synthetic chemistry.


Carbon-carbon, Carbon-nitrogen and Carbon-sulfur Bond Formation Reactions

Carbon-carbon, Carbon-nitrogen and Carbon-sulfur Bond Formation Reactions

Author: Ping Liu

Publisher: Scientific Research Publishing, Inc. USA

Published: 2023-07-13

Total Pages: 268

ISBN-13: 1649976453

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The construction of C-X (X = C, N, S) bonds is an important research content in the field of organic synthesis and drug preparation. Focusing on the green construction of the core skeleton of functional fine chemicals, the team has carried out research on green synthesis and catalytic reactions of fine chemicals, realized the effective synthesis of high value-added fine chemicals, and obtained a series of new systems of transition metal palladium and copper-catalyzed halogenated aromatic hydrocarbons involved in C-C and C-N coupling reactions; realized the efficient preparation of biphenyl, arylamine and aryl thioether compounds using water as solvent. Aiming at atomic economy, we realized the new method of direct C-H functionalization of arenes to construct C-C and C-S bond formation, as well as the construction of structurally complex functional molecular skeletons through one-pot multi-step reactions, laying a solid foundation for the application of fine organic synthesis technology in the fields of pharmaceutical intermediates, agrochemicals and optoelectronic materials, forming a distinctive research direction of fine chemical synthesis technology and it has formed a distinctive research direction of fine chemical synthesis technology and a stable R&D team, and improved the technical level of preparation of high value-added fine chemicals. He has published a total of 30 academic papers, including 27 SCI papers.


Conjugate Addition Reactions in Organic Synthesis

Conjugate Addition Reactions in Organic Synthesis

Author: P. Perlmutter

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 394

ISBN-13: 1483293785

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This book provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic synthesis. The book is organised in terms of the major classes of conjugate acceptors. Within each of these classes, the chemistry and applications of conjugate additions with several different categories of nucleophiles have been examined. Where several different nucleophiles achieve the same synthetic transformation, they are cross-referenced within the book and qualitative comparisons offered where appropriate. Examples of the use of conjugate additions in total synthesis of important molecules are included, with a special emphasis throughout the book on stereoselectivity. This will be a useful main text for graduate and postgraduate courses on conjugate addition reactions or the Michael reaction. It could also serve as a supplementary text for courses on topics such as the chemistry of organocopper reagents, enamines and carbanion chemistry.


Additions to C-X ?-Bonds

Additions to C-X ?-Bonds

Author: Barry M. Trost

Publisher: Elsevier

Published: 1992-09-08

Total Pages: 1012

ISBN-13: 0080912443

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Volume 1 provides a detailed survey of reactions that entail the 1,2-addition of nonstabilized carbanion equivalents of carbonyl, imino and thiocarbonyl functionality. Emphasis has been placed on those reagents that result in highly selective addition reactions. Methods are reported to select, for example, one carbonyl group over another in the same molecule, or to add preferentially a fragment to one (enantiotopic of diastereotopic) face of a carbonyl group. Processes that result from an initial addition to the C=X functional group, for example alkenations and rearrangements, are also covered in this volume.


Oxidative Cross-Coupling Reactions

Oxidative Cross-Coupling Reactions

Author: Aiwen Lei

Publisher: John Wiley & Sons

Published: 2016-08-12

Total Pages: 240

ISBN-13: 3527681019

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The first handbook on this emerging field provides a comprehensive overview of transition metal-catalyzed coupling reactions in the presence of an oxidant. Following an introduction to the general concept and mechanism of this reaction class, the team of authors presents chapters on C-C cross-coupling reactions using organometallic partners, C-Heteroatom bond forming reactions via oxidative couplings, and C-H couplings via C-H activation. The text also covers such groundbreaking topics as recent achievements in the fields of C-C and C-X bond formation reactions as well as C-H activation involving oxidative couplings. With its novel and concise approach towards important building blocks in organic chemistry and its focus on synthetic applications, this handbook is of great interest to all synthetic chemists in academia and industry alike.


Carbon-Carbon and Carbon-Heteroatom

Carbon-Carbon and Carbon-Heteroatom

Author: Rakesh Kumar Sharma

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2022-08-22

Total Pages: 398

ISBN-13: 3110759543

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Carbon-carbon and carbon-heteroatom bond-forming reactions are the backbone of synthetic organic chemistry. Scientists are constantly developing and improving these techniques in order to maximize the diversity of synthetically available molecules. These techniques must be developed in a sustainable manner in order to limit their environmental impact. This book highlights green carbon-carbon and carbon-heteroatom bond forming reactions.


Organometallic Chemistry

Organometallic Chemistry

Author: M. Green

Publisher: Royal Society of Chemistry

Published: 1999

Total Pages: 510

ISBN-13: 0854043187

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Organometallic chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in catalysis synthetic organic chemistry and also in the development of new materials. This Specialist Periodical Report aims to reflect these current interests reviewing progress in theoretical organometallic chemistry, main group chemistry, the lanthanides and all aspects of transition metal chemistry. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.