Cancer facts for people over 50
Author:
Publisher:
Published: 2005
Total Pages: 12
ISBN-13:
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Breast Cancer Metastasis and Drug Resistance
Author: Aamir Ahmad
Publisher: Springer Nature
Published: 2019-08-27
Total Pages: 432
ISBN-13: 3030203018
DOWNLOAD EBOOKResistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Hormone Replacement: Therapy and Breast Cancer Risk
Author: R.D. Mann
Publisher: CRC Press
Published: 1992-07-15
Total Pages: 321
ISBN-13: 9781850703990
DOWNLOAD EBOOKThis book covers a topic of considerable current interest and presents many of the most significant research findings available to date. Workers at the forefront of research on hormone replacement therapy and the implications for the risk of breast cancer were invited to attend a special Conference at the Royal Society of Medicine in London in September, 1991, where the latest data were presented to a distinguished audience and the implications of this research were discussed. The volume reviews various aspects of HRT and breast cancer, the physiology of the menopause, the current use of HRT in practice, osteoporosis and epidemiology and presents results from a range of European, American and Australian studies on the role of breast cancer and HRT, finishing with an overview of benefits, use and cost-effectiveness and a general summary. The book represents a definitive statement of current knowledge in this field and an informative update on the implications of recent research. It will be a valuable addition of special significance to the libraries of all those concerned with hormone replacement therapy and the study of breast cancer.
Adjuvant Therapy for Breast Cancer
Author: Monica Castiglione
Publisher: Springer Science & Business Media
Published: 2009-07-11
Total Pages: 483
ISBN-13: 0387751157
DOWNLOAD EBOOKAdjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Cancer in the Elderly
Author: Carrie P. Hunter
Publisher: CRC Press
Published: 2000-03-01
Total Pages: 591
ISBN-13: 0824746457
DOWNLOAD EBOOKThis book presents comprehensive assessment and up-to-date discussion of the epidemiology, prevention, and treatment of cancer in the elderly, highlighting the growing demands of the disease, its biology, individual susceptibility, the impact of state-of-the-art and emerging therapies on reducing morbidity, and decision making processes. Describ
Principles and Practice of Geriatric Surgery
Author: Ronnie Ann Rosenthal
Publisher: Springer Science & Business Media
Published: 2011-07-12
Total Pages: 1364
ISBN-13: 1441969993
DOWNLOAD EBOOK"In the preface to this impressive and well-produced book, the editors state that their aim is not to describe a new surgical specialty, since most surgeons will soon need to be "geriatric surgeons," but to assemble a comprehensive account that will allow "all providers of healthcare to the elderly to understand the issues involved in choosing surgery as a treatment option for their patients." This is a useful book that deserves to do well. I hope that the editors and their publisher will have the stamina to make this the first of several editions, as it is clear that updated information about surgery in the elderly will be required to keep pace with this important field." NEJM Book Review
Fulfilling the Potential of Cancer Prevention and Early Detection
Author: National Research Council
Publisher: National Academies Press
Published: 2003-05-07
Total Pages: 564
ISBN-13: 0309170133
DOWNLOAD EBOOKCancer ranks second only to heart disease as a leading cause of death in the United States, making it a tremendous burden in years of life lost, patient suffering, and economic costs. Fulfilling the Potential for Cancer Prevention and Early Detection reviews the proof that we can dramatically reduce cancer rates. The National Cancer Policy Board, part of the Institute of Medicine, outlines a national strategy to realize the promise of cancer prevention and early detection, including specific and wide-ranging recommendations. Offering a wealth of information and directly addressing major controversies, the book includes: A detailed look at how significantly cancer could be reduced through lifestyle changes, evaluating approaches used to alter eating, smoking, and exercise habits. An analysis of the intuitive notion that screening for cancer leads to improved health outcomes, including a discussion of screening methods, potential risks, and current recommendations. An examination of cancer prevention and control opportunities in primary health care delivery settings, including a review of interventions aimed at improving provider performance. Reviews of professional education and training programs, research trends and opportunities, and federal programs that support cancer prevention and early detection. This in-depth volume will be of interest to policy analysts, cancer and public health specialists, health care administrators and providers, researchers, insurers, medical journalists, and patient advocates.
Cancer and Aging
Author: M. Extermann
Publisher: Karger Medical and Scientific Publishers
Published: 2013-01-18
Total Pages: 179
ISBN-13: 3318023078
DOWNLOAD EBOOKCancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.
Breast Cancer Research. Ageing as Predisposing Factor
Author: Gabby Ian
Publisher:
Published: 2021-07-08
Total Pages: 40
ISBN-13: 9783346482822
DOWNLOAD EBOOKDiploma Thesis from the year 2018 in the subject Health - Nursing Science - Geriatric Care, grade: A, Kenyatta University, language: English, abstract: This work investigates whether age is among the predisposing factors for breast cancer. Breast cancer is heterogeneous malignant cells whose specific age profiles exponentially increases until menopause after which it rises gently slowly thereby reflecting the superimposition of the early and late onset rates of breast cancer. The early onset breast cancers represent mainly the untimely life transforming or inherited consequences on the undeveloped epithelium, while late-onset breast cancers in most cases are likely to follow an extended exposure to supporting stimulus of vulnerable epithelium, which has botched to age normally. Biomarker studies and clinical observations indicates that the latter staged breast cancer types often develop slowly and are less biologically aggressive compared to the early staged breast cancers despite being under the control of hormone receptors such as growth factor receptor abbreviated as (HER2) and estrogen receptor (ER), expressions hence supporting the conclusion that breast cancer biology is age dependent. Approximately twelve percent of women across the globe in the current society are annually affected by breast cancer. Moreover, while breast cancer incidence increases with age advancement, patients of younger age at diagnosis are largely associated with increase in the mortality rate. This research discusses most of the age-related factors, which affect the identification or diagnosis, treatment, and management of breast cancer incidence; examining main concepts and exploring vital areas, which calls for additional research. Ageing as a predisposing factor for breast cancer will be examined in connection to diagnosis and treatment with special reference to nodal status, hormone factors, breast cancer subtypes and genetic status. Further, although narrowly, the study will also
Journal of the National Cancer Institute
Author:
Publisher:
Published: 2014
Total Pages: 676
ISBN-13:
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